August 2018
The Research Communique
News from the Associate Dean for Research:
CCR * DLAM * Flow Cytometry Facility * Grants and Contracts * ORC * OTT * RIF * SRIC
Research-Related Committees: GRC, LACUC, RCC, RPC, and SCRIHS.
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Congratulations Research Award Winners
External research awards
Jeffrey Cozzens, MD, Department of Neurology, Resection of High Grade Glioma with 5-ALA Fluorescence ,  Memorial Medical Center Foundation, $30,832.

Erin Hascup, PhD , Department of Neurology, Glutamate Neurotransmission in Alzheimer's Disease Progression , NIH, $2,947,425.

Michael Neumeister, MD , Department of Surgery, New Antimicrobial Agents to Eradicate Infection and Sterilize Burn Wounds,  Memorial Medical Center Foundation, $46,332.

Amber Pond, PhD , Department of Anatomy,  Calcium Signaling in Skeletal Muscle Atrophy: A Novel Role for the ERG1aK+ Channel, US Dept of Defense, $249,115.

Vickram Ramkumar, PhD, Department of Pharmacology,  Oral Epigallocatechin Gallate (EGCG) for Treatment of Cisplatin Ototoxicity , National Institutes of Health, $1,880,916.

Grants & Contracts Announcements:
The Memorial Medical Center Foundation has awarded more than a half-million dollars in health-related grants for community and health-system initiatives – a record-breaking total for the foundation's grant program.

Twenty-six projects, totaling $576,345 received amounts ranging from $490 to $125,000. In addition to the two research awards listed above from MMC, seven additional non-research awards were given  to the following SIU School of Medicine faculty/clinicians. Read more...

Congratulations!

Andrzej Bartke, PhD, Internal Medicine, Equipment for aging dementia research, $5,000.
 
Karen Broquet, MD , Residency Affairs, SIUSOM Resident and Fellow Quality Improvement Project Competition , $1,950.
 
Jonathan dela Cruz, MD, Surgery, A pilot study evaluating leadership perception and use of required advanced trauma life support (ATLS) guidelines during trauma situations at MMC, $ 6,400.
 
Wendi El-Amin, MD , Office of Equity, Diversity, and Inclusion, Cultivating Health Equity Initiatives, $39,446.
 
Michael Neumeister, MD , Surgery, Annual Wound Care Symposium , $490.
 
Sameer Vohra, MD, JD , Office of Population Science and Policy, Rural Health Statewide Convenin g, $16,986.
 
Myto Duong, MD , Surgery, Newborn/Infant Simulation and Training , $48,805.             
SAVE THE DATE...
SIU Center for Clinical Research
Save the Date: Clinical Trials Course

Friday, November 2, 2018
8:30 – 4:00 pm
Memorial Center for Learning and Innovation (MCLI) - Room 3D
228 W. Miller St. Springfield, IL 62702
 
The program and content is designed to provide clinical research education with a primary focus on the administrative aspects of sponsored clinical trials (drug and device). The content will be useful to anyone involved in clinical research and will provide an introduction to clinical trial conduct, Good Clinical Practices (GCPs), and sponsor-investigator relationships. This course is offered on an ongoing basis and space is limited.

For more information, contact Eric Meyer at emeyer@siumed.edu

Summary: A team of researchers at SIU comprising of Drs. Ramkumar, Mukherjea and Rybak have discovered that transplatin (which qualifies for NME status with the FDA) may be used as a protective/therapeutic agent against toxicities related to cisplatin and other platinum-containing anti-tumor compounds without reducing the anti-tumor efficacy of these platinum-based treatments. Transplatin also has other protective effects relating to aminoglycosides, noise, and radiation, and may be effective in treating pain. The team has recently partnered with a 3rd party for-profit entity to engage in translational research activities to bring this therapeutic to market.

Issued 2/11/2014 as US Pat #8,648,114 and 2/2/2016 as US Pat #9,248,150

To read more about this invention or others from SOM, SIUC & SIUE, please visit: SIU System Available Technologies.
Don't forget to disclose your ideas to the Office of Technology Transfer to get them protected!

With more than 100 research laboratories at SIU School of Medicine and vibrant life science and biomedical engineering research communities at SIU’s Carbondale and Edwardsville campuses, SIU fosters important medical discoveries and innovations.

