Mitegen October Newsletter
Paper - findMySequence: A Neural-network-based-approach for Identification of Unknown Proteins in X-ray and Cryo-EM
Image Source: Chojnowski, et al. (2021). findMySequence: A Neural-network-based Approach for Identification of Unknown Proteins in X-ray Crystallography and Cryo-EM. IUCrJ volume 9, part 1 ISSN: 2052-2525
This paper in IUCrJ by Chojnowski, et al., presents "an automated pipeline for the identification of protein sequences from cryo-EM reconstructions and crystallographic data." While there are several components in the pipeline, a key element "is the computer program findMySequence that identifies the most plausible protein sequence in a sequence database, given an electron-density map or cryo-EM reconstruction and a main-chain-only model."
New Product - Nanosoft Hybrid Cryo-EM Grid Boxes
The Nanosoft Hybrid Cryo-EM sample storage grid box features dedicated pockets for both unclipped grids and autogrids. Available in 6 colors and with randomized serial numbers on the side of the grid box for easier organization, traceability and sample tracking. You have your choice of grid boxes with or without lids.
Paper - New System for Archiving Integrative Structures
In this paper at Acta Crystallographica Section D by Vallat, et al., learn about PDB-Dev, "a standalone system developed for archiving integrative structures and making them publicly available. The data standards and software tools that support PDB-Dev are described along with the new and updated components of the PDB-Dev data-collection, processing and archiving infrastructure."
Our In Situ-1 Plates on Twitter
We greatly appreciate our customers, partners and collaborators sharing their feedback concerning our products and how it impacts their research.

This Twitter post is by Nemanja Vuksanovic, a Postdoctoral Fellow in Chemistry at Boston University. You can learn more about the research Nemanja is involved with by visiting his profile on Publons.
Learn About Our In Situ-1 Plates
The In Situ‐1™ plate enables crystallography researchers to easily grow, transport and screen crystals of their targets.

Key benefits of In Situ‐1™ plates include:

  • Increase hit rates with controlled kinetics
  • Safely ship crystals in the plate
  • Collect XRD data without harvesting
New - Overstock Product Department
Occasionally we develop an oversupply of products. When this occurs we like to provide our customers a chance to take advantage of this oversupply.

Overstock items this month include cryogenic storage dewars, cryo-EM grids and crystallization plates.
Upcoming Events
At MiTeGen, we sponsor numerous events, conferences, workshops and symposiums throughout the year. These events include fields such as structural biology, crystallography, cryo-EM, beamline research and more. We believe in supporting researchers and our industry. Listed below are two upcoming events you might find interesting.
The Biostruct Africa workshop is April 25th to 28th. Provides hands-on training in structural biology for sustainable development in Africa. Includes X-ray crystallographic and cryo-EM remote data collection and structural determination. We are sponsoring this workshop.
ACA Summer Course 2022 will be held June 12th to 18th. Course will instruct attendees in single-crystal chemical crystallography and powder diffraction techniques, as applicable to small molecule studies. We are sponsoring this course.
Looking For More Events, Workshops and Conferences
If you are looking for more events visit our events page. It lists conferences, workshops, symposiums, user meetings and more.

Topics include structural biology, material science, crystallography, cryo-EM, beamline research and more.
Industry Resources and News
Here is a small selection of industry resources and news for your browsing.

  • The Living Systems Institute (LSI) at University of Exeter is accepting applications for its PhD Program. Research ranges from organisms to atoms and also include cryo-EM - Learn More
  • Learn about experiments conducted at the MAX IV Laboratory via the Swedish Research Council's podcast - Learn More 
  • The Astbury Biostructure Lab (University of Leeds) is partnering with several large institutions to offer training in cryo-EM. Courses include sample prep, data collection and more - Learn More
  • #LightSourceSelfies is a feature at that showcases scientists and engineers who hold a range of positions at light sources located across Europe, Asia, Australia, North America, and South America - Learn More
  • ScientiFika is an initiative by MAX IV, Lund University that aims to share knowledge and stimulate enthusiastic discussions on synchrotron research and methods developed at MAX IV. Features discussions most Mondays in either a virtual or live format - Learn More
  • One World Cryo-EM is a seminar series for the discussion of algorithms, computational methods and mathematical problems in cryo-EM. Offered online every other Wednesday - Learn More
  • The Ludo Frevel Crystallography Scholarship is accepting donations. This scholarship is designed to encourage promising graduate students to pursue crystallographically oriented research - Learn More 
  • The Diamond Light Source 2022 Summer Placement Program is now accepting applications. The program is designed for undergraduates to gain experience at a synchrotron - Learn More
  • MDPI Crystals is soliciting submissions for its upcoming special issue, Crystalline Phases Under Extreme Conditions. This issue will "address the broad ground in the application of extreme-conditions crystallography, but also to introduce readers to the most recent scientific developments." - Learn More
  • EMBL Imaging Center has an open call for users. This is the first call and offers researchers from academia and industry rapid access to the most advanced microscopy technologies available - Learn More
  • AlphaFold2: Highly accurate protein structure prediction. "AlphaFold2 leverages multiple sequence alignments and neural networks to predict protein structures" - Learn More
Industry Jobs
Searching for a new job? Interested in knowing what positions labs and facilities are offering? Then visit our jobs board on which we list recent industry job offerings.

And remember, if you have an industry relevant job, we are happy to list it on our jobs board.
Have your lab be the first to know. Follow us on social media!