Special Report: Health System Leaders Developing the Frameworks to Let AI Flourish



Health systems are moving beyond AI pilots to an operating model centered on measurable outcomes, fit-for-purpose governance, and disciplined change management. In this special report, healthsystemCIO Editor-in-Chief Anthony Guerra spoke with leaders from UCI Health, Duke, Mercy, Mayo Clinic Platform, John Muir Health, Cedars-Sinai, and Mount Sinai who described single-front-door intake, risk tiering, time-boxed pilots, and human-in-the-loop oversight. Early value concentrates in administrative work and call-center automation, while clinical uses advance carefully. Data quality, workforce activation, and swap-ready architectures enable sustained enterprise scale.

Experts Behind the Report -