Editor's Note
Six new monoterpenoid  glycosides and three known compounds were isolated from the 70%-EtOH extract of  Schisandra chinensis  rattan stems. The structures of the new compounds were elucidated by detailed spectroscopic analyses. The neuroprotective activities of compounds 1–9 were evaluated on the two co-culture models of microglia and neurons cells and astrocytoma and neurons cells.
Abstract

Six new monoterpenoid  glycosides , including thymoquinol 5-O-α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside (1), cuminic acid 7-O-α-D-arabinofuranosyl-(1 → 6)-β-d-glucopyranosyl ester (2), p-cymene 7-O-α-D-arabinofuranosyl-(1 → 6)-β-D-glucopyranoside (3), p-methylhyd- ratropic acid 9-O-α-D-arabinofuranosyl-(1 → 6)-β-d-glucopyranosyl ester (4), (R)-p-cymene 9-O-α- D-arabinofuranosyl-(1 → 6)-β-D-glucopyranoside (5), and (R)-p-cymene 9-O-β-D-apiofuranosyl-(1 → 6)-β-D-glucopyranoside (6), together with three known compounds, such as (R)-p-cymene 9-O-β-D-glucopyranoside (7), thymoquinol 5-O-β-D-glucopyranoside (8), and thymoquinol 2-O-β-D-glucopyranoside (9) were isolated from the 70%-EtOH extract of  Schisandra chinensis  rattan stems. The structures of the new compounds were elucidated by detailed spectroscopic analyses. Meanwhile, the neuroprotective activities of compounds 1–9 were evaluated on the two co-culture models of microglia and neurons cells and astrocytoma and neurons cells.

2019 Annual Fund Sponsors: