Reminder to reference the Office of Research Services (ORS) dedicated web page for updates during the Federal Government Shutdown. The page includes FAQs about stopping work, submitting proposals, and other topics relevant to the research community. Importantly, for the duration of the funding lapse, applicants should continue to submit applications in accordance with the due dates outlined in the Notices of Funding Opportunities.

Penn Medicine-Protected AI Tool for Your Everyday Use


Introducing Microsoft Copilot Chat at Penn Medicine, a secure, LLM-powered chatbot to replace Penn AI Chat. It's a violation of HIPAA and Penn Medicine policy to share patient or proprietary Penn Medicine data on public AI tools. Instead, use Copilot Chat to ensure enterprise data protection for AI tasks and inquiries. Sign in below with your Penn Medicine credentials or download the app on a Penn Medicine-managed mobile device.


Get started with Copilot Chat

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*You must be logged into the Penn Medicine network to access this link. 

Research Security Training Requirement


Both NIH and NSF have announced new requirements for the completion of Research Security training for PIs and Senior Key Personnel starting in October 2025. The training should be completed at the time of proposal. For more information about Research Security Training, including federal agency timelines for training requirements, please visit the Office of Research Services' dedicated page below.


Please direct inquiries to: Missy Peloso or Jessie Buchanan


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Disclosure of Foreign Components to Federal Funding Agencies


In order to assist Penn investigators in complying with recent federal requirements for the disclosure of foreign components, the Office of the Vice Provost for Research created a dedicated website featuring guidance and key information regarding these requirements. See below for details.


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Funding Opportunity for Sarcoidosis research


Letter of Intent deadline: October 23, 2025

Full application: January 19, 2026


The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in collaboration with the Ann Theodore Foundation, is launching the next cycle of a grant program focused on sarcoidosis. The program intends to fund up to six grants this cycle, awarding up to $575K over two years to support research focused on the basic science of sarcoidosis. Please see the RFP below. We will be holding a virtual informational session over Zoom on Thursday, October 9, 2025, at 3p ET.


Please direct inquiries to: Sarcoidosis Grant Team


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Funding Opportunity for FTD research


Letter of Intent deadline: November 3, 2025

Full application: February 9, 2026


The Kissick Family Foundation Frontotemporal Dementia (FTD) Grant Program is now accepting letters of intent for its third cycle. The RFP calls for basic science or early-stage translational research projects that focus on building a fundamental understanding of sporadic FTD. The Kissick Family Foundation, with guidance from the Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), welcomes research proposals that request up to $500k over two years.


Please direct inquiries to: SPARC Team


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Pennsylvania Department of Health Research to Cure & Prevent Type 1 (Juvenile) Diabetes


Letter of Intent deadline: November 3, 2025

Full application: November 24, 2025


The Pennsylvania Department of Health issued a Request for Applications on September 24, 2025. This grant is titled "Research to Cure and Prevent Type 1 (Juvenile) Diabetes” and can be found at the below link on PA-eMarketplace. Please note the following information: * The grant term is anticipated to run from July 1, 2026 through June 30, 2030 * $237,955 is available for award * One award is anticipated to result.


Please direct inquiries to: PA DOH


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CIFAR Global Scholars Program


Submission deadline: November 5, 2025


CIFAR is now accepting applications for the 2026-2028 cohort of the CIFAR Global Scholars Program. This unique initiative provides junior faculty the opportunity to develop and lead high-risk, high-reward interdisciplinary research, expand their professional networks and receive focused leadership training in their pivotal first years as independent investigators.


Please direct inquiries to: CIFAR


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Upcoming Research Funding Deadlines at the American Heart Association


Details have been set for the following American Heart Association research programs. See each program’s web page for specifics. Before beginning an application, review the eligibility and requirements that apply to all Association research awards on the Application Resources page. Also, the Association continues to seek proposals related to Sudden Cardiac Arrest.


Strategically Focused Research Network (SFRN) on Earlier Detection and Delaying Progression of Valvular Heart Disease - October 29, 2025


Career Development Award - December 2, 2025


Innovative Project Award - December 10, 2025


Using AHA Get With the Guidelines® Research Data in the Precision Medicine Platform to further address current gaps in understanding of CVD - January 15, 2026

Waldenstrom Macroglobulinemia (WM) Research Request for Proposals 


Letter of Intent deadline: November 28, 2025


In partnership with our friends at the International Waldenstrom Macroglobulinemia Foundation (IWMF), Blood Cancer United is pleased to announce the launch of the 2026 WM Research RFPs. For 2026, IWMF is seeking proposals for research and clinical studies that will deliver therapeutic benefits for WM patients within the next 3–5 years. Grant amounts range from $250K–$1M over 2–4 years, with a separate award to support young investigators.


Important: Because of particular contractual requirements, any faculty interested in applying should first seek approval by emailing Michael Ostap, Chief Scientific Officer, and Robert Vonderheide, Director of the Abramson Cancer Center. Careful consideration of proprietary information or potential IP from the proposed work is required; if there are specific questions about IP, please contact Benjamin Dibling, Managing Director of the Penn Center for Innovation.


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PSOM Limited Application - Blavatnik National Awards for Young Scientists


Submission deadline: October 22, 2025


The University has been invited to nominate one faculty member for each of the three disciplinary categories: Life Sciences, Physical Sciences & Engineering, and Chemical Sciences. The Office of the Vice Provost for Research (OVPR) is managing the final candidate review and selection process.


