Are you planning on submitting a Letter of Intent for a future submission?

If so, please let the research team know!

Although the research team isn’t required to be directly involved in the letter of intent (LOI) process unless financial (budget) or investigator time commitment is included in the LOI, it is helpful for us to be notified when a letter of intent is submitted to a sponsor. Sometimes, a sponsor notifies a PI that they have been invited to submit a full proposal on a tight timeline for full submission. Having that submission on our radar can help us better support faculty with the proposal process.

If you have any questions, please feel free to reach out to

CPH Research, Doris Castellanos, Elizabeth Crolley, Erin Pyrek, Jeff Kurz, Krys Lynam.

Registration has opened for the 2-part Webinar Series on the NIH Data Management and Sharing Policy!

Webinar I: Understanding the New NIH Data Management and Sharing Policy 

Thursday, August 11, 2022 / 1:30 - 3:30 PM EDT

Learn about DMS policy expectations, the applicability of the policy, how to prepare a Data Management and Sharing Plan, and considerations for sharing data responsibly.

Webinar II: Diving Deeper into the New NIH Data Management and Sharing Policy 

Thursday, September 22, 2022 / 1:30 - 3:30 PM EDT

Take a deeper dive into topics including privacy protections for data from human participants and justifiable limitations on sharing data.

Note: you must register for each event separately

Description: The National Institute on Drug Abuse (NIDA) seeks to support clinical trials that will evaluate multi-level interventions for patients who are using long-term opioid therapy to manage chronic pain for whom risks of continuing opioid therapy may outweigh the benefits of continued opioid use. NIDA seeks studies for pharmacologic management with or without non-pharmacological approaches for managing chronic pain in those currently using long-term opioids. Interventions can target patients, health care providers (inclusive of pharmacists) or health care systems to reduce chronic pain and opioid-related risks and improve quality of life.

This funding opportunity announcement (FOA) is part of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative bolsters research across NIH to (1) improve treatment for opioid misuse and addiction and (2) enhance pain management. More information about the HEAL Initiative is available at: https://heal.nih.gov/

Announcement Number: RFA-DA-23-041

Closing Date: September 27, 2022

Description: Through the HEAL Initiative, NIH requests applications for studies designed to develop and test sustainable, scalable interventions to prevent opioid misuse, opioid use disorder, and co-occurring mental health conditions by intervening directly on social determinants of health (SDOH). This initiative aims to build an evidence base for preventive interventions that address inequities, social risks and/or social disadvantage. Interventions targeting social determinants may be structural (e.g. policy, regulatory, or systemic-wide changes) or designed to alter outcomes of individuals affected by contextual risk factors, and may be implemented in conjunction with psychosocial interventions designed to address behavioral risks.

Announcement Number: RFA-DA-23-051

Closing Date: February 2, 2023

Notice Number: NOT-OD-22-150

Related Announcements

NOT-OD-21-141 - Extramural Loan Repayment Program for Health Disparities Research (LRP-HDR)

NOT-OD-22-148 - Extramural Loan Repayment Program for Clinical Researchers (LRP-CR)

NOT-OD-22-149 - Extramural Loan Repayment Program for Pediatric Research (LRP-PR)

NOT-OD-22-151 - Extramural Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds (LRP-IDB)

NOT-OD-22-152 - Extramural Loan Repayment Program for Contraception and Infertility Research (LRP-CIR)

NOT-OD-22-153 - Extramural Loan Repayment Program for Research in Emerging Areas Critical to Human Health (LRP-REACH)

Purpose

This Notice replaces NOT-OD-21-141 and provides program-specific information for the Extramural Loan Repayment Program for Health Disparities Research (LRP-HDR). The NIH Loan Repayment Programs (LRPs) are a set of programs established by Congress and designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers.

Additional detailed information about each LRP is provided at https://www.lrp.nih.gov/eligibility-programs and www.lrp.nih.gov/apply.

The NIH invites qualified health professionals who contractually agree to engage in NIH mission-relevant research for an average of at least 20 hours each week for at least two years, initially, to apply for an award in the Extramural LRP. The Extramural LRP repays up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research at a domestic, nonprofit, or government entity. Research funding from NIH is not required to participate in the Extramural LRP. LRP awards are based on an applicant's potential to build and sustain a research career.

Extramural LRP applications will be accepted from September 1 until November 17, 2022.

Agency: Alzheimer's Drug Discovery Foundation

Description: The Alzheimer’s Drug Discovery Foundation is accepting applications for its core funding programs.

