NSF has released an updated version of the NSF Grants.gov Application Guide (NSF 24-006). In general, the Guide has been revised to match the changes in NSF's Proposal and Award Policies and Procedures Guide (PAPPG) (NSF 24-1). A summary of changes by chapter is provided at the beginning of the document. 

The guide will be effective for applications submitted (via Grants.gov) or due on or after May 20, 2024. The guidelines in grantsgovguide0123 are applicable to proposals submitted before May 20, 2024.

Effective June 12, 2024, NIAID will enhance the maximum salary and research support given on NIAID K99 awards through the Parent and MOSAIC notices of funding opportunities (NOFOs) or any reissues of these NOFOs, on NIAID K25 awards through the Parent NOFO or any reissue, and on NIAID K01 awards through the Parent NOFO or any reissue.

NIAID will no longer accept renewal (Type 2) applications through NOFOs for application due dates on or after June 12, 2024 or any reissues: Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) and Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required).

Furthermore, applications from full professors will not be accepted by NIAID. Applicants must be mid-career faculty at the Associate Professor level or equivalent when applying.

Starting with applications received on or after September 25, 2024, NIAID will limit the total number of predoctoral and/or postdoctoral training slots to a maximum of 8 trainee slots/training grant in any given year for the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) or any reissuance of this funding opportunity as an operational accommodation due to budgetary constraints. This is for both competitive and non-competitive T32 grants.

Current NIAID T32 grantees with 10 or more than 10 trainee slots/year will need to reduce their number of slots by not replacing vacant slots until the 8-slot limit is reached and maintained. For competitive renewal (T2) applications, the maximum increase in trainee slots from the previous non-competiting (T5) year will be 2, with a maximum 8-slot limit.

As a part of our ongoing effort to provide family-friendly work environments to the NIH-supported workforce, starting with FY2024 awards, the childcare support for applicable NRSA individual fellowships and institutional training awards will be raised to $3000. FY2024 training and fellowship awards that were given before the date of this notice will be revised to retroactively reflect the increase in support for all eligible slots (training) and individuals (fellowships).

The extramural research community is being informed about planned changes to the Research Performance Progress Report (RPPR) instructions to address the NIH Data Management and Sharing Policy. Once OIRA approves, the NIH RPPR Instruction Guide will be posted on the Research Performance Progress Report (RPPR) page. NIH is going to implement the new questions for RPPRs submitted on or after October 1, 2024.NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Reporting Data Management and Sharing (DMS) Plan Activities in the Research Performance Progress Report (RPPR) NOT-OD-24-123. NIH

This notice provides the research and research training community with an overview of application and peer review changes impacting grant applications submitted for due dates on or after January 25, 2025, including:

•    Simplified Review Framework for Most Research Project Grant Applications
•    Revisions to the NIH Fellowship Application and Review Process
•    Updates to Reference Letter Guidance
•    Updates to NRSA Training Grant Applications
•    Updated Application Forms (FORMS-I)
•    Common Forms for Biographical Sketch and Current and Pending (Other) Support

NIH will provide more information and guidance on these initiatives throughout 2024, which will be referred to in this notice as well.

The purpose of this notice is to provide updates and plans for implementing the simplified peer review framework for most research project grant applications announced in October (NOT-OD-24-010). It updates and clarifies the activity codes impacted, the plans to update funding opportunities, and the timing of when application forms will be available.

NIH is on schedule to implement the simplified review framework for applications that have due dates on or after January 25, 2025.

The applicant and recipient communities are notified of changes to grant application forms and application guide instructions for due dates on or after January 25, 2025 through this notice.

The application forms below have substantial modifications (i.e., new/deleted/modified fields). All other forms are limited to an OMB expiration date change.

•    PHS 398 Research Training Program Plan
•    PHS Fellowship Supplemental Form
•    PHS Assignment Request Form
•    PHS 398 Cover Page Supplement Form

This notice informs about the modifications made to the application and peer review process for NIH and AHRQ fellowship applications beginning with submissions that are due after January 25, 2025. The overall goal of the changes is to facilitate the mission of fellowship peer review - to identify the most promising candidates and provide individualized training opportunities that will assist them along their path to support the advancement of the biomedical research enterprise.

The Office of Extramural Research (OER) has developed a quick decision tool that should assist you with determining if your research involves human subjects, may be considered exempt from Federal regulations, or is not considered human subjects research. This tool should not be used as the sole determination of exemption.

My bibliography contains information on eRA Commons users who have received grants in their portfolio. They are able to determine whether their publications comply with the NIH Public Access Policy, initiate the compliance process and link their publications to NIH extramural awards. The steps to manage compliance with the NIH public access policy can be found here.

A. Peer-reviewed cancer research program:

1.Advancing Cancer Care through Clinical Trials Award

o  Pre-application submission deadline: July 24, 2024 5:00 p.m. Eastern Time

o  Invitation to Submit an application: August 29, 2024

o  Full application submission deadline is October 15, 2024 11:59 p.m. Eastern Time

2.Virtual Cancer Center Director Award

o  Pre-application submission deadline: July 24, 2024 5:00 p.m. Eastern Time

o  Invitation to Submit an application: August 29, 2024

o  Full application submission deadline is October 15, 2024 11:59 p.m. Eastern Time

3.Convergent Science Cancer Consortium Award

o  Pre-application submission deadline: July 24, 2024 5:00 p.m. Eastern Time

o  Invitation to Submit an application: August 29, 2024

o  Full application submission deadline is October 15, 2024 11:59 p.m. Eastern Time 

4.Career Development Award – Scholar Option

o  Pre-application submission deadline is July 12, 2024 5:00 p.m. Eastern Time

o  Full application submission deadline is July 26, 2024 11:59 p.m. Eastern Time

5.Patient Well-Being and Survivorship Award

o  Pre-application submission deadline is July 12, 2024 5:00 p.m. Eastern Time

o  Full application submission deadline is July 26, 2024 11:59 p.m. Eastern Time

B. Funding announcements released:

1.The Traumatic Brain Injury and Psychological Health Research Program has released the following funding opportunities:

·       Clinical Trial Award

·       Emerging Topics Research Award *New for FY24

·       Focused Program Award

·       Health Services Research Award

·       Translational Research Award

To view the funding opportunity announcement and submit a pre-application, click here. 

2.The Vision Research Program has released the following funding opportunities:

·       Clinical Trial Award

·       Focused Translational Team Science Award

·       Investigator-Initiated Research Award

·       Translational Research Award

To view the funding opportunity announcement and submit a pre-application, click here.

3.The Lupus Research Program (LRP) released program announcements for the following funding opportunities:

·       Idea Award

·       Impact Award

·       Transformative Vision Award

·       Transformative Vision Development Award

To view the funding opportunity announcement and submit a pre-application, click here.

4.The Parkinson’s Research Program (PRP) released program announcements for the following funding opportunities:

·       Early Investigator Research Award

·       Investigator-Initiated Research Award

To view the funding opportunity announcement and submit a pre-application, click here.

5.The Breast Cancer Research Program (BCRP) released program announcements for the following funding opportunities:

·       Breakthrough Award Levels 1 and 2

·       Clinical Research Extension Award

·       Era of Hope Scholar Award

·       Transformative Breast Cancer Consortium Development Award

To view the funding opportunity announcement and submit a pre-application, click here.

6.The Bone Marrow Failure Research Program released the following funding opportunities:

·       Idea Development Award

·       Investigator-Initiated Research Award

To view the funding opportunity announcement and submit a pre-application, click here.

7.The Neurofibromatosis Research Program released the following funding opportunities:

·       Neurofibromatosis Research Academy Leadership Award

To view the funding opportunity announcement and submit a pre-application, click here.

8.The Alcohol and Substance Use Disorders Research Program  released the following funding opportunities:

·       Consortium Award

To view the funding opportunity announcement and submit a pre-application, click here.

Due: July 8,2024 @ 4pm

Amount: $400,000/2 years

The Damon Runyon-Rachleff Innovation Award is designed to provide support for the next generation of exceptionally creative thinkers with “high-risk/high-reward” ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis, or treatment of cancer. The Innovation Award is specifically designed to provide funding to extraordinary early career researchers who have an innovative new idea but lack sufficient preliminary data to obtain traditional funding. It is not designed to fund incremental advances. Applications will be accepted from all scientific disciplines provided that the proposed research meets the selection criteria.

