February 2026


Issue No. 24

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CORNERSTONE HAPPENINGS

Cornerstone’s Chief Medical Officer, Dr. Edith A. Perez delivered the keynote presentation “Every Step Counts: How Far We’ve Come—and Where We’re Going” at the Donna Foundation (The DONNA Foundation | Support for Breast Cancer Patients) Thrive Well program in collaboration with the Mayo Clinic on January 31st 2026. Her talk highlighted advances in cancer care, with a focus on future tools and innovation and the importance of collaboration of everyone involved in the health care ecosystem, drawing on decades of clinical and research experience. Over 10,000 people braved the cold and participated in the DONNA Marathon Weekend 2026 event held in Jacksonville Florida! 

DONNA Marathon Weekend 2026 - The DONNA Foundation 

Our SABCS Data Review was held virtually on January 22nd 2026, with our cochairs Dr. Edith Perez, Dr. Sujith Kalmadi, and Dr. Eric Schaefer highlighting key clinical trials presented at the 2025 San Antonio Breast Cancer Symposium held in early December providing a comprehensive review with discussion featuring interactive polling and live chat Q&A. We thank the more than 100 attendees who joined us for the evening! Click here to access the slides and download the key takeaways.

We are looking forward to our ASH Data Review to be held virtually on February 19th 2026 co-chaired by Dr. Pankit Vachhani (Assistant Professor of Medicine at the University of Alabama at Brimingham) with Dr. Sujith Kalmadi (Ironwood Cancer & Research Centers) and Dr. Eric S. Schaefer (Highlands Oncology Group) who will highlight the important data that was presented at the 67th ASH Annual Meeting and Exposition in December with a focus on leukemia, myeloma and lymphoma.

 
 

CLINICAL INVESTIGATION

We are pleased to share that our efforts toward advancing real-world oncology research continue to progress. As of February 6th, 2026 enrollment in our initial clinical investigation study, Prospective Observational Study on Infusion-Related Reactions with Docivyx® or Docetaxel in Participants with Solid Malignancies [Protocol CSNAVX1] sponsored by Avyxa has reached 98 patients across all 6 participating practices. Almost there - keep up the good work!

  • Northwest Cancer Centers – 25 patients
  • Cancer Center of Kansas – 22 patients 
  • Ironwood – 19 patients 
  • Highlands Oncology Group – 13 patients 
  • Zangmeister – 10 patients 
  • Astera – 9 patients 

Our second clinical investigation study Retrospective Observational Study on HR+ and HER2-Low (IHC 1+ or 2+ with ISH negative) and HER2-Ultralow (IHC 0 with membrane staining) Metastatic Breast Cancer [Protocol CSNDSI01] sponsored by DSI is well underway with 11 active sites and 191 patients enrolled!

  • Cancer Center of Kansas – 33 patients
  • Singing River – 30 patients
  • HealthPartners – 30 patients
  • Toledo – 26 patients
  • Northwest Cancer Center – 26 patients
  • Premier Hematology and Oncology – 17 patients
  • Renown Health — 10 patients
  • Zangmeister – 8 patients
  • Profound Research LLC – 6 patients
  • Cancer Care Associates of York - 5 patients
  • Maryland Oncology — currently screening for eligible patients


As a quick reminder, this study is a retrospective study chart review and has been deemed to be IRB exempt by the Central IRB. Thanks to all who have already committed to this initiative, we look forward to filling out the remaining few open research site slots! 


We are excited to share that we are working towards activating sites for our third Clinical Investigation study - DSI02: EGFRm NSCLC Dato- DXd sponsored by DSI. We look forward to engaging with initial sites and welcome additional participation! 


If interested in participating in any of our clinical trials, please contact Rachel M. Condjella, Ph.D. — Senior Director of Clinical Investigations & Market Insights rcondjella@cornerstoneonc.com or Josh Ondatje – Director of Clinical Operations jondatje@cornerstoneonc.com and Lizette Clark — Director of Clinical Operations lclark@cornerstoneonc.com for more information.

Your News, Our Newsletter!

We want to hear from you! Share your exciting projects, upcoming events, or personal milestones with the Cornerstone Specialty Network community.

2026 UPCOMING EVENTS

Cornerstone Specialty Network's Strategic Advisor National Summit will be held in Scottsdale, AZ in March 2026. Registration is now closed.

Our Lung Data Review to be held virtually on May 7th 2026 with Dr. Mekhail, Dr. Schaefer and Dr. Kalmadi. Click below to join the waitlist.

CLINICAL UPDATES

FDA Updates for January 2026

Oncology (Cancer)/Hematologic Malignancies Approval Notifications | FDA 


On January 27, 2026, the Food and Drug Administration approved daratumumab and hyaluronidase-fihj (Darzalex Faspro, Janssen Biotech, Inc.) in combination with bortezomib, lenalidomide, and dexamethasone (VRd) for adults with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplant (ASCT) evaluated in CEPHEUS trial. Read More


Thank You

Cornerstone would like to take this opportunity to thank our select pharma partners for their support of our programs enabling us to provide unique opportunities to connect with our network, deliver key educational programs, and ultimately benefit patient care. 

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