-35 publications with 11,000 patients were analyzed.
-Figure: Mean reductions in 24hr systolic pressures varied by agent with statistically significant differences between medications. A similar pattern for diastolic pressures was noted.
-Table: Persistence of anti-hypertensive effect during the 4 hrs preceding the following dose generally mirrored agent half life. (Half life and duration of action are not synonymous but do correlate to some extent. However, olmesartan does maintain its effect for nearly 24 hrs).