Eligibility: The applicant must have received an MD, DO, PhD, or MD/PhD degree. Tenure-track Assistant Professors within the first five (5) years of obtaining their initial Assistant Professor position (Cut-off date: July 1, 2019). Clinical Instructors and Senior Clinical Fellows (in the final year of sub-specialty training) holding an MD, MD/PhD, DO who are pursuing a period of independent research before taking a tenure-track faculty position. Such individuals must have an exceptional record of research accomplishment, dedicated laboratory space and the support of their institution. Applicants with a background in multiple disciplines are especially encouraged to apply.



If you have any questions, please contact amcinerney@montefiore.org.

This two-year grant of $130,000 is a joint effort to encourage and support a postdoctoral or clinical research fellow.

To conduct endometrial cancer research and to establish a successful career path in this field. Projects may be basic, translational, clinical, or epidemiological in nature. There are no citizenship or geographic requirements.

The deadline to submit applications is July 18th, 2024. 

Applicants must have a doctoral degree (including PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree.

At the start of the grant term on November 1, 2024, applicants must:

i) Hold a mentored research position with the title of postdoctoral fellow, clinical research fellow, or the equivalent. Visit the website for eligibility details. 

ii) Have completed their most recent doctoral degree within the past five years (i.e., degree cannot have been conferred before November 1, 2019; the formal date of receipt of doctoral degree is the date the degree was conferred, as indicated on their diploma and/or transcript).

Click here for more details.

This three-year grant of $450,000 is for early-career investigators to promote and support creative, paradigm-shifting cancer research that may not be funded through conventional channels. Proposed research may be basic, translational, or clinical in nature and must represent a highly innovative approach to a major contemporary challenge in Fanconi Anemia-related cancer research. The LOI deadline is July 9th, 2024 at 1 PM (EST).

Request for Letters of Intent (due July 13, 2024)

A Breath of Hope Lung Foundation (ABOHLF), in collaboration with its panel of experts in the field of oncology, will evaluate the eligibility and research aim submitted in response to our recent request for letters of intent.

Review RFP here or submit your letter of intent here.

Read about our amazing friend, Peg Fisher-Jullie, for whom this grant is named.

RFP ELIGIBILITY for this early career award includes the following criteria:

• In first ten years of faculty position, a mentor is required
• Must hold a doctoral degree (MD, PhD, DO, DrPH, or equivalent)
• Must be employed by a U.S. research institution (proof of Visa required)
• If project involves people or animals, you must have received approval from your institution’s review board before the funds are disbursed

Preferred topics: Specifically, proposals that address major questions addressing common mutated lung cancers is required. The EGFR biomarker is a high priority in this award. Topic areas include, but are not limited to the following ideas:

• Strategies to overcome resistance to immunotherapy in EGFR mutated lung cancer.
• Predictive and prognostic markers to identify responders and non-responders
• Approaches to overcome acquired resistance to targeted therapies
• Novel approaches to treating mutation-driven NSCLC
• Understanding mechanisms of resistance to immunotherapy in EGFR mutated lung cancer 
• Improving prognostic value and predictive value for genetic heterogeneity across multiple mutation-positive NSCLC patients
• Identifying disease-causing variants in oncogenes for NSCLC patients that may benefit with targeted therapies

Timeline for Submission and Review

• July 5, 2024: Announcement – Request for letter of inquiry (LOI)
• July 13, 2024: Deadline for LOI submission – online forms reviewed by local ABOH research committee
• July 22, 2024: Up to 15 investigators invited to submit full proposal
• September 13, 2024: Deadline for full proposal submission
• September 13 – October 11: National Scientific Advisory Committee scores proposals
• October 14 – 28, 2024: ABOH Research Committee reviews scores, conducts phone interviews with finalists and their mentor, identifies winner
• October 28, 2024: Winner notified
• November 1, 2024: Winner announced upon receipt of signed grant contract from institution
• November 1, 2024: First payment of $37,500 mailed to institution as soon as ABOH receives the signed and returned ABOH grant contract 

Questions? Reach out to research committee leads at research@abreathofhope.org or Nancy@abreathofhope.org.

