Impact of Obesity on Prostate Cancer Recurrence After Radiation Therapy
You can probably guess the answer to this one ....
While there is definite evidence that obesity is associated with more aggressive prostate cancer at diagnosis, there are less data on the impact of obesity on recurrence rates after men undergo treatment for prostate cancer. A recent study shed more light on this question.
Researchers from Fox Chase Cancer Center in Philadelphia, PA recently published a study which investigated whether BMI* was associated with a man's risk of prostate cancer recurrence after treatment with radiation therapy. In this study, 1,442 men with localized prostate cancer were treated with intensity modulated radiation therapy or IMRT (the most advanced external beam radiation treatment technique) between 2001 and 2010. The median follow up in this study was about 4 years and the median radiation dose was 7800cGy. One third of men had BMIs greater than 30, which is considered obese. Results showed that increasing BMI was associated with increased risk of PSA recurrence, distant metastasis rate, cause specific mortality and overall mortality.
The Bottom Line: The heavier you are, the higher your risk of cancer recurrence after prostate cancer treatment. Another good reason to stick with those New Year's resolutions!