Guiding Innovation.

Fostering Partnerships.

July 2024

Newsletter Contents: 17th Annual Catalyst Grant Winners, UWM Professor Rani El Hajjar seeking partnerships, and UWMRF spinout TCare in the news.

UWM Scientists Receive $250,000 for Groundbreaking Research


THE CATALYST GRANT PROGRAM has provided $6 million in support for projects and produced measurable outcomes and transformational impact. This year we have selected 5 new projects, leading to a total of 114 funded projects which have yielded 66 issued patents, 50 patents pending, 30 license/option agreements, and more than $40.7 million in follow-on investments in these UWM technologies to date. This support has also helped in the launch of 18 UWM startup companies.

Thanks to Catalyst Grant Program Donors!


This year's Catalyst Grant Program is made possible through generous donations.


The Lynde and Harry Bradley Foundation has provided continued support for the program since 2007.


New this year, Invenergy supported an award specifically for clean energy research.


Past Catalyst donors include Clarios, GE Healthcare, the Richard and Ethel Herzfeld Foundation, and the Rockwell Automation Charitable Corporation.


Are you interested in supporting Catalyst Grants? contact Jessica Silvaggi, jessica@uwmrf.org.

Since the program's inception, Catalyst projects have earned close to a seven-fold return in follow on grants and investments. This year five exciting UWM projects will receive $50,000 each to kickstart research related to drug discovery, breast cancer treatment, solar energy, infrastructure safety, and cybersecurity.

 

The projects listed below will be led by a combination of new and seasoned faculty members and their graduate students.

Using Advanced Computer Models to Find New Treatments for Skin Disease & Leukemia Dr. Arjun Saha, Dept. of Chemistry and Biochemistry


Dr. Saha’s project aims to revolutionize the understanding and targeting of protein-protein interactions (PPIs) in diseases. By combining machine learning algorithms with quantum chemistry and molecular dynamics, this research seeks to design small molecules that can modulate PPIs, providing new avenues for drug discovery in cancer and neurodegenerative diseases.

Identifying Breast Cancer-Fighting Proteins from Healthy Cells Dr. Qingsu Cheng, Dept. of Biomedical Engineering


Dr. Cheng's team is investigating proteins naturally secreted by human cells that inhibit the growth of triple-negative breast cancer (TNBC) cells. Using organoids derived from patient tumors, the goal is to identify proteins that can be developed into small molecule drugs, offering a cost-effective treatment for this aggressive cancer.

Developing Low-Cost Materials for Better Solar Panels

Dr. Nikolai Kouklin, Dept. of Materials Science and Engineering; Dr. Konstantin Sobolev, Dept. of Civil and Environmental Engineering


This project focuses on developing zinc oxide phosphate films for use in solar cells and other optoelectronic devices. The researchers aim to overcome current material challenges in solar energy, offering a cost-effective and scalable alternative that enhances efficiency and environmental sustainability.

Creating a Device to Safely Test Anchors in Concrete Structures Dr. Jian Zhao, Dept. of Civil and Environmental Engineering; Dr. Nathan Salowitz, Dept. of Mechanical Engineering


This research team proposes a "smart cap nut" to detect defects in adhesive anchors used in concrete structures. By generating and measuring micro vibrations, this device aims to improve safety and reliability in construction, addressing a critical need for nondestructive testing methods.

Improving Cybersecurity for Advanced Manufacturing Systems Dr. Zhen Zeng, Dept. of Computer Science


Dr. Zeng’s team plans to create a large language model-assisted threat modeling system to enhance cybersecurity in complex advanced manufacturing systems. By automating repetitive tasks and integrating threat intelligence, this tool seeks to significantly reduce the time and effort required for threat modeling, improving the security posture of organizations.

These projects exemplify the University’s commitment to fostering research that addresses critical challenges and drives innovation. The Catalyst Grant Awards will support these researchers in bringing their transformative ideas to fruition.

Panther Partner Spotlight

Rani ElHajjar - Pioneering Solutions in Composite Material Analysis

Tell us about your main area of expertise.


My focus is in nondestructive analysis of strain and stress in polymer-based composite materials. These materials are becoming increasingly popular across various industries due to their lightweight nature, corrosion resistance, and cost-effective manufacturing. However, the complexity and variability in the manufacturing process of polymer composites can lead to less reliability in the final structure compared to traditional materials like metals.

 

My work involves using advanced full field measurement techniques, which offer a comprehensive view of strain and stress distribution across the entire material. This approach helps identify discrepancies between expected and actual performance, guiding necessary adjustments in the manufacturing process or design to prevent failures. 


What are some ways you and UWM can help companies? 


I am often called upon to help companies manage the complexities of composite materials testing as they relate to production challenges. Many companies face difficulties in conducting specialized tests and navigating the extensive array of testing requirements, particularly if they have limited R&D capabilities.

 

At UWM, we provide access to specialized fixtures recommended by ASTM standards for comprehensive testing. We also have the unique capability to both make composites and subject them to rigorous destructive and non-destructive testing across various environmental conditions. This integrated approach allows us to not only help companies assess the performance and durability of their materials but also to optimize production processes and mitigate potential issues early on.

 

Give us a few examples of how you have helped companies in the past.


I've had the opportunity to work with various companies, both large and small, on fascinating projects involving composite materials. At SpaceX, for instance, I was involved in analyzing the quality of composite spacecraft parts they manufacture. I contributed by writing a book titled Effects of Defects in Composite Structures, which they still use. The book details potential issues from material arrival to assembly and curing, and provides procedures for managing these defects. My role included setting up documentation and processes to control and assess the severity of these defects. We conducted extensive testing to understand how different types of defects affected the structural properties of composite materials, which are inherently more variable than metals. The same composite material was used to make about 150 parts. Using labor-saving full field analysis techniques, we measured over 50 defects in the material that needed to be addressed.

Expertise Highlights:

How can Rani help you?

Field of Interest:

-Polymer-Based Composites

  • Defect analysis and development of new structural materials

-Experimental Mechanics

  • Composites
  • Smart materials
  • Defects

-Fracture Mechanics

  • Effects of defects in composite structures

-Full Field Non-Destructive Testing Methods

-Testing Composite Structures for Safety

-Developing Composite Materials for Zero Greenhouse Emissions


Skills:

  • Mechanical behavior of materials
  • Mechanical testing
  • Mechanics of materials
  • Computational structural mechanics
  • Stress analysis
  • Fracture mechanics
  • Fracture and failure analysis
  • Experimental mechanics
  • Structural engineering
  • Composite materials
  • Damage mechanics
  • Composite structures
  • Multiscale modeling
  • Laminated composites
  • Composite cure simulation


Partnering Ideas:

  • Improve build reliability on composite fabricated parts to reduce failure risk
  • Characterize new composite parts or structures at multiple scales, from fiber and matrix up to the structural level components


Resources for Partnering:

-Hardware

  • Composite fabrication
  • Environmental testing
  • Digital image correlation
  • Acoustic emission
  • Strain measurements
  • Mechanical testing

-Software

  • Cure simulation
  • Matlab
  • Mathematica
  • ANSYS


Please contact Brian Walsh, Senior Technology Commercialization Manager to connect with Rani ElHajjar.

In the News

TCare, a UWMRF startup, originally founded by Dr. Rhonda Montgomery, Helen Bader School of social welfare was featured in Forbes magazine.


There are over 53 million unpaid family caregivers in the U.S., who face significant challenges balancing care duties with full-time jobs, often leading to burnout and negative health outcomes. The TCARE system, developed with input from the University of Wisconsin-Milwaukee, helps mitigate these issues by addressing the identity shifts caregivers experience, thus reducing burnout and promoting wellbeing.


High-Tech With A Human Touch: How AI Can Help Caregivers Reduce Stress (forbes.com)

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