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Anti-aging news for the two weeks ending March 23, 2016
QualityCounts.com Newsletter of March 23, 2016

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Magnesium ions show promise in slowing progression of Alzheimer's disease in mice  - Science Daily, 12/1/15 - "in mouse models of the disease oral administration of magnesium-L-threonate (MgT) alleviated cognitive decline by suppressing the Aβ deposition in amyloid plaques in an APH-1α/1β-dependent manner ... The good news about this work is that if it holds up in humans, magnesium is a common element that is readily available" - See Magtein at Amazon.com.

Magnesium levels vital to brain health as population ages - Science Daily, 11/4/13 - "the human brain begins shrinking after age 25. Structural changes and loss of brain synapses lead to rapid decline in cognitive health ... magnesium deficiency in adults may play a more important role in CI, and more seriously, Alzheimer's Disease (AD), than previously thought ... elevation of brain magnesium through dietary intake of magnesium threonate exerts substantial positive effects on brain synapes in a mouse model of AD, actually restoring aging brains to their youthful conditions ... the 'gold standard' of science, demonstrates that dietary supplementation of Magtein, patented magnesium threonate, can significantly enhance human cognitive functions and decrease symptoms of cognitive impairments ... We know that as we age our bodies naturally lose magnesium. For example, drinking coffee or caffeinated products increases the loss"  - See Magtein at Amazon.com.

Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model - J Neurosci. 2013 May 8;33(19):8423-41 - "Here, we investigated whether elevation of brain magnesium by the use of a recently developed compound, magnesium-l-threonate (MgT), can ameliorate the AD-like pathologies and cognitive deficits in the APPswe/PS1dE9 mice, a transgenic (Tg) mouse model of AD. MgT treatment reduced Aβ plaque and prevented synapse loss and memory decline in the Tg mice. Strikingly, MgT treatment was effective even when given to the mice at the end stage of their AD-like pathological progression ... Our results suggest that elevation of brain magnesium exerts substantial synaptoprotective effects in a mouse model of AD and may have therapeutic potential for treating AD in humans"  - See Magtein at Amazon.com.

Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial - J Alzheimers Dis. 2015 Oct 27;49(4):971-90 -  "Since brain atrophy during aging is strongly associated with both cognitive decline and sleep disorder, we evaluated the efficacy of MMFS-01 in its ability to reverse cognitive impairment and improve sleep ... We conducted a randomized, double-blind, placebo-controlled, parallel-designed trial in older adult subjects (age 50-70) with cognitive impairment. Subject were treated with MMFS-01 (n = 23) or placebo (n = 21) for 12 weeks and cognitive ability, sleep quality, and emotion were evaluated.  With MMFS-01 treatment, overall cognitive ability improved significantly relative to placebo (p = 0.003; Cohen's d = 0.91).  Cognitive fluctuation was also reduced.  The study population has more severe executive function deficits than age-matched controls from normative data and the MMFS-01 treatment nearly restored their impaired function, demonstrating that MMFS-01 may be clinically significant" - [Nutra USA] - See Magtein at Amazon.com.

Magtein Source Naturals, Inc. 180 Caps (667 MG)
by Threshold Enterprises
Health and Beauty ~ Release Date: 2015-11-19
List Price: $74.50
Our Price: $30.41
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