-36 of the 56 participants completed the protocol. All participants were Caucasian; 1/3 were women. The mean office entry BP was 161/98 mm Hg.
-In aggregate, the magnitude of BP reduction (16/10 mm Hg) among all individuals was similar after exposure to to each class.
-With respect to a given patient's response by anti-hypertensive class, differences in agent efficacy often varied by 50% or more.
-Figure and table: As a result, BP control (
<140/90 mm Hg) was achieved nearly twice as often with a particular anti-hypertensive ("best class") compared to the remaining classes ("any class").
-Shortcomings: The studied suffered from an open label design, a small and homogeneous population, and a lack of clear randomization.