Michael “Collins” Scott, MD, presented at the ACS - Committee on Trauma 100th Anniversary Meeting in Seattle, WA for the Resident Paper Competition in the Basic Science Division. He was the winner of the Region VI competition.

His presentation was titled: “The effect of dexmedetomidine on microglia cytokine expression and metabolic enzyme activity.” Coauthors include Scott D. Olson, PhD; Charles S. Cox, Jr., MD.

The paper discussed one of their in vitro studies of microglia, an important immune cell in neuroinflammation. After treating with different inflammatory stimuli, Scott and his team observed changes in the expression of inflammatory cytokines and glycolytic enzyme activity in microglia to better characterize their inflammatory profile. They also studied how dexmedetomidine, a commonly used critical care sedative, affected the inflammatory profile of microglia.