October Newsletter

Message From the President

October 13th through the 17th the North American 3Rs Collaborative is heading to The Mile High City to meet with other professionals in the laboratory animal science community dedicated to research animal welfare and the 3Rs at the 70th Annual National American Association for Laboratory Animal Sciences Meeting. Our organization has undergone some exciting changes this year and we look forward to sharing how we are bringing transformational solutions to advancing science, innovation and animal welfare to individual collaborators and collaborating organizations. We are currently seeking vendor collaborators for our Complex In Vitro Models work stream and Translational Biomarkers Hub. Whether you are a company that develops emerging technologies, provides data management solutions, or would like to learn more about how emerging technologies can provide 3Rs value to your work or organization, we invite you to stop by our booth (#138) to learn more. We are open to all levels of membership and collaborator engagement. 
   
We also invite you to join us at a session we’re pleased to be cosponsoring with The National Centre for the Replacement, Refinement & Reduction of Animals in Research on Reproducibility in Animal Research , being held Tuesday Oct 15th. See details below.
Finally, we are excited to share that we have extended our NA3RsC Fellowship application deadline until Friday, October 18th!

To learn more about who we are, our work streams and how we are facilitating collaboration for 3Rs impact and reach, please visit us at booth #138 . Join us and start collaborating today!

With gratitude, 

Natalie A Bratcher 
NA3RsC President 
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If you are considering making a donation to our organization, the link below takes you to our membership benefits page. Click on NA3RsC Membership Form. Complete, write a check and mail to address listed. Thank you!
If you are interested in becoming more active with the
 North American 3R's Collaborative :
National AALAS
Visit our booth - #138
Look for NA3RsC Officers and Board Members in the National AALAS Program:
Reproducibility in Animal Research
Tuesday, October 15, 8:00 AM - 10:15 AM/Room: Mile High Ballroom 4A
Leader/Moderator: Natalie A Bratcher
Facilitator: Sara R Oglesby
This Seminar is sponsored in part by UK National Centre for the 3Rs (NC3Rs) and the North American 3Rs Collaborative (NA3RsC).
8:00-8:05am Introduction 
Natalie Bratcher
8:05-8:30am Improving Research Reproducibility: The Revised ARRIVE
Guidelines and the Experimental Design Assistant 
Esther Pearl 
8:30-8:55am Standardization and the Reproducibility Paradox in Animal
Research
Hanno Würbel 
8:55-9:20am Refining Animal Work to Enhance Research Reproducibility 
Kelly Metcalf Pate
9:20-9:45am Considering What Matters in the Vivarium when Addressing
the Reproducibility Problem
Jennie LS Lofgren
9:45-10:15am Questions & Answers
All Presenters
Who's Driving the 3Rs/Welfare Science and Does It Matter?
Wednesday, October 16, 8:00 AM - 10:15 AM/Room: Mile High Ballroom 4A
Leader/Moderator: Natalie A Bratcher
Facilitator: Sara R Oglesby
One Health Approach for the Animal Caregiver: Occupational Health, Human-Animal Bond, and Compassion Fatigue
Wednesday, October 16, 2:45 PM - 5:00 PM/Room: Mile High Ballroom 1A Leaders: Sally Thompson-Iritani , J Preston Van Hooser
Moderator: Sally Thompson-Iritani

Change Is Coming: Updates to the AVMA Panel on Euthanasia
Wednesday, October 16, 12:30 PM - 2:00 PM/Room: 501
Leader: Debra L Hickman
Moderator: Natalie A Bratcher
Facilitator: Beth A Skiles
Panelists: Samuel C Carter, Emily G Patterson-Kane, Natalie A Bratcher , Kathleen R Pritchett-Corning
The AVMA is in the process of updating the AVMA Guidelines on Euthanasia, with special emphasis on updates to the requirements for CO2 for laboratory animals. Euthanasia remains one of the most important aspects of laboratory animal welfare. In this session, we will review the changes and discuss ways for institutions to implement the changes. In addition, data supporting these changes and how to best implement them for optimal welfare will also be discussed. The target audience is anyone interested in learning about and discussing euthanasia and animal welfare refinement; those using euthanasia methods in rodents; scientists, technicians, and veterinarians; and IACUC members and facility managers.
Technical Trade Presentation
Track 1 - Capitalizing Data Technology
Improved Study Workflows and Animal Welfare through the Use of Digital Biomarkers
Sunday, Oct 13, 2:20 pm - 2:40 pm/Room 205
Speaker: Laura Schaevitz , Vium
Moderator: Pat Guider, a-tune Software Inc.
This session will examine a number of topics including how digital data can be used to create specifications around normal animals prior to study start, improve randomization, design adaptive studies to reduce animal numbers, and creation of algorithms to alert of unhealthy animals to reduce losses.

