May 2021
The Science Spotlight newsletter previously featured publications from Brigham researchers in high-impact journals collated by Harvard Paper Chase. This list has since been discontinued. Beginning in February 2021, papers from journals with the highest impact factors will be highlighted. Recognizing that journal impact factor is not an absolute way to feature all scientific publications of significant merit, we welcome investigators to submit noteworthy articles to be featured in the newsletter through this REDCap survey.
*The gold colored buttons denote COVID-19 related publications.
In April there were:
1,108 total papers listed in PubMed with Brigham authors
49 tweets about new research and 98.8K tweet impressions
65 awards with $47,733,536 in new grants
A Reminder from the Office of Strategic Communication: If you have research news to share, please contact us. Ideally, we work with researchers as soon as a paper is accepted at a journal to develop an appropriate communication strategy in advance of publication. For media relations and social media support, email mediarelations@bwh.harvard.edu or contact Haley Bridger directly at hbridger@bwh.harvard.edu
Gohil SH, Iorgulescu JB, Braun DA, Keskin DB, Livak KJ.
Nat Rev Clin Oncol. 2021 Apr;18(4):244-256. doi: 10.1038/s41571-020-00449-x. Epub 2020 Dec 4.
PMID: 33277626 Review.
Akimoto N, Ugai T, Zhong R, Hamada T, Fujiyoshi K, [et al.] Ogino S.
Nat Rev Clin Oncol. 2021 Apr;18(4):230-243. doi: 10.1038/s41571-020-00445-1. Epub 2020 Nov 20.
PMID: 33219329 Review.
Blass E, Ott PA.
Nat Rev Clin Oncol. 2021 Apr;18(4):215-229. doi: 10.1038/s41571-020-00460-2. Epub 2021 Jan 20.
PMID: 33473220 Free PMC article. Review.
Emile JF, Cohen-Aubart F, Collin M, Fraitag S, Idbaih A, [et al.] Haroche J.
Lancet. 2021 Apr 23:S0140-6736(21)00311-1. doi: 10.1016/S0140-6736(21)00311-1. Online ahead of print. PMID: 33901419 Review.
Lockman S, Brummel SS, Ziemba L, Stranix-Chibanda L, McCarthy K, [et al.] Currier J; IMPAACT 2010/VESTED Study Team and Investigators.
Lancet. 2021 Apr 3;397(10281):1276-1292. doi: 10.1016/S0140-6736(21)00314-7.
PMID: 33812487 Clinical Trial.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, [et al.] Zhou J; SCGE Consortium.
Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. PMID: 33828315 Free PMC article. Review.
Libby P.
Nature. 2021 Apr;592(7855):524-533. doi: 10.1038/s41586-021-03392-8. Epub 2021 Apr 21. PMID: 33883728 Review.
Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, [et al.] Wan EY.
Nat Med. 2021 Apr;27(4):601-615. doi: 10.1038/s41591-021-01283-z. Epub 2021 Mar 22. PMID: 33753937 Review.
Friedman GK, Johnston JM, Bag AK, Bernstock JD, Li R, [et al.] Gillespie GY.
N Engl J Med. 2021 Apr 29;384(17):1613-1622. doi: 10.1056/NEJMoa2024947. Epub 2021 Apr 10. PMID: 33838625
Kirtane AR, Verma M, Karandikar P, Furin J, Langer R, Traverso G.
Nat Nanotechnol. 2021 Apr;16(4):369-384. doi: 10.1038/s41565-021-00866-8. Epub 2021 Mar 22. PMID: 33753915 Review.
Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, [et al.] Quintana FJ.
Science. 2021 Apr 23;372(6540):eabf1230. doi: 10.1126/science.abf1230. PMID: 33888612
Humbert M, McLaughlin V, Gibbs JSR, Gomberg-Maitland M, Hoeper MM, [et al.] Badesch DB; PULSAR Trial Investigators.
N Engl J Med. 2021 Apr 1;384(13):1204-1215. doi: 10.1056/NEJMoa2024277.
PMID: 33789009 Clinical Trial.
McInnes IB, Anderson JK, Magrey M, Merola JF, Liu Y, [et al.] Behrens F.
N Engl J Med. 2021 Apr 1;384(13):1227-1239. doi: 10.1056/NEJMoa2022516. PMID: 33789011 Clinical Trial.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, [et al.] Ruan J, Wu H.