• Drug Development: The Drug Development RFP seeks to support in vivo preclinical studies that advance lead molecules developed for Alzheimer’s disease and related dementias to IND-enabling studies. The proposed studies should be structured to deliver a compound with strong potential for clinical and commercial application. This funding opportunity prioritizes novel drug mechanisms and modes of action related to the biology of aging and other emerging therapeutic areas for dementia.
•  Program to Accelerate Clinical Trials (PACT): The PACT RFP supports IND-enabling studies and early-phase clinical trials that test promising pharmacological interventions and devices for Alzheimer’s disease (AD) and related dementias. Both disease-modifying and symptomatic agents will be considered. This funding opportunity prioritizes diverse drug mechanisms and modes of action related to the biology of aging and other emerging therapeutic areas for dementia.
•  Neuroimaging and CSF Biomarker Development: The aim of this RFP is to further develop and validate established biomarkers for which there is a clear clinical need in Alzheimer's disease and related dementias. This RFP prioritizes biomarkers with a defined context of use, a clear advantage over other relevant biomarkers, and a path to commercialization and/or clinical use.
•  Prevention Pipeline: The ADDF seeks to support studies of cognitive symptoms due to health conditions, comparative effectiveness research, and epidemiological studies that probe whether the use or choice of drugs alters the risk for dementia or cognitive decline.

Letter of Intent – September 30, 2022

Invited Full Proposal – December 2, 2022 

Agency: U.S. Department of Justice (DOJ) – Office of Justice Programs (OJP) – Office of Juvenile Justice and Delinquency Prevention (OJJDP)

Description: Project sites are expected to use funding to implement violence prevention strategies targeted toward middle and high school age youth who have multiple risk factors for violence. Specific objectives include:

• Increase protective factors to prevent violence and delinquent behavior by youth.
• Contribute to sustained future reductions in youth violence, particularly gun and gang violence.

For this solicitation, applicants must develop and implement a youth violence prevention strategy targeting middle and high school age youth and/or those youth having multiple risk factors for violence. Applicants should discuss how they will implement the following deliverables in their application that will be delivered as a result of this program.

• Develop new or enhance existing direct service programs for youth with multiple risk factors for violence, including youth gang/group involvement and youth gang/group violence.
• If proposing a program enhancement, the applicant should include a description of the existing program and details on how funding will support program enhancements.
• Identify a specific referral system for how youth will be identified and referred to the program for services.

Funded sites should include strategies that support youth with in-home or community-based services that address the risk factors and support protective factors related to violence prevention.

Announcement Number: O-OJJDP-2022-171400

Closing Date: August 29, 2022

Related Announcements

OTA-22-006 - NIH All of Us Engagement, Communications, and Enrollment Partners Other Transactions (OT) Research Opportunity Announcement (ROA)

Issued by Office of The Director, National Institutes of Health (OD)

ROA Open Period: May 26, 2022 to May 23, 2025 (Note: open solicitation period includes multiple white paper deadlines within each calendar year)

Overview: The All of Us Research Program, within the Office of the Director (OD), has issued a research opportunity announcement (ROA) to solicit white papers supporting various Areas of Interest (AOIs). A ROA is a method of solicitation that announces the anticipated availability of Other Transactions (OT) awards, a special type of legal instrument other than contracts, grants, or cooperative agreements.

Purpose: The purpose of this announcement is to fund organizations who can help All of Us build its cohort of volunteers who reflect the rich diversity of the United States and are actively engaged as partners. These funded organizations will help design and implement strategies to raise awareness of the program through community and health care provider organizations, drive increased enrollment of participants, foster regular communication with participants, and engage the research community to use the data being gathered.

Pre-Submission Webinar: A webinar will be conducted for potential offerors. The purpose of the webinar will be to provide potential offerors with a better understanding of the scope of the All of Us Research Program and objectives of this ROA. The date and time of the webinar will be made available via the SAM.gov link below.

White Paper Deadlines: This ROA will remain open for three (3) years from its issue date, unless otherwise updated via an amendment on SAM.gov, and includes multiple white paper (WP) submission deadlines. All WP deadline times are 3:00 PM Eastern Time. The first white paper deadline is August 31, 2022. Additional deadlines, are listed in the full opportunity announcement on SAM.gov.

Documents and Related Links: The full ROA package can be accessed via the following link: https://sam.gov/opp/69da7ceff0e4456b9fad4b15f074d4de/view. Potential offerors are encouraged to carefully review the announcement in its entirety before submitting questions and/or preparing a white paper submission.

