Updated Guideline: PEP to Prevent HIV Infection

Updated by lead author Dr. Ethan Cowan, with the Medical Care Criteria Committee (MCCC), the October 2024 Post-Exposure Prophylaxis (PEP) to Prevent HIV Infection guideline provides New York State clinicians with effective care management strategies for individuals who report a potential exposure to HIV.

Updates to the guideline include:

• New recommendations, discussion, and references added on bictegravir/tenofovir alafenamide/emtricitabine (BIC/TAF/FTC) as a preferred single-tablet PEP regimen for nonpregnant and pregnant adults
• Discussion added on PEP-in-pocket, which involves giving individuals with an anticipated low frequency of high-risk HIV exposures a prescription for PEP

Go to the guideline

Contents:

• Purpose of This Guideline
• Risk of Infection Following an Exposure to HIV
• Rationale for PEP and Evidence of PEP Effectiveness
• First Dose of PEP and Management of the Exposure Site
• Evaluating Exposure Risk
• Source HIV Status and Management
• Baseline Testing of the Exposed Individual
• Selecting and Initiating a 28-Day Course of PEP
• Counseling and Patient Education

• Providing PEP Medications and Other Services
• Follow-Up of the Exposed Individual
• Sequential HIV Testing and Laboratory Monitoring
• Management of Potential Exposure to Hepatitis B Virus
• Management of Potential Exposure to Hepatitis C Virus
• All Recommendations
• All Good Practices
• Supplementary Materials
• All Tables, Figures, and Boxes
• Printable PDF

Updated Guideline: Prevention and Management of Hepatitis A Virus Infection in Adults With HIV

Contents:

• Purpose of This Guideline
• HAV Prevention
• Management of HAV/HIV Coinfection
• All Recommendations
• Printable PDF
• Slide Set

Lead author Dr. Hector I. Ojeda-Martinez, with the MCCC, has revised the September 2024 Prevention and Management of Hepatitis A Virus Infection in Adults With HIV guideline for New York State clinicians in ambulatory settings who provide primary and HIV specialty care for adults who have or are at risk of acquiring hepatitis A virus infection. Resources and references have been updated throughout the guideline.

Go to the guideline

PrEP Aware Week Webinars From CEI

• 10/21: Clinical Strategies for HIV Prevention: PEP & PrEP
• 10/22: PrEP for Adolescents and Young Adults
• 10/23: PrEP for Older Adults
• 10/24: HIV Treatment and Prevention for All Women
• 10/25: Long-Acting Injectables Implementation – Lessons Learned (Focus on PrEP)

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• 2024 CEI Annual Survey - Please complete the 2024 CEI Annual Survey
• NYS Medicaid Update Special Edition – Updates to New York State Medicaid Coverage of Coronavirus Disease 2019 Services
• HIVinfo: Updates to the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV

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Updated Guideline: Second-Line ART After Treatment Failure or for Regimen Simplification

• Purpose of This Guideline
• Identifying and Managing Virologic Failure
• ART Changes to Address Drug Resistance
• ART Changes for Adverse Effects, Drug-Drug Interactions, or Pregnancy
• ART Changes for Regimen Simplification
• Resumption of ART After a Treatment Interruption
• All Recommendations
• Printable PDF
• Pocket Guide
• Slide Set

Updated Resource: ART Drug-Drug Interactions

• Purpose of This Resource
• Identifying Drug-Drug Interactions
• Classifications and Mechanisms of Drug-Drug Interactions
• Drug-Drug Interactions by Antiretroviral Medication Class
• Drug-Drug Interactions by Common Medication Class
• Printable PDF

CEI:

• 10/16: Preconception and Perinatal Care for Persons Living with HIV
• 10/30: Buprenorphine in Practice: A Case-based Discussion

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General:

• 10/10: NE AETC: 2024 Northeast Alliance for LGBTQ+ Health Conference
• 10/16: IDWeek 2024
• 10/17: ASAM: 2024 State of the Art Course in Addiction Medicine
• 10/21: NYSDOH AI: PrEP Aware Week: PrEP for All Ages
• 10/21: FDA and NIH Joint Public Meeting on Advancing Smoking Cessation Priorities
• 10/23: MW AETC: UTAH Aids Education & Training Center LGBTQIA+ ECHO Series
• 10/30: ASAM eLearning: Integrating Addiction Medicine with Treatment Courts
• 11/13: ASAM eLearning: Integrating Addiction Medicine with Treatment Courts
• 11/13: Native Transformations in the Pacific Northwest: Stories of Strength in a Public Health Crisis
• 11/17: 2024 Ryan White HIV/AIDS Program Clinical Conference
• 11/20: MW AETC: UTAH Aids Education & Training Center LGBTQIA+ ECHO Series
• 12/10: NYSDOH AI: 9th Annual Ending the Epidemic Summit and 26th Annual World AIDS Day: Unraveling Syndemics: A Community Response, Shared Solutions
• 12/10: VASAM: WHAM #4: Modernizing Methadone Treatment in 2024
• 02/04: National Advisory Council on Drug Abuse: Open Session
• 03/09: CROI 2025
• 03/17: NIDA Genetics and Epigenetics Cross-Cutting Research Team Meeting
• 04/24: ASAM 56th Annual Conference – Innovations in Addiction Medicine and Science
• 05/13: National Advisory Council on Drug Abuse: Open Session
• 05/14: CRAN Joint Council Meeting

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