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Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic bat-borne paramyxoviruses included in the WHO Blueprint priority diseases list. NiV has two membrane-anchored glycoproteins, the attachment protein (G) and fusion (F) protein, that mediate receptor binding and entry into host cells. G binding to the cellular receptor, ephrin-B2 or -B3, triggers a conformational change in F that facilitates fusion of the viral and cellular membranes.
Using high-quality and correct virus antigens for immunization can help you obtain optimal results when it comes to vaccine development, especially when it comes to the correct native structure or protein conformation. Put your trust in ACROBiosystems’ verified viral antigens to accelerate your vaccine development.
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