Pre-Screening Agents, Meeting, Article - Crystallography & Cryo-EM Aid Hallucinogen Research, Survey, List Your Job/News/Event, Virtual Meeting Offer & More |
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Introducing Polyvalan Crystallophore Pre-Screening and Experimental Phasing Agents |
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We are now offering Polyvalan's new generation of Crystallophores Lanthanide based complexes. Crystallophores TbXo4-02 (new Terbium generation) and LuXo4-01 (Lutetium 1st generation) are unique pre-screening and phasing agents.
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When used as pre-screening agents they can be useful for:
- Obtaining crystals from new crystallization conditions
- Inducing different crystal forms
- Improving crystal quality and reproducibility
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When used as phasing agents they can be useful for:
- Overcoming the tedious and time-consuming work of seleno-methionine labeling or of heavy atom incorporation
- Serving as powerful phasing agents for native crystals using SAD or MAD methods.
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Learn More and Ask Questions About Polyvalans Crystallophore Agents |
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On October 21st at 11am EST we will have a Zoom Meeting during which a representative from Polyvalan will provide in-depth details and answer your questions about Crystallophore Pre-Screening and Experimental Phasing Agents. You will be able to ask your questions beforehand and during the meeting. The recorded version of this meeting will be made available to all attendees. |
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Article - Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor |
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This article at Cell by Byran L. Roth (et al.) seeks to understand better how psychedelics mediate their actions, whether under therapeutic and hallucinogenic conditions.
They do this by, "gaining molecular insights into psychedelic actions, they determined the active-state structure of HTR2A bound to 25-CN-NBOH—a prototypical hallucinogen—in complex with an engineered Gαq heterotrimer by cryoelectron microscopy (cryo-EM).
They also obtained the X-ray crystal structures of HTR2A complexed with the arrestin-biased ligand LSD or the inverse agonist methiothepin."
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Image Credit - Cell (2020); Bryan L. Roth (et al.) https://doi.org/10.1016/j.cell.2020.08.024 |
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Survey Questions - Please Share Your Insights |
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We are asking for your input on three short survey questions. Please share your insights, experience and expertise.
These questions include:
- What techniques are you using in your research
- What events, workshops or conferences you have or are attending
- What purchasing guidelines are you or your lab subject to
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Given the importance of structural biology and related fields, there are numerous job openings available. Listed below are some of the latest ones we are aware of:
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The Institute of Cancer Research has a postdoctoral position available involving in X-ray crystallography, fragment-based screening and structure-based drug design and will be responsible for protein expression, purification, crystallisation, structure determination and structural analysis of protein-ligand complexes from one of the CTU’s drug discovery programmes - Learn More
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Stony Brook University is seeking a talented, motivated and highly interactive individual to manage their cryo-EM facility. The facility house’s a Thermo Fisher Scientific, 200kV Talos Arctica with a Falcon 3EC direct electron detector, along with all standard equipment for sample preparation - Learn More
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The Protein Structure and Biophysics department at UCB has a Senior Scientist - Cryo EM position available - Learn More
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The lab of Professor Vlad Pena has a Post-doctoral Training Fellow - Cryo-EM Structural Biology position available - Learn More
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Ghosal Lab at University of Melbourne has a postdoc for a PhD student available for investigating the structure and function of bacterial and viral molecular machines that are important for pathogenesis using integrative approaches including cryo-ET, CLEM and various cell biology and biochemical methods - Learn More
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EMBL Grenoble is looking for a postdoctoral scientist to play a key role in the exploitation of the upgraded MASSIF-1 beam line at the ESRF with a focus on the development of innovative approaches to automated crystallography and ligand screening - Learn More
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The Leschziner lab at the University of California San Diego is seeking postdoctoral fellows to join our project on LRRK2 and Parkinson’s Disease - Learn More
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The Glass Lab at Albany College of Pharmacy and Health Sciences (ACPHS) has full-time NIH funded postdoctoral positions available for Ph.D. scientists with experience in biochemistry, enzymology, crystallography, NMR spectroscopy, or molecular biology - Learn More
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The Bajic Laboratory at Icahn School of Medicine at Mount Sinai is looking for an enthusiastic post-doctoral fellow with experience in cryo-EM to join their group - Learn More
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List Your Job, Internship or Related Position Here! |
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Do you have a job opening, internship or related position at your lab or facility? Would you like to have it listed in our newsletter?
Use the button below to learn more about how you can have it listed in our newsletter. In addition, tag us on Twitter or Instagram and we will share it there too! There is NO charge for this, we simply want to help you!
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Industry Resources and News |
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Here is a small selection of hand picked industry resources and news for your browsing.
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Do You Have Industry News? |
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Do you have industry news you'd like to share? Examples include recently published papers, new lab openings or expansion and more.
Use the button below to learn more about how you can have it listed in our newsletter. In addition, tag us on Twitter or Instagram and we will share it there too! There is NO charge for this, we simply want to help you!
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Learn First-Hand About Tools To Improve Your Research |
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If you need more information concerning our tools for crystallography, cryo-EM or beamline research, why don't you consider a Zoom virtual meeting with us.
You can use our Zoom virtual meetings to gain more in-depth product information including a live display of them. In addition we can answer your questions and learn about the challenges you face in your research and the solutions we offer for it.
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We are sponsoring the 2020 inaugural symposium of the Geneva cryo-electron microscopy center otherwise known as Cryogenic 2020. Features speakers on advances in electron microscopy – single particle analysis, electron diffraction & cellular tomography. |
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Do You Have An Event You Need Sponored or Promoted? |
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Are you seeking sponsorship for a crystallography, cryoEM, or synchrotron related workshop, event, or meeting? We value and support these types of activities.
Sponsorship can be direct funding or in-kind promotional support such as a listing in our newsletter and on social media. Let's explore together!
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Have your lab be the first to know. Follow us on social media! |
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