This evaluation disclosure form allows you, the inventor, to describe your technology, what makes it novel, and how you think it may be applied commercially. All you have to do is fill out this form and submit it to the Office of Technology Transfer to initiate the technology transfer process. Questions? Contact the Office of Technology Transfer at techtransfer@siumed.edu.
Two New Enhancements to Commons Research Performance Progress Report (RPPR) Module
There have recently been two new enhancements within eRA Commons to streamline and improve the Research Performance Progress Report (RPPR) process. First, institutional delegations for Interim RPPRs and Final RPPRs have been modified to align with the delegations that institutional users have specified for annual RPPRs. A PI may delegate initiation of any type of RPPR to a program assistant. Second, data fields for effort reporting are modified to enable use of decimals rather than requiring entry of a whole number. This will allow for more accurate reporting. 

If you have any questions regarding these changes, email grantspolicy@od.nih.gov.
SAVE THE DATE...
University of Illinois-Springfield and the SIU School of Medicine Research Colloquia
Sponsored by: UIS & SIU SOM

Friday, October 26, 2018
11:00 a.m.    
Robbins-Woerner Conference Room, Simmons Cancer Institute
(Lunch will be served.)

Please RSVP to Kristi Katcher ( kkatcher@siumed.edu ) by October 17, 2018.
SIU School of Medicine faculty have article published in the Journal: The Prostate
C ongratulations to five SIU School of Medicine faculty & their two collaborators on the recent publication of their article listed below to the journal: The Prostate.

Article title: A Prospective Study to Examine the Association of the Urinary and Fecal Microbiota with Prostate Cancer Diagnosis after Transrectal Biopsy of the Prostate Using 16sRNA Gene Analysis

Alanee S 1 , El-Zawahry A 2 , Dynda D 2 , Dabaja A 1 , McVary K 2 , Ka r r M 3 , Braundmeier-Fleming A 3 .

Author information
1 Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan.
2 Division of Urology, Department of Surgery, Southern Illinois University School of Medicine
3 Department of Medical Microbiology, Immunology, and Cell Biology, Southern Illinois University School of Medicine

Abstract Introduction
"There is accumulating evidence that variations in the human microbiota may promote disease states including cancer. Our goal was to examine the association between urinary and fecal microbial profiles and the diagnosis of prostate cancer (PC) in patients undergoing transrectal biopsy of the prostate." Read more...
Calendar
September 2018
9/5 - Clinical Research Coordinators Network meeting, QI vs Research , presented by Amber Fifer , 201 E. Madison St., First Floor, Island Bay Conference Room, 9:30 am, contact: Kristal
Adams at 217-545-7812, kadams@siumed.edu or Lori Miedwig at 217-545-4402,
  
9/17 - Concept Development Award FY2019 Cycle A disclosure deadline, contact Kerri Taylor at ktaylor37@siumed.edu .

October 2018
10/1 - Concept Development Award FY2019 Cycle A application opening date, contact Kerri Taylor at ktaylor37@siumed.edu .

10/3 - Clinical Research Coordinators Network meeting, IRB Training TBD , presented by Alisha Mirabile and Eric Meyer , 201 E. Madison St., First Floor, Island Bay Conference Room, 8:15 am, contact: Kristal Adams at 217-545-7812, kadams@siumed.edu or Lori Miedwig at 217-545-4402,

10/5 - New NIH R01 grant submission deadlin e, contact:  grants@siumed.edu .

 10/15 - Concept Development Award FY2019 Cycle A application closing date, contact Kerri Taylor at ktaylor37@siumed.edu .

10/16 - New NIH R03/R21 grant submission deadline, contact:  grants@siumed.edu .

10/26 - University of Illinois at Springfield & the SIU School of Medicine Research Colloquia, SCI Robbins-Woerner Conference Room, 11:00 am, contact: Kristi Katcher at kkatcher@siumed.edu .

November 2018
11/2 - Clinical Trials Course, MCLI Room 3D, 8:30 am - 4:00 pm, contact: Eric Meyer at emeyer@siumed.edu .

11/5 - Revised NIH R01 grant submission deadlin e, contact:  grants@siumed.edu .

11/6 - Clinical Research Coordinators Network meeting, Recruitment Strategies that have Worked for Me , presented by Barbara Lokaitis , 201 E. Madison St., First Floor, Island Bay
Conference Room, 8:15 am, contact: Kristal Adams at 217-545-7812, kadams@siumed.edu or Lori Miedwig at 217-545-4402, lmiedwig@siumed.edu .

11/16 - Revised NIH R03/R21 grant submission deadline, contact:  grants@siumed.edu .
Watch for the next issue of
THE RESEARCH COMMUNIQUÉ
to come in November 2018.
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