A Breath of Hope Lung Foundation is a 15-year-old national nonprofit based in Minneapolis, Minnesota. Learn more about this organization at https://abreathofhope.org/.

• Due: July 15, 2024 (LOI)

• Amount: $375,000/3 years

The program provides flexible support for research projects in basic biology of aging, as well as geroscience (projects that translate advances in basic research on aging biology from the laboratory to the clinic.) The projects should focus on understanding the basic mechanisms of aging rather than disease-specific research. Projects investigating age-related diseases or functional disorders are supported only if approached from the point of view of how basic aging processes may lead to disease outcomes. Projects that deal strictly with clinical problems such as the diagnosis or treatment of disease, health outcomes, or the social context of aging are not eligible.

Eligibility: Junior investigators (MDs and/or PhDs) with at least 3 years of independent research. Must be no more than 12 years beyond the start of postdoctoral research training as of July 15, 2024. Must have published at least 3 last author research papers in an international peer reviewed journal from independent work carried out in your own lab. Investigators who may not have previously worked in the area of aging, but whose research interests and expertise are relevant and could lead to discoveries or new understanding in the biology of aging or geroscience are strongly encouraged to apply.

• Link: New Investigator Award

LOI Deadline: July 18, 2024 @ 3 pm

Amount: $505,000/5 years

The Investigators in the Pathogenesis of Infectious Disease (PATH) program provides opportunities for assistant professors to bring multidisciplinary approaches to studying human infectious diseases. The program aims to provide accomplished investigators at the assistant professor level with opportunities to study what happens at the points where the systems of humans and potentially infectious agents connect. The program supports research that sheds light on the fundamentals that affect the outcomes of these encounters: how colonization, infection, commensalism, and other relationships play out at levels ranging from molecular interactions to systemic ones. The program intends to give recipients the freedom and flexibility to pursue new avenues of inquiry, stimulating higher-risk research projects that hold potential for significantly advancing our understanding of how infectious diseases work and how health is maintained. BWF encourages submissions from those working in protozoan and metazoan parasites, protists, and fungi. Viral, bacterial, immune, and multi-species work is likewise encouraged. Work related to malaria, tuberculosis, and AIDS is appropriate for this program. BWF encourages submissions focusing on climate change and its impact on the pathogenesis of infectious disease and human health. BWF particularly encourages human health-relevant applications from veterinary scientists.

Eligibility: Candidates who will be promoted to Associate Professor by November 14, 2024, are not eligible to apply. The ideal candidate is an accomplished investigator at the mid-to-late assistant professor level with an established record of independent research in a tenure-track position or its well-supported equivalent in non-tenure offering departments. Candidates must have an established record of independent research. Citizens and non-citizen permanent and temporary residents of the U.S. and Canada who are legally qualified to work in the U.S. or Canada are eligible.

Link: Pathogenesis RFP

Contact: Audrey McInerney (amcinerney@montefiore.org) for assistance.

• Due: August 1, 2024 (LOI)

• Amount: $500,000 over 3 years

Project should be innovative, high-risk, potentially high-yield projects that focus on

specific areas of suicide prevention. Project may be focused on the following goals: addressing short-term suicide risk, reducing the national suicide rate by 20%; or “blue-sky research grants” for impactful research that will achieve significant goals (open to all fields of study).

Link: Research Focus grants | AFSP

Contact: Audrey McInerney (amcinerney@montefiore.org) for assistance.

• Due: August 2, 2024

• Amount: $200,000-$1.5 million/2-5 years

Gateway funds Phase I and II patient-centered cancer clinical trials that have the

potential to shift the paradigm for standard of care. The foundation strives to fund treatment-based studies at the bedside, including all types of cancers. The Traditional Grant Program funds core grants for early phase clinical trials for cancers of all types at renowned institutions around the world.

