September 2018
Registry Trial Results Presented at ESC

Dr. Raymond Kwong from the Harvard Medical School in Boston presented his findings on how multi-center stress cardiovascular magnetic resonance studies have shown excellent values in management of patients with suspected ischemia at the recent  European Society of Cardiology (ESC) Congress  in   Munich, Germany.

The objectives of the SPINS  study were to:
  • Evaluate the prognostic value of stress CMR in patients presenting with CP syndromes, in a real-world multicenter setting in the U.S.; and
  • As a preliminary analysis, to assess the utilization and costs of cardiac tests, after performance of the index stress CMR study.
"The SPINS cohort is a retrospective observation study from 13 U.S. cardiac MRI centers (9 AMC, 4 private practice) consisting of N=2,371 patients who underwent stress CMR scanning between Jan. 1, 2008 through Dec. 31, 2013, for evaluation of clinical signs and symptoms suspicious of cardiac ischemia," said Kwong, lead investigator of the study. "Patients overall had a 33 percent pretest likelihood of CAD [coronary artery disease] by CAD consortium scores, and 32 percent were found to have ischemia or myocardial infarction. All patients were aimed to have clinical follow-up of at least four years.

"Stress CMR is an effective modality in the real-world setting in detecting patients at high risk of cardiac events," said Kwong. "In addition, preliminary costs analyses suggest its use may potentially reduce costs of downstream cardiac testing. Our evidence supports the expanded utilization of stress CMR in evaluation of chest pain syndromes in the United States."  

New Paper Published by the SCMR Clinical Trials Committee 

The Clinical Trials Committee has published a new paper in the  Journal of Cardiovascular Magnetic Resonance titled "SCMR expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification".  The objective of the Clinical Trial Task force was to summarizes the evidence to emphasize where currently CMR-guided clinical care can indeed translate into meaningful use and efficient deployment of resources results in meaningful and efficient use. The objective of the present initiative was to provide an appraisal of evidence on analytical validation, including the accuracy and precision, and clinical qualification of parameters in disease context, clarifying the strengths and weaknesses of the state of art, as well as the gaps in the current evidence. This paper is complementary to the existing position papers on standardized acquisition and post-processing ensuring robustness and transferability for widespread use.

SCMR Launches New Corporate Advisory Board

The SCMR recognizes the need to effectively incorporate industry partner input into the activities directed towards achieving the mission of the Society; and therefore has initiated the formation of a Corporate Advisory Board (CAB). The CAB will be comprised of a coalition of global industry leaders together with clinical, academic, and scientific leaders in the field of CMR.  The focus of the CAB will be on the creation of soundly developed, actionable projects. These projects will have the overarching goal of increasing the appropriate utilization of CMR with the expected result of raising the standard and availability of cardiovascular healthcare, globally.

The founding members of the Corporate Advisory Board include:
  • Arterys
  • Circle Cardiovascular Imaging
  • Cohesic
  • GE Healthcare
  • Guerbet
  • Heart Imaging Technologies
  • Medis Medical Imaging Systems 
  • Myocardial Solutions
  • NeoSoft
  • Philips
  • Siemens Healthineers
Thank you to all the founding members to help advance the field of CMR.
Case of the Week  

A 6-year old boy with Kabuki syndrome and previously diagnosed bicuspid aortic valve was referred for elective cardiology follow-up after his family relocated to a new state.  His past medical history was remarkable for developmental delay, bilateral sensorineural hearing loss, visual deficits (strabismus with esotropia, right hypertropia and latent bilateral nystagmus), ureteropelvic obstruction and moderate-severely pronated valgus flat feet.

JCMR Articles

Research: Cardiovascular magnetic resonance imaging in the prospective, population-based, Hamburg City Health
cohort study: objectives and design
Sebastian Bohnen, et al.
Published on: 24 September 2018

Research:  Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
Wenjia Bai, et al.
Published on: 14 September 2018

Research:   Comparison of left ventricular strains and torsion derived from feature tracking and DENSE CMR
Gregory J. Wehner, et al.
Published on: 13 September 2018

Research:   Blood volume measurement using cardiovascular magnetic resonance and ferumoxytol: preclinical validation
Rajiv Ramasawmy, et al.
Published on: 10 September 2018