PRISE Center and Learning Health Systems E-STAR Center Introduce A New Implementation Science Workshop

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The PRISE Center and the Learning Health System (LHS) Embedded Scientist Training and Research (E-STAR) Center have jointly developed a new learning health systems workshop entitled "Using Implementation Science (ImS) to Advance Learning Health Systems".

The workshop aims to provide participants with an overview of core LHS and implementation science principles, an overview of the application of LHS methods to patient-centered outcomes research (PCOR), and an opportunity to learn how to translate LHS concepts to their real-world work/research settings.

The 2-day workshop will be held online via Zoom, and led by a team of learning health systems and implementation science experts from the PRISE and E-STAR centers. Training will be comprised of a combination of didactic presentations and interactive small-group sessions.

The workshop has garnered significant interest from both the UCSF community and external partners. Some topics covered in the workshop include: Introduction to Learning Health Systems, Introduction to Implementation Science, Applying Program Evaluation Methods from ImS to the LHS Context, and Rapid Qualitative Approaches to LHS Implementation.

While registration is closed, interested participants can email the PRISE Center Program Manager, Tiese Etim-Inyang [tiese.etim-inyang@ucsf.edu] to learn about future workshop opportunities.

PCORI 2025 & Beyond Webinar

Session Title: Driving Research Innovation

Date and Time: Tuesday, Jan. 21 at 2 pm EST

Join Executive Director Nakela L. Cook, M.D., MPH, and other PCORI leaders to learn how PCORI is driving research innovation in 2025.

Please register for this webinar at the link below

Applications are now open for the 2025/2026 PRISE T32 cohort.

The Partnerships for Research in Implementation Science for Equity in Heart and Lung Diseases (PRISE-HL) T32 program aims to provide support to outstanding postdoctoral scholars with interdisciplinary training in implementation science and health equity approaches to help transform the uptake and delivery of evidence-based interventions for heart and lung diseases in clinical and community settings. 

We have 4 open positions in the PRISE Center-sponsored T32, to start on or before July 1, 2025. The location for this postdoc position is the University of California, San Francisco (UCSF) or the University of California, Irvine (UCI). The position may be fully remote or hybrid depending on the research scope. 

One-year training slots are available on a competitive basis to trainees proposing implementation science research in NHLBI priority areas (heart, lung, blood, and sleep disorders), focusing on health disparities. We are accepting applications until March 1, 2025. 

Please click the link below for application details and requirements. Kindly share this link with your networks, and reach out to the PRISE Program Manager [tiese.etim-inyang@ucsf.edu] if you have any candidates who would be a good fit for the PRISE T32 program.

Patient-Centered Outcomes Research Institute (PCORI) Engagement Awards

Through the Eugene Washington Engagement Award, PCORI is awarding research support funds to projects that encourage active, meaningful involvement of patients, families, caregivers, and the broader health and healthcare community as integral members of the patient-centered comparative clinical effectiveness research (CER) enterprise. Links to the PCORI announcements are included below.

PFAs Open Jan 16, 2025

Letter of Intent due April 1, 2025 (5 pm EST)

Applications due July 10, 2025 (5 pm EST)

NIH Climate Change and Health Initiative Funding Notice

The NIH Climate Change and Health Initiative (CCHI) is seeking proposals for implementation science studies that explore barriers and enablers to adopting, implementing, scaling, and sustaining effective interventions to prevent or reduce the health impacts of climate change in the U.S. and globally. This notice of special interest (NOSI) expires in 2028. Check the notice (linked below) for details.

Notice of Special Interest: Implementation Science for Climate Change and Health

NIH Dissemination and Implementation Research in Health Funding Announcements

These FOAs encourage investigators to submit research grant applications that will identify, develop, test, evaluate and/or refine strategies to disseminate and implement evidence-based practices into public health, clinical practice, and community settings. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. These FOAs expire in 2028. Check the notices (linked below) for details.

R01 Research Project Grant [next submission date: February 5, 2025]

R21 Exploratory/Developmental Research Grant [next submission date: February 16, 2025]

R03 Small Grant Program [next submission date: February 16, 2025]

NIH Prevention Research Funding Opportunities

NIH funding opportunities in the areas of time-sensitive health research, women’s health, and HIV prevention.

Time-Sensitive Opportunities for Health Research (R61/R33 Clinical Trial Not Allowed)

New expiration date: March 2, 2025 

Notice of Special Interest: Women’s Health Research

Expiration date: November 5, 2027

Development & Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Expiration date: May 8, 2027

Lam-Hine T, Thakur N, Saperstein A, Mujahid MS, Rehkopf DH. Asthma Prevalence in the Disaggregated Multiracial Population of California. JAMA Netw Open. 2024 Dec 2;7(12):e2449588. doi: 10.1001/jamanetworkopen.2024.49588. PMID: 39652351; PMCID: PMC11629126.

Velloza J, Mehtani NJ, Hickey MD, Imbert E, Appa A, Riley ED. A Review of Implementation Strategies to Enhance PrEP Delivery for People Experiencing Housing Insecurity: Advancing a Multifaceted High-Touch, Low Barrier Approach. Curr HIV/AIDS Rep. 2024 Nov 22;22(1):4. doi: 10.1007/s11904-024-00714-z. PMID: 39576385; PMCID: PMC11584499.

Doshi B, Luna I, Quesada R, Garcia ME, Fernandez A, Khoong EC. The Impact of Language Discordance on Acquiring Broad Social History: A Qualitative Study of Patients, Clinicians, and Interpreters. J Gen Intern Med. 2024 Dec 13. doi: 10.1007/s11606-024-09234-3. Epub ahead of print. PMID: 39672983.

Martin M, Baisey T, Skinner S, Ly L, Slown K, Harter K, Nguyen OK, Steiger S, Suen LW. Early Results of Implementing Rapid Methadone Titration for Hospitalized Patients: A Case Series. J Gen Intern Med. 2025 Jan 13. doi: 10.1007/s11606-024-09341-1. Epub ahead of print. PMID: 39804553.

Katamba A, Mochizuki T, Nalugwa T, Nantale M, Oyuku D, Nabwire S, Babirye D, Musinguzi J, Nakawesa A, Nekesa I, Turyahabwe S, Joloba M, Dowdy DW, Moore DAJ, Davis JL, Shete P, Adams K, Reza T, Fielding K, Cattamanchi A. Impact of a multicomponent strategy including decentralized molecular testing for tuberculosis on mortality: planned analysis of a cluster-randomized trial in Uganda. EClinicalMedicine. 2024 Nov 26;78:102953. doi: 10.1016/j.eclinm.2024.102953. PMID: 39659443; PMCID: PMC11629260.

Spinelli MA, Bisom-Rapp E, Heise MJ, Camp C, Appa A, Liu AY, Sassaman K, Shiels M, Mayorga-Munoz F, Chimezie A, Nguyen J, Oskarsson J, Gandhi M. High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population. Clin Infect Dis. 2024 Nov 1:ciae531. doi: 10.1093/cid/ciae531. Epub ahead of print. PMID: 39484783.