Siglec Receptors Unveil New Avenues for Immunity Therapy Research

Siglecs – Immunomodualtory recepter protein

Siglecs are a class of immunomodulatory sialic acid-binding receptor proteins that bind to glycans containing sialic acid (Sia). Studies have shown that abnormal sialic acid to Siglec interactions are related to a variety of diseases. As such, these interactions are a priority target that can have major influences on pathogenesis.

Siglecs in human and mouse

Siglecs mainly exist on the surface of immune cells and participate in a variety of immune activities, including regulating inflammatory responses, leukocyte proliferation, host-microbe interactions, and cancer immunity. They play an important regulatory role in innate immunity and adaptive immunity. Explore our high-quality

Siglec Recombinant Proteins covering 11 subtype molecules, Siglec-2 Target-couple beads, Siglec-3 Target-couple beads products!