Please direct inquiries to: Kaitlyn Hagarty


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PERFORM-KUH TL1 - Next Application Round


Submission deadline: November 3, 2025


The Philadelphia Program for Mentored Research Training in Kidney, Urologic, and Hematologic Diseases (PERFORM-KUH) institutional network award would like to announce the next round of PERFORM-KUH grant applications!


*PLEASE NOTE* Two post-doc slots recently became available and will be admitted by January 1! Please follow the link below for application details.


Please direct inquiries to: Adam Mussell


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PSOM Limited Application - W. M. Keck Research Program in Medical Research and Science & Engineering (December Cycle)


Submission deadline: November 18, 2025


The University has been invited to submit one proposal for each of the two W. M. Keck Research Program grant categories: (1) Medical Research and (2) Science & Engineering. The Office of the Vice Provost for Research (OVPR) will oversee the final proposal review and selection process.


Please direct inquiries to: Kaitlyn Hagarty


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PSOM Limited Application - Mathers Grant Program (Spring Cycle)


Submission deadline: December 5, 2025


The University has been invited to nominate three candidates for the Mathers Grant Program. The Office of the Vice Provost for Research (OVPR) is managing the final candidate review and selection process. Each school within the University may submit the names of up to three candidates.


Please direct inquiries to: Kaitlyn Hagarty


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Penn Institute for RNA Innovation Fall 2025 Pilot Grant


Submission deadline: October 27, 2025


The Penn Institute for RNA Innovation seeks to support RNA-related basic, translational and clinical research. Towards that goal, the Institute is requesting applications for its Pilot Grants Program for Fall 2025. Pilot funding will provide initial support to establish proof of concept or extend findings to enable extramural funding and publications in the future.


Please direct inquiries to: Jill Agolino


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Health Tech Accelerator Call for Proposals


Submission deadline: November 5, 2025


We’re excited to share that the 2025-2026 Call for Proposals for our Health Tech Accelerator is now open! This is a fantastic opportunity for innovators to receive up to $75,000 in funding to bring their healthcare solutions to life. We would greatly appreciate your support in sharing this opportunity with your network.


Please direct inquiries to: Gloria Easley


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Penn LDI Research Initiative on Improving Primary Care for Older Adults


Submission deadline: November 10, 2025


The new Penn LDI Research Initiative on Improving Primary Care for Older Adults will fund rapid-turnaround high-impact research projects that will have a meaningful and measurable impact on value-based primary care and other alternative delivery models focused on older adults. This program is made possible by a generous gift from CenterWell, a part of Humana.


Please direct inquiries to: Caleb Hearn


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Penn LDI Small Grants Program 2025 Request for Proposals: Expanding Access to Health Care


Submission deadline: November 10, 2025


Penn LDI requests proposals for small research grants focusing on expanding access to health insurance and health care. The goal of this request is to expand research activity and expertise at Penn focused in this area, leading to the expansion of access to health insurance and/or health care.


Please direct inquiries to: Traci Chupik


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2025 LDI-Penn Medicine Research Laboratory Request for Proposals


Submission deadline: November 10, 2025


Penn LDI and Penn Medicine announce the 5th Annual Request for Proposals for the LDI–Penn Medicine Research Laboratory. This year, the Research Lab solicits proposals that improve the effectiveness, efficiency, safety, and experience of care delivery at Penn Medicine, with a special focus on how generative artificial intelligence (AI) can optimize health care delivery.


Please direct inquiries to: Traci Chupik


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Penn CFAR Developmental Pilot Grant Program RFA


Submission deadline: November 14, 2025


The Penn Center for AIDS Research (Penn CFAR) invites Pilot Grant applications. Projects can be in any areas of HIV/AIDS supported by the U.S. National Institutes of Health including clinical, basic, behavioral and implementation science research.


Please direct inquiries to: Cherylann McGee


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Penn Clinical and Translational Science KL2/K12 Mentored Career Development Award


Submission deadline: December 1, 2025


ITMAT Education is pleased to announce a request for applications to the Penn CTSA KL2/K12 Mentored Career Development Award Program. This award seeks to support early career faculty focused on Clinical and Translational Science (CTS). Application Deadline: December 1, 2025 Anticipated Appointment: July 1, 2026 Visit the link below for program, eligibility, and application information.


Please direct inquiries to: Megan Maxwell


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ITMAT Education NIH CTSA TL1/T32 Training Programs in Clinical and Translational Science


Submission deadline: December 1, 2025


ITMAT Education offers funded educational programs via the NIH CTSA TL1/T32 Grant for Predoctoral Students (MD, VMD, DMD and PhD students) and Postdoctoral Trainees (GME Trainees and Postdoctoral PhDs). Applications due December 1, 2025 for July 2026 admission and appointments. Visit the weblink below for more information.


Please direct inquiries to: Megan Maxwell


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Roybal Center on Behavioral Economics and Health Funding Program 


Submission deadline: January 5, 2026


The Roybal Center on Behavioral Economics and Health seeks applications that: - Explore mechanisms of behavior change - Generate knowledge at an appropriate stage that contributes to effective and scalable interventions - Incorporate one or more of the Penn P30 themes: Design thinking, digital platforms, and dynamic adaptation - Have focus on Food is Medicine (preferred) and cardiovascular risk reduction Total costs: $200K Duration: 18 months, with an anticipated project start date of June 1st.


Please direct inquiries to: Joelle Friedman


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