Study finds promising therapeutic target for colitis
An international research group, led by Jamey Marth, Ph.D., has shown that the neuraminidase 3 enzyme is responsible for the onset and progression of colitis—a chronic digestive disease caused by inflammation of the colon. The study findings, recently published in PNAS, represent a scientific advance toward a targeted therapy to help the millions of people worldwide affected by the disorder. Recurrent infections of Salmonella, a common food poisoning pathogen, can lead to colitis.