Fall 2022

RiverVest Builds Strong Portfolios

Despite ongoing macroeconomic and geopolitical uncertainties, RiverVest remains bullish on life science investment opportunties.


In recent months, we saw robust activity across our portfolios:


    Two successful exits (see story below)

    Eight portfolio companies raised additional capital

    Nine portfolio companies achieved clinical or development milestones


We attribute our success to focusing on early-stage companies that address a significant unmet need, managing key risks, and ensuring capital efficiency throughout the investment cycle.


Additionally, we take steps to ensure that our reserves are allocated appropriately so that we are best positioned to support our portfolio companies and to capitalize on investment opportunities created by dynamic market conditions.

Good Therapeutics and Standard Bariatrics Acquired

Two portfolio companies in RiverVest Venture Fund IV entered definitive acquisition agreements in the third quarter, coincidentally closing on the same day – September 27, 2022.


Biopharma company Good Therapeutics was acquired by Roche (SIX: RO, ROG; OTCQX: RHHBY) for $250 million up front, with the potential for additional payments based on the achievement of predetermined milestones. 


Medical device company Standard Bariatrics was acquired by Teleflex Incorporated (NYSE: TFX) for $170 million up front, with up to $130 million in potential milestone payments.


These exits demonstrate RiverVest’s investment strategy in practice.


     We understood the significant unmet medical needs they address

     We believed in the strength of their management teams

     We invested early and participated actively on their boards to effectively manage risk and maximize returns 


The Details

RiverVest co-led Good’s $22 million Series A Preferred Equity round in 2018 and co-led its $26.4 million Series B round in 2021.


RiverVest led Standard Bariatrics’ $20 million Series A financing in 2018 and participated in its $35 million Series B round in 2021. 

 

In addition to investment capital, RiverVest provided scientific, operational, financial, and investment guidance.


     Director John McKearn, Ph.D. served on the board at Good.

     VP Karen Spilizewski served on the board at Standard Bariatrics and Managing Director Jay Schmelter acted as a board observer.

Portfolio News

For the latest news, be sure to visit the RiverVest website and follow us on LinkedIn.


Recent announcements include:

Positive Topline Data Announced from Mirum’s LIVMARLI Phase 3 MARCH Study in Progressive Familial Intrahepatic Cholestasis (PFIC) – 10/24/2022

Avalyn Pharma Appoints Lyn Baranowski Chief Executive Officer – 10/17/2022

Allakos raises $150 million through a secondary equity offering 

Good Therapeutics Announces Acquisition of Conditionally Active PD-1-regulated IL-2 Program by Roche – 9/7/2022

Teleflex to Expand Its Surgical Portfolio with Differentiated Stapling Technology for Bariatric Surgery – Signs Definitive Agreement to Acquire Standard Bariatrics – 8/22/2022

Bluejay Therapeutics raises $41 million in Series B round to drive clinical trials in chronic hepatitis. – 8/16/2022

Allakos Provides Business Update and Reports Second Quarter 2022 Financial Results – 8/4/2022

Reneo Pharmaceuticals Reports Positive Results from REN001 Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Study and Provides Additional Development Updates – 7/27/2022

Wugen Receives U.S. FDA Fast Track and Rare Pediatric Disease Designations for WU-CART-007 for the Treatment of R/RT-ALL/LBL 7/19/2022

Case Study: Mirum Pharmaceuticals

Visit the Case Studies page on our website to hear what Mirum CEO Chris Peetz, pediatric hepatologist Dr. Binita Kamath, and RiverVest Managing Director Niall O’Donnell have to say about the remarkable therapies Mirum is developing to fight rare liver disease. 

Jay Schmelter on NVCA Webinar Spotlighting St. Louis

The National Venture Capital Association (NVCA) hosted a live webinar on Aug. 31, 2022 spotlighting the innovation ecosystem in St. Louis. Missouri Representative Ann Wagner introduced the panel:


Jay Schmelter, RiverVest Venture Partners

Dedric Carter, Washington University in St. Louis

Jason Hall, Greater St. Louis, Inc. 

Elise Miller Hoffman, Cultivation Capital 

Brian Hopcraft, Lewis & Clark Ventures 

Judy Sindecuse, Capital Innovators


RiverVest is proud to be headquartered in St. Louis at the intersection of a major medical research university and a growing innovation ecosystem. We are strategically positioned to find, cultivate, and harvest opportunities where others may not have focused.

STAY CONNECTED
Twitter  Linkedin  

RiverVest Venture Partners is a leading life science venture capital firm focused on improving the lives of patients, supporting entrepreneurs, and earning the trust of investors through science, strategy, and innovation. 

Visit our website