Nature. 2021 Apr 21. doi: 10.1038/s41586-021-03478-3. Online ahead of print. PMID: 33883744 
INSPIRATION Investigators, Sadeghipour P, Talasaz AH, Rashidi F, Sharif-Kashani B, [et al.] Bikdeli B.
JAMA. 2021 Apr 27;325(16):1620-1630. doi: 10.1001/jama.2021.4152. PMID: 33734299 Clinical Trial.
Schneider JL, Rowe JH, Garcia-de-Alba C, Kim CF, Sharpe AH, Haigis MC.
Cell. 2021 Apr 15;184(8):1990-2019. doi: 10.1016/j.cell.2021.03.005. Epub 2021 Apr 2. PMID: 33811810 Review.
Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, [et al.] Regev A.
Nature. 2021 Apr 29. doi: 10.1038/s41586-021-03570-8. Online ahead of print.
PMID: 33915569
Wilkinson JE, Franzosa EA, Everett C, Li C; HCMPH researchers and trainees; [et al.] Huttenhower C.
Nat Med. 2021 May;27(5):766-774. doi: 10.1038/s41591-021-01258-0. Epub 2021 Apr 5. PMID: 33820996 Review. 
Scheid JF, Barnes CO, Eraslan B, Hudak A, Keeffe JR, [et al.] Xavier RJ.
Cell. 2021 Apr 24:S0092-8674(21)00535-3. doi: 10.1016/j.cell.2021.04.032. Online ahead of print. PMID: 34015271 Free PMC article.
Davidson S, Coles M, Thomas T, Kollias G, Ludewig B, [et al.] Buckley CD.
Nat Rev Immunol. 2021 Apr 28. doi: 10.1038/s41577-021-00540-z. Online ahead of print.
PMID: 33911232 Review.
Gaziano L, Giambartolomei C, Pereira AC, Gaulton A, Posner DC, [et al.] Casas JP; VA Million Veteran Program COVID-19 Science Initiative.
Nat Med. 2021 Apr;27(4):668-676. doi: 10.1038/s41591-021-01310-z. Epub 2021 Apr 9. PMID: 33837377
Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, [et al.] Tall AR.
Nature. 2021 Apr;592(7853):296-301. doi: 10.1038/s41586-021-03341-5. Epub 2021 Mar 17.
PMID: 33731931
Lee TH.
N Engl J Med. 2021 Apr 29;384(17):1586-1587. doi: 10.1056/NEJMp2035869. Epub 2021 Apr 24. PMID: 33914438 No abstract available.
Meyerhardt JA, Shi Q, Fuchs CS, Meyer J, Niedzwiecki D, [et al.] Shields AF.
JAMA. 2021 Apr 6;325(13):1277-1286. doi: 10.1001/jama.2021.2454. PMID: 33821899 Clinical Trial.
Khan MS, Ali SAM, Adelaine A, Karan A.
Lancet. 2021 May 22;397(10288):1863-1865. doi: 10.1016/S0140-6736(21)00938-7. Epub 2021 Apr 21. PMID: 33894143 Free PMC article. No abstract available.
Alvarez-Arango S, Ogunwole SM, Sequist TD, Burk CM, Blumenthal KG.
N Engl J Med. 2021 Apr 8;384(14):1283-1286. doi: 10.1056/NEJMp2031891. Epub 2021 Apr 3. PMID: 33830710 No abstract available.
Chhabra KR, Fuse Brown E, Ryan AM.
N Engl J Med. 2021 Apr 15;384(15):1381-1383. doi: 10.1056/NEJMp2035905. Epub 2021 Mar 17. PMID: 33730453 No abstract available.
Ota M, Nagafuchi Y, Hatano H, Ishigaki K, Terao C, [et al.] Fujio K.
Cell. 2021 Apr 21:S0092-8674(21)00429-3. doi: 10.1016/j.cell.2021.03.056. Online ahead of print.
PMID: 33930287
Gowda V, Beall RF, Kesselheim AS, Sarpatwari A.
Nat Biotechnol. 2021 Apr;39(4):414-417. doi: 10.1038/s41587-021-00877-9.
PMID: 33846649 No abstract available.
Barsky BA, Reinhart E, Farmer P, Keshavjee S.
N Engl J Med. 2021 Apr 29;384(17):1583-1585. doi: 10.1056/NEJMp2100609. Epub 2021 Mar 3. PMID: 33657290 No abstract available.
Luyckx VA, Harris DCH, Varghese C, Jha V.
Lancet. 2021 Apr 15:S0140-6736(21)00732-7. doi: 10.1016/S0140-6736(21)00732-7. Online ahead of print. PMID: 33865498 No abstract available.