21st Century Cures Act: Where Are We Now?
12:30 PM - 2:00 PM/Room: 401
Leader/Moderator: Aubrey Schoenleben
Facilitator: Chrissie Staunton
Panelist: William G Greer, Sally Thompson-Iritani , Patricia A
Brown, Robert Gibbens
The 21st Century Cures Act, Section 2034(d) directed federal agencies to “complete a review of applicable regulations and policies for the care and use of laboratory animals and to make revisions, as appropriate, to reduce administrative burden on investigators while maintaining the integrity and credibility of research findings and the protection of research animals.” In response, a working group was convened that included representatives from NIH, USDA, and the FDA. The working group employed several strategies to identify regulations and policies that contribute to administrative burden, such as reviewing published reports and surveys on the topic, hosting listening sessions, and collecting feedback from the public through a request for information. We will provide an update on the status of the 21st Century Cures Working Group report, including discussion on upcoming changes to regulations and policy, how federal agencies are improving coordination and harmonization, and new training and resources being developed. Panel members will also discuss how institutions can implement some of the proposed suggestions for reducing burden, such as the use of best practices offered through the IACUC Administrators’ Association and standard procedures included in the Federal Demonstration Partnership’s CUSP project.

Platform Session: Laboratory Investigations 4
PS105 - Reducing Variability in Mouse Studies Through Continuous Data Collection
Wednesday, Oct 16, 2:15 pm - 5:00 pm
Platform Members: Naomi Nayoung Lee, Alexa Renee Personett, Harvey Ramirez, Morika Danielle Williams, Patricia G. Hedenqvist, Charlotte Hotchkiss, Amy Muehlmatt, Laura Schaevitz , Kathryn E. Nichols, Andrew Schile

Platform Session: Animal Welfare, Training, and the 3Rs: Primate Behavior
PS74 - The interplay between Temperament and Operant learning in Primates to Cope with Medical Management
Wednesday, Oct 16, 8:00 am - 11:00 am
Platform Members: Kristine Coleman, Mollie Bloomsmith, Angelika N Rehrig, Kelly Morrisroe, Lisa Houser, Jaine E Perlman, Steven J Schapiro, Elizabeth Magden, Melanie Graham , Dawn M Abney, Jorg Luft

W-07 Workshop (2 sessions)
Teaching Monkeys to Cooperate with Restraint: Using Positive Reinforcement Training and Temperament Testing Methods
Monday, Oct 14, 1:00 PM - 5:00 PM/Tuesday, Oct 15, 8:00 am - 12:00 pm
Monday Leaders: Jaine E. Perlman, Jennifer L. McMillian , Mollie Bloomsmith, Kristine Coleman, Mark J. Prescott
Tuesday Leaders: Jennifer L. McMillan , Mollie Bloomsmith, Kristine Coleman, Mark J. Prescott, Andrea Franklin
Positive Reinforcement Training (PRT) is an important refinement in the care of nonhuman primates and an effective means of improving their welfare. The goals of this workshop are to introduce participants to animal training terminology and technique, to teach PRT techniques as they apply to restrain procedures and to teach methods to assess and quantify temperament in monkeys and to use this information to develop individualized training plans.
These workshops sponsored in part by Lomir, Hybex, Britz & Company, Carter2Systems, NC3Rs and NA3RsC.

W-11 Workshop
Improving Your Suturing and Rodent Surgery Aseptic Technique?
Tuesday October 15, 1:00 pm - 5:00 pm
Leaders: Marcel I. Perret-Gentil, Laurie Long, Szczepan W. Baran , Katherine Nolan, Natalie Celeste, Sarah Genzer
Participants will learn and refine commonly used suture, knot-typing, and rodent surgical draping techniques. The workshop will focus on appropriate hand-eye coordination as well as aseptic procedures. A state-of-the-art inanimate model will be introduced. This session is appropriate for individuals with minimal suturing skills as well as those wishing to upgrade their skills.
Monthly 3 minute - 3Rs podcast
Co-produced with LabAnimal & NC3Rs
July Podcast
August Podcast
September Podcast
Thank you!
We would like to thank the following institutions for grants/financial assistance in 2019 which supported our website and educational opportunities.



GSK
2020 Elections
It is hard to believe that 2020 is just around the corner. That means we need to schedule elections:

  • Vice-President Elect

  • Board of Directors (2 positions)

If you are interested in being an active member within our organization, please consider running for a position (3 year term). Or if you know of someone that you think would be perfect, let us know at contactus@na3rsc.org .
2019 Officers
President: Natalie Bratcher, AbbVie
Vice President: Lisa Stanislawczyk, Bristol-Myers Squibb
Vice President Elect: Benjamin Cappiello, AxoSim, Inc.
Past President: Mary Ann Brannon-Vasbinder, GSK
Secretary: Norman Peterson, AstraZeneca
Treasurer: Jennifer McMillan, Emory University/Yerkes
2019 Directors
Szczepan Baran, Novartis
Alan Hoberman, Charles River
Melanie Graham, University of Minnesota
Jerry Poling, Eli Lilly
Sally Thompson-Iritani, Washington National Primate Research Center
Laura Schaevitz, Vium, Inc.
Sharon Ostergaard, Bristol-Myers Squibb
Judy MacArthur-Clarke, JMC Consultancy and JMC Welfare International
Suzanne Fitzpatrick, Food and Drug Administration
The North American 3R's Collaborative​
www.na3rsc.org
Alice White McVey, Operations Consultant
919-608-9550
October Newsletter
Contact us to add YOUR 3Rs content to our next newsletter contactus@na3rsc.org