Dr. Samuel Waxman received the"Friendship Award"
Samuel Waxman, MD, Distinguished Service Professor, Icahn School of Medicine at Mount Sinai, and founder and CEO of the Samuel Waxman Cancer Research Foundation, received the "Friendship Award" from the People's Republic of China in recognition of more than 30 years of U.S.-China scientific cooperation for cancer research and the successful development of a treatment for acute promyelocytic leukemia that now has a greater than 90% cure rate. The Vice-Premier of the People’s Republic of China, Liu He, presented the “Friendship Award,” to Dr. Waxman at a ceremony in Beijing in late September. 
2018 Accelerator Award
Mount Sinai’s Multiple Myeloma Program , Sundar Jagannath, MBBS , Director, is the recipient of the 2018 Multiple Myeloma Research Consortium (MMRC) Accelerator Award from the Multiple Myeloma Research Foundation (MMRF) in recognition of outstanding efforts and exceptional contributions to the rapid initiation and completion of clinical trials supported through the MMRC as well as leadership in the consortium. Mount Sinai has enrolled the largest number of patients on MMRC studies this year (more than 20% of total) and has brought to the Consortium innovative clinical translational efforts in the area of immune biology and myeloma genomic data analysis and validation. The award was presented by the MMRF at the 60 th annual meeting of the American Society of Hematology. Last year the Multiple Myeloma Program received the MMRC Innovator Award.
Dr. Ramon Parsons Honored by the Katie Oppo Research Fund
Ramon Parsons, MD, PhD, Director, The Tisch Cancer Institute, and Director, Mount Sinai Cancer, was honored on November 16 by the Katie Oppo Research Fund, dedicated to increasing awarenss and funding research that investigates the causes of ovarian cancer and avenues of prevention, treatment, and cure.
The Tisch Cancer Institute Developmental Funds Awards, 2018
Sixteen applications for The Tisch Cancer Institute Development Funds Awards, funded by the NCI Cancer Center Support Grant, were considered this year by the Review Committee, led by Stuart Aaronson, MD, Founding Chair Emeritus and Professor of Oncological Sciences and Professor of Medicine.

Selected for funding at $50K each:

Maria Isabel Fiel, MD, Professor of Pathology, and Bachir Taouli, MD,
Professor of Radiology and Medicine
Magnetic Resonance Imaging of Radiomics Quantification for Noninvasive Prediction of HCC Immune Characteristics

Matthew Galsky, MD, Professor of Medicine (Hematology and Medical Oncology) and Urology, and Amir Horowitz, PhD, Assistant Professor of Oncological Sciences
Harnessing Natural Killer Cells for Improving Prognosis and Survival in Genitourinary Cancer Patients

Brett Miles, DDS, MD, Associate Professor of Otolaryngology, and Keith Sigel, MD, Assistant Professor of Medicine (General Internal Medicine and Infectious Diseases)
The Role of HIV in the Immune Microenvironment and Natural History of Low Grad Anal Dysplasia
Jose Javier Bravo-Cordero, PhD , Assistant Professor of Medicine (Hematology and Medical Oncology), has been awarded a Career Catalyst Research grant from the Susan G. Komen Foundation to study how breast cancer cells can lay dormant in the bone, leading to metastasis years after treatment: Targeting cancer cell-ECM interactions to prevent breast cancer metastasis.
Dr. Bravo-Cordero presented a poster at the 2018 meeting of the American Society for Matrix Biology in October : DDR1 Regulates the Construction of a Dormancy-Supportive Niche By Coordinating the Assembly of a ProQuiescence ECM Proteome.
Stefan Balan, MD, Assistant Professor of Medicine (Hematology and Medical Oncology), Chief of Hematology/Oncology at Mount Sinai Brooklyn, Medical Director of the Mount Sinai Brooklyn Ambulatory Infusion Center, and Director of Cancer Network Development, Brooklyn, was honored as a recipient of the Champions and Visionaries of Healthcare Awards on December 3 at the Dyker Beach Golf Course. Launched this year by the Brooklyn Daily Eagle, Brooklyn’s daily newspaper, and its nine sister newspapers, the award recognizes professionals who lead innovative health and social care practice that makes a difference in the lives of patients.
American Society of Hematology
Annual Meeting
The Tisch Cancer Institute (TCI) was well-represented at the 60 th annual meeting of the American Society of Hematology (ASH).
In addition to a strong presence with oral abstract presentations and poster presentations, TCI faculty were also invited to speak at educational sessions, including:

James Ferrara, MD, DSc, on Reining in Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation (selected as a “highlight of ASH”). Already published in Blood Advances 2018, Volume 2, a full article will also be published in Hematology 2018. Dr. Ferrara is the Ward-Coleman Chair in Cancer Medicine and Director of TCI’s Hematologic Malignancies Translational Research Center.