Shi DD, Mamon HJ.
J Clin Oncol. 2021 Apr 1;39(10):1186-1188. doi: 10.1200/JCO.20.03666. Epub 2021 Feb 9. PMID: 33560869 No abstract available.
Blumenthal KG, Robinson LB, Camargo CA Jr, Shenoy ES, Banerji A, Landman AB, Wickner P.
JAMA. 2021 Apr 20;325(15):1562-1565. doi: 10.1001/jama.2021.3976.
PMID: 33683290
Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, [et al.] Balazs AB.
Cell. 2021 Apr 29;184(9):2372-2383.e9. doi: 10.1016/j.cell.2021.03.013. Epub 2021 Mar 12.
PMID: 33743213 Free PMC article. 
Blumenthal KG, Freeman EE, Saff RR, Robinson LB, Wolfson AR, [et al.] Shenoy ES.
N Engl J Med. 2021 Apr 1;384(13):1273-1277. doi: 10.1056/NEJMc2102131. Epub 2021 Mar 3. PMID: 33657292 Free PMC article. No abstract available.
Mina MJ, Peto TE, García-Fiñana M, Semple MG, Buchan IE.
Lancet. 2021 Apr 17;397(10283):1425-1427. doi: 10.1016/S0140-6736(21)00425-6. Epub 2021 Feb 17. PMID: 33609444 Free PMC article. No abstract available.
Katz IT, Weintraub R, Bekker LG, Brandt AM.
N Engl J Med. 2021 Apr 8;384(14):1281-1283. doi: 10.1056/NEJMp2103614. Epub 2021 Apr 3. PMID: 33830709.
Adamson AS, Mazer BL, Welch HG.
N Engl J Med. 2021 Apr 8;384(14):e54. doi: 10.1056/NEJMc2101980.
PMID: 33826836 No abstract available.
Olshansky B, Bhatt DL, Chung MK.
JAMA. 2021 Apr 6;325(13):1332-1333. doi: 10.1001/jama.2021.0824.
PMID: 33821905 No abstract available.
Other Featured Publications
Garo LP, Ajay AK, Fujiwara M, Gabriely G, Raheja R, [et al.] Murugaiyan G.
Nat Commun. 2021 Apr 23;12(1):2419. doi: 10.1038/s41467-021-22641-y. PMID: 33893298; PMCID: PMC8065171.
Weaver MD, Sletten TL, Foster RG, Gozal D, Klerman EB, [et al.] Czeisler CA.
Sleep Health. 2021 Mar 29:S2352-7218(21)00030-9. doi: 10.1016/j.sleh.2021.02.009. Epub ahead of print. PMID: 33795195.
Lu MY, Williamson DFK, Chen TY, Chen RJ, Barbieri M, Mahmood F.
Nat Biomed Eng. 2021 Mar 1. doi: 10.1038/s41551-020-00682-w. Epub ahead of print. PMID: 33649564.
Lee JTH, Patikas N, Kiselev VY, Hemberg M.
Nat Methods. 2021 Mar;18(3):262-271. doi: 10.1038/s41592-021-01076-9. Epub 2021 Mar 1. PMID: 33649586; PMCID: PMC7116898.
Watson KL, King LP
Obstet Gynecol. 2021 Apr 1;137(4):657-661. doi: 10.1097/AOG.0000000000004309. PMID: 33706362.
Shah PP, Diaz AA.
ATS Sch. 2020 Dec 7;2(1):9-12. doi: 10.34197/ats-scholar.2020-0131CM. PMID: 33870318; PMCID: PMC8043278.
Rotenstein L, Lamey J, Wichmann L, Arbour M, Lakin J, Cunningham R.
NEJM Catalyst. 2021 Mar. doi:10.1056/cat.20.0600. 
El Fekih R, Hurley J, Tadigotla V, Alghamdi A, Srivastava A, [et al.] Azzi JR.
J Am Soc Nephrol. 2021 Mar 3;32(4):994–1004. doi: 10.1681/ASN.2020060850. Epub ahead of print. PMID: 33658284; PMCID: PMC8017553.
Submit Your Publication to Science Spotlight
We recognize there are many other Brigham publications in Journals that may not be included on this list, so we would like to extend the opportunity to our research community. If you and/or your Brigham colleagues are the first and/or last author on a recent publication, we want to include you in our Science Spotlight newsletter! Please fill out this brief REDCap form with the details of your publication.
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