The focus is on New Investigational Therapies; New Indications; De-escalation of Treatment; Mitigation of Treatment Toxicity; Predictive Biomarkers (with a therapeutic component); and Integrative Medicine in these research areas: Biomarkers (prognostic or predictive with supportive treatment); Gene Therapy; Basket Trials; Immunotherapy; and Targeted Therapies.

Eligibility: An investigator who is ready to conduct a novel, clinical trial in cancer research — one which will have an immediate impact on cancer patients — may apply for funding. The principal investigator will be required to submit a bio-sketch illustrating their work as a clinician and/or researcher.

Link: Gateway for Cancer Research and Gateway All Grant Programs

Contact: Audrey McInerney (amcinerney@montefiore.org) for assistance.

This two-year fellowship of $130,000 is a joint effort to support postdoctoral or clinical research fellows to conduct breast cancer research and to establish a successful career path in this field. Proposed research projects are restricted to basic, clinical, translational or epidemiological projects that substantially advance the field of endocrine therapy in breast cancer. The LOI deadline is August 15th, 2024 at 1 PM (EST).

The College of Medicine would like to submit one candidate’s application for consideration for the 2025 Searle Scholars Program from the Kinship Foundation. The Searle Scholars Program Scientific Advisory Board is primarily interested in the potential of applicants to make innovative and high-impact contributions to research over an extended period of time.  

Grants are set at $300,000 for a three-year period with $100,000 payable in the first year and equal sums payable in the second and third years and are subject to the receipt of acceptable progress reports. Generally, fifteen new awards are granted annually. Awards will be activated on July 1, 2025.  

Eligibility of the applicant: 

• Applicants should have begun their appointment as an independent investigator at the Assistant Professor level on or after May 1, 2023. The appointment must be their first tenure-track position. 
• Applicants are expected to be pursuing independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, and related areas in chemistry, medicine, and the biological sciences.  
• The Searle Scholars Program does not ordinarily support purely clinical research but has supported research programs that include both clinical and basic components. Potential applicants who are unsure if their research is appropriate for the Program are encouraged to examine the research interests of present and former Searle Scholars on this website. The 2023 Searle Scholars are listed here. 

In order to implement the application process for this competition, eligible faculty members are invited to submit preliminary applications, upon the recommendation of the appropriate department chair(s), for review by the Awards Committee. From among these applications, the Committee will make recommendations and will select one candidate, who will be invited to submit the full proposal to the Kinship Foundation by 5:00 pm, September 30, 2024. 

The deadline for submission of preliminary applications for internal review by the Awards Committee is Friday 5 pm, August 16^th, 2024. 

For internal review of your application by the Awards Committee, please send a single (ONE) PDF file containing the following as an email attachment to indranil.basu@einsteinmed.edu: 

1. Candidate Profile Form; download from this link. 
2. A statement outlining the applicant’s career potential and the Department’s plans for his/her future to be obtained from the Department Chairperson, limited to no more than TWO single-spaced pages. 
3. A written proposal containing a title and a description of the proposed research project to be carried out during the grant period, limited to no more than three single-spaced pages, plus one additional page (single spaced) for references with titles included. The font must be 11 point or larger, and the margins should be at least 0.5 inches. Figure legends can use smaller fonts. 
4. A complete curriculum vitae and bibliography. Include invited presentations but not abstracts. Please click here to find the recommended format for curriculum vitae. 
5. Information about present and pending grant support with amounts requested or approved, annual amounts, and duration of award. 

To know in advance about the award and reporting requirements by the Kinship Foundation, please visit the Searle Scholars Program Award Information Page. The Searle Scholars Program accepts nominated applications only through their online application system. Once our Awards Committee selects the nominee, we will assist the nominated candidate to submit the final application to the Kinship Foundation. 

If you have any questions concerning this award or the application procedure, please contact indranil.basu@einsteinmed.edu. 

The Development Office would like to share guidelines for the Fall 2024 Mathers Foundation grant cycle. Our institution may nominate up to 3 applicants in basic science. 

Please submit your project proposals by 5:00 p.m. on Friday, August 23, 2024.

Please note the Development team will handle all LOI submissions. If you have additional questions, please do not hesitate to reach out to institutionalgiving@montefiore.org.