Eirini Papapetrou, MD, PhD, on Induced Pluripotent Stem Cells to Model Blood Diseases and iPS Cell Methods of Hematologic Malignancies at Scientific Program and Meet the Scientist sessions. Dr. Papapetrou is Associate Professor of Oncological Sciences.

Cancer Moonshot℠—Update and Funding Opportunities
A recent blog from Dinah Singer, PhD, Co-Chair, Cancer Moonshot, and the Cancer Moonshot webpages provide updates on scientific initiatives and goals.

These NCI Funding Opportunities highlight research initiatives that align with the efforts of the
Cancer Moonshot.

  • Cancer Immunotherapy Translational Science Network
  • Prevention and Early Detection: Implementation Science
  • Drivers of Childhood Cancers
  • Generation of Human Tumor Atlases
  •  Prevention and Early Detection: Implementation Science
The Different Routes to Metastasis via Hypoxia-Regulated Programs
Study Confirming the Safety Profile of Daratumumab
Ajai Chari, MD , reports in Cancer on an Expanded Access Program in heavily pretreated US patients who have relapsed or refractory Multiple Myeloma.

Encyclopedia of Cancer,
Third Edition
Encyclopedia of Cancer, Third Edition published on October 26. Editors in Chief: Paolo Boffetta, MD , and Pierre Hainaut, PhD . Dr. Boffetta is Professor of Medicine (Hematology and Medical Oncology), Oncological Sciences, and Environmental Medicine and Public Health. This new edition includes the latest on cancer mechanisms, hallmarks of cancer, causes of cancer, prevention and control, diagnosis and therapy, pathology, and the genetics of specific cancers. 
In support of cutting-edge research at The Tisch Cancer Institute that leads to improved patient care, our Biostatistics Shared Resource Facility has launched a Cancer Biostatistics Walk-In Clinic for quick statistical consultation.

The clinic is held on the first and third Wednesday of each month from
 1 to 2 pm in Hess, Room 6-122. 
Lung Cancer Expert
Fred R. Hirsch, MD, PhD, an internationally renowned authority on lung cancer treatment and research, has joined the Mount Sinai Health System as an Endowed Professor in the Department of Medicine (Hematology and Medical Oncology) and Associate Director of Biomarker Discovery for The Tisch Cancer Institute. His research, spanning more than 25 years, has helped identify and validate prognostic and predictive markers for lung cancer outcomes and predictive markers for personalized lung cancer therapies. His research also involves biomarkers for early detection of lung cancer. Previously at the University of Colorado School of Medicine in Denver, Dr. Hirsch is Co-Chair for Southwest Oncology Group’s Lung Cancer Translational Research Committee. He recently completed a five year term as CEO of the International Association for the Study of Lung Cancer. Dr. Hirsch earned his MD and PhD from University of Copenhagen, and also holds a BA in Public Health Administration from Copenhagen Business University.
Medical Director, Mount Sinai Cancer Staten Island
Mahmoud Aly, MD, has been appointed as Medical Director of Mount Sinai Cancer Staten Island and Director of Cancer Network Development for Staten Island and Monmouth County, New Jersey. Prior to joining the Mount Sinai Health System, Dr. Aly was Chief of Hematology/ Oncology at Richmond University Medical Center and also served as director of their fellowship training program. Dr. Aly’s practice has served the Staten Island community for more than 25 years.
Assistant Professor of Surgery,
Dubin Breast Center
Anya Romanoff, MD, has joined the breast cancer service at Mount Sinai as an Assistant Professor of Surgery. She sees patients at the Dubin Breast Center at The Mount Sinai Hospital campus. Dr. Romanoff earned her MD from New York University School of Medicine and competed a residency in general surgery at Icahn School of Medicine at Mount Sinai and a fellowship in breast surgical oncology at Memorial Sloan Kettering Cancer Center. She served as a clinical research coordinator at the Dubin Breast Center during her general surgery residency, and was awarded a Fulbright-Fogarty Postdoctoral Research Award in Public Health which she used to investigate access to breast cancer care in Peru. Dr. Romanoff has a faculty appointment in the Department of Health System Design and Global Health, and is involved in initiatives to help improve access to care and equalize breast cancer outcomes throughout the world.
Medical Student Cancer Interest Group
The Medical Student Cancer Interest Group, Icahn School of Medicine at Mount Sinai, organized a Cancer Research Panel on November 7. Attended by close to 40 medical students, the panel featured faculty conducting basic, translational, and clinical research in cancer reflective of TCI’s programmatic strengths in Cancer Biology, Cancer Immunology, Cancer Clinical Investigations, and Cancer Prevention and Control. Eight faculty members from TCI provided advice about needed skills and knowledge for pursuing research and how to choose a research mentor.