Purpose: The National Institute of General Medical Sciences announces the Institutional Research and Academic Career Development Award (IRACDA) Program, which provides support for a mentored postdoctoral research experience at a research-intensive institution combined with an opportunity to develop critical teaching and mentoring skills at a teaching-intensive partner institution with a diverse student population. Accordingly, the IRACDA program requires effective partnerships between a research-intensive institution and a teaching-intensive partner institution that has a historical mission or a demonstrated commitment to educating students from groups underrepresented in the biomedical research workforce.

The primary goal of the IRACDA program is to develop a diverse pool of well-trained biomedical scientists who have the necessary knowledge and skills to pursue independent academic teaching and research careers. Proposed programs should include, but are not limited to, the ability to:

• Implement current evidence-informed teaching, mentoring, and research training methods;
• Teach rigorous and safe scientific research methodologies and findings to individuals from diverse backgrounds;
• Work well in teams with colleagues from a variety of cultural and scientific backgrounds;
• Mentor students with sensitivity to cultural differences; and
• Create inclusive, safe, and supportive teaching and learning environments.

Note: NIGMS encourages multiple PDs/PIs, particularly when each brings a unique perspective and skill set that will enhance the career development program. At least one of the PDs/PIs should be an established investigator in the biomedical sciences and capable of providing both administrative and scientific leadership needed for the development and implementation of the proposed program. Additional PD(s)/PI(s), including individuals from the teaching-intensive institution, with experience in the science of education, relevant social science disciplines, program evaluation, mentoring, and university administration may be included to achieve the program goals. 

Funding Amount/ Project Period: Up to 5 years

Institutional Limit: 1

Internal Competition: To participate in the university’s selection process, please upload the following, assembled into a single PDF file, to the Office of the Vice President for Research via this portal with a copy to your Associate Dean for Research by August 16, 2022:

1. Names and departments or affiliations of the Project Director and other key personnel or partners;
2. Title of program and/or funding opportunity announcement number;
3. Brief project description (2 pages maximum)
4. Brief biographical sketch

A committee will be convened to review the material and make a recommendation. For questions or issues with submission through the portal, email the limited submission mailbox ([email protected]), or call 257-2861.

Agency Deadline: October 3, 2022

Purpose: This Notice is a reissue of and supersedes NOT-MD-19-001 - Notice of Special Interest in Research on the Health of Sexual and Gender Minority (SGM) Populations which calls for research on the health of sexual and gender minority populations. SGM populations include, but are not limited to, individuals who identify as lesbian, gay, bisexual, asexual, transgender, Two-Spirit, queer, and/or intersex. Individuals with same-sex or -gender attractions or behaviors and those with a difference in sex development are also included. These populations also encompass those who do not self-identify with one of these terms but whose sexual orientation, gender identity or expression, or reproductive development is characterized by non-binary constructs of sexual orientation, gender, and/or sex.

Purpose: The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICs) are issuing this Notice of Special Interest (NOSI) to encourage applications proposing to test multilevel strategies and interventions to improve the uptake of evidence-based screening services across the lifespan and in populations including, but not limited to, those experiencing health disparities and those that are underserved. Studies addressing efficacy, effectiveness, dissemination and implementation research, as well as studies seeking to understand and address barriers to screening are encouraged. The specific research interests of participating NIH ICs are detailed within.

Investigators planning to submit an application in response to this NOSI are strongly encouraged to contact and discuss their proposed research/aims with Program staff/Scientific Contacts listed on this NOSI well in advance of the application receipt date to better determine appropriateness and interest of the relevant Institute.

Purpose: The University of Kentucky Women and Philanthropy Network is accepting applications for its grants program. In 2007, a group of women came together with a common vision – to build a better UK and Commonwealth. Each year membership contributions are pooled to support the University, its students, research and programs by awarding funds through grants.

Colleges and programs are asked to coordinate proposal requests with the dean of their college or appropriate vice president to whom the program reports. The top 10 proposals will be offered the opportunity to present to the Leadership Council of Women and Philanthropy November 3, 2022. Funding will be available in January 2023 to be used by August 1, 2024.

Eligibility: University faculty and students are eligible. Students must be enrolled at UK and be in good standing. Eligible students include undergraduate, graduate and professional degree students. Transfer and non-traditional students via traditional and alternative paths are eligible.

Funding Amount/ Project Period: up to $50,000 for 1 year

Institutional Limit:  2 per college or program

Internal Competition: Internal coordination will be handled at the college or vice president level. Individuals interested in this program should contact their associate dean for research or the office of the responsible vice president for research as soon as possible.

For questions, email [email protected].

Agency Deadline: July 31, 2022