The G. Harold and Leila Y. Mathers Foundation Research Grants – Limited Submission

• Due: October 4, 2024 (LOI)
• Amount: $600,000-$700,000 over 3 years, including 10% indirect rate
• “The mission of The G. Harold and Leila Y. Mathers Foundation is to advance knowledge in the life sciences by sponsoring scientific research that will benefit mankind. Basic scientific research, with potential translational application, is central to this goal, and fundamental to our operating principles.” While the foundation is interested in translational applications, the focus of the proposal should be in basic science. The research should demonstrate potential for significant breakthroughs in the field. Proposals should be high risk/high reward and show a new direction from the PI’s prior efforts. Areas of interest include: Immunology, microbiome, genomics, structural biology, cellular physiology, neuroscience.

• The foundation will not fund COVID-19 research, medical imaging, electrical engineering technology, or plant biology. The foundation also will not fund clinical trials, drug discovery or pre-clinical drug development. Previously declined LOIs/proposals may not be resubmitted. Renewal requests are discouraged. Renewal requests must focus on new directions, “not merely an extension of previously funded research.” Applications with pending federal approval are not given priority.

• Eligibility: To be competitive, the PI must have an independent laboratory, and have a history of “impactful discoveries” and published research studies to share in the LOI phase. While not required, it is recommended that the PI be tenured or in a tenure-track position.

• Selection Process: The Einstein Awards Committee will select up to 3 applicants. PIs should not register in the grant portal until the committee’s decisions are communicated (in mid-September). All LOI submissions must go through the Development Office. If the foundation receives more than 3 submissions from our institution, all Einstein proposals will be disqualified.

• PIs should provide a one page project summary using the template attached, and their CV/biosketch, to institutionalgiving@montefiore.org by 5:00 p.m. on August 23. If you have any questions about the foundation or the application process, please contact institutionalgiving@montefiore.org. 

• Link: Grant Program Overview | Mathers Foundation

Empire State Development’s Division of Science, Technology, and Innovation (“NYSTAR”), Innovation Matching Grants Program (the “IMG Program”) aims to grow small businesses and support the development of new technologies in New York State by providing matching funds for federal Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants.

The New York State Innovation Matching Grants Program will match: 

The award for Phase I applicants, not to exceed $100,000. 

The award for Phase II applicants, not to exceed $200,000. 

and provide technical assistance resources for Phase II and Phase III awards. 

In no event, shall the funding provided from the IMG Program exceed 50% of the federal award. A funding commitment made through the IMG Program demonstrates New York State support to strengthen certain proposals, increase the likelihood that New York State businesses will be awarded competitive federal SBIR/STTR funding, and supports the growth of promising small businesses in New York. Click here for more details.

LLS has released a Request for Proposals (RFP) for its Equity in Access Research Program, which is aimed at funding research in health services. LLS is reissuing their RFP that aims to increase the number of patients who participate in therapeutic cancer clinical trials by promoting access for underrepresented groups. Awards will be a maximum of $2.5 million each over 5 years.

In particular, LLS is in search of proposals that will implement and evaluate interventions that are designed to:

• Mitigate multilevel barriers to therapeutic clinical trial accrual for underrepresented groups
• Quantitatively measure the impact of these interventions on patient accrual

Proposals that address systemic, institutional, and clinician-related barriers that impede clinical trial participation are of particular interest to us. It is not necessary for applicants to have previously conducted research in blood cancer. 

Letters of Intent must be submitted by September 12, 2024 at 3pm ET.

Visit LLS.org/EquityinAccess for the RFP and additional information. If you have any inquiries, please contact researchprograms@lls.org.

The Robert L. Fine Cancer Research Foundation has announced an upcoming funding opportunity in basic and translational pancreatic cancer research. The grant is for $250,000 in direct costs over a two year period. The award is targeted at new and recently established physicians and/or scientists who are dedicated to innovative translational research that would be deemed too risky for funding from conventional government sources. The deadline for the application is August 31^st, 2024 and further details for grant submission can be found at www.rlfcrf.org. 

If there are any questions, please contact the foundation at grants@rlfcrf.org.