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Evaluate MMR protein status with the only companion diagnostic to identify endometrial cancer patients eligible for JEMPERLI® (dostarlimab-gxly)

Roche Diagnostics is pleased to announce the U.S. FDA approval of VENTANA MMR RxDx panel as an aid in identifying patients eligible for treatment with the anti-PD1 immunotherapy JEMPERLI for MMR deficient endometrial carcinoma.

Endometrial cancer (EC) is the most common type of cancer affecting the female reproductive organs with nearly 66,000 cases expected in the U.S. in 2021. (incidence data from the American Cancer Society, www.cancer.org)

Endometrial cancer has been associated with genetic alterations, including MSI. Deficient MMR (dMMR) and MSI-High (MSI-H) is reported in 20-40% of cases. For this reason, NCCN guidelines recommend universal testing of endometrial carcinomas for MMR protein status.

Now your lab can help identify endometrial cancer patients eligible for JEMPERLI with the only Class III IHC panel available.

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* Incidence data from the American Cancer Society, www.cancer.org

VENTANA is a trademark of Roche.
JEMPERLI is a trademark owned by or licensed to the GSK group of companies.
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