A survey of members of the Medical Student Cancer Interest Group, conducted in advance of the panel, indicated that 50 percent of students were interested in lab/bench research, 75 percent in outcomes research, and 90 percent in clinical trials.

Janice Gabrilove, MD, FACP, provides faculty guidance to the Medical Student Cancer Interest Group. Dr. Gabrilove holds many education roles, including Associate Director of Education and Training for the Tisch Cancer Institute and Director of Clinical Research Education Programs at the Icahn School of Medicine at Mount Sinai and the Graduate School of Biomedical Sciences.
Novel Therapy for Multiple Myeloma
Episode 7 of  Mount Sinai Future You  features an artist’s battle with late
stage, drug resistant multiple myeloma. Under the care of Samir Parekh, MBBS, Director of Multiple Myeloma Translational Research, the patient received novel therapy that helped him achieve his dream of finishing a painting that had been in the works for 40 years.

Pictured, from left: Samir Parekh, MBBS, Nicholas Palmisano, Ramon Parsons, MD,PhD
Mount Sinai's Mobile Mammography Program
Mount Sinai’s Mammography Van, funded through a grant from New York State to provide women with access to breast cancer screening in their communities, began operations in October. To date, the van has been to multiple sites in Manhattan, including the The Samuel J. Friedman Health Center for the Performing Arts (a program of The Actors Fund and Mount Sinai Doctors), the Family Health Center of Harlem , Settlement Health , Carter Burden Network , and others. The van, which can provide more than 30 mammograms a day, will be scheduled at sites throughout the five boroughs.
Cancer Screening Awareness
A SCRUB OUT CANCER campaign in the perioperative area of The Mount Sinai Hospital was launched in October. Under the leadership of Benjamin Salter, DO , Assistant Professor of Anesthesiology, and Lucy Duffy, RN, Vice President of Perioperative Services, the campaign aims to raise awareness about the benefits of cancer screening. 
Pictured: Benjamin Salter, DO, right, and Lucy Duffy, RN, second from right, with organizing team members of the “Scrub Out Cancer” campaign.
New Program for Families: Bereavement Support Groups
A six-week program for those who have lost
a loved one to cancer

Ruttenberg Treatment Center
Every other Wednesday from 4 to 5 pm, starting January 16
For information, contact Anna Gribetz, 212-824-8762

The Blavatnik Family – Chelsea Medical Center at Mount Sinai
Every other Wednesday from 9:30 to 10:30 am, starting March 6, 2019
For information, contact Samantha Rappaport, 212-604-6095
Progress in Immunotherapy
Nina Bhardwaj, MD, PhD, Director of Immunotherapy at The Tisch Cancer Institute, participated in a “What’s Next in Immunotherapy” panel at The Atlantic’s “People v. Cancer”— #PeopleVCancer on November 14. “What’s terribly exciting is the approval of many checkpoint inhibitors, antibodies that reverse immune suppression in the tumor microenvironment and which have made a dramatic impact on the treatment of so many patients with cancer.”

Photo Credit: Kristoffer Triplaar
International Outreach
In August, Michail Shafir, MD, MPH, FACS , Clinical Professor of Surgery and Oncological Sciences, chaired an International Clinical Trials Workshop (ICTW), sponsored by the American Society of Clinical Oncology (ASCO) International and in collaboration with the Colombian Society of Hematology and Oncology. The ICTWs support cancer research in low- and middle-income countries by developing research skills among early-career researchers. Ninety-seven percent of respondents to the workshop evaluation said that participating in the workshop increased their motivation to do research.

In November, Dr. Shafir participated in an assessment mission on cancer programs in Paraguay, sponsored by ASCO International and the Union for International Cancer Control (UICC).
Dr. Shafir is second from right in photo.
Upcoming Cancer Symposia at Mount Sinai
Full-day symposium, sponsored by the Mount Sinai Liver Cancer Program (first NCI-recognized liver cancer program in the United States)

Program Director:
Professor of Medicine
Co-Director, Mount Sinai Liver Cancer Program

Friday, December 14
3rd Annual International Prostate Cancer and Urologic Oncology Symposium

December 13-15
Stern Auditorium
1468 Madison Avenue

Course Director: Ash Tewari, MBBS, MCh, Professor of Urology and Chair, Milton and Carroll Petrie Department of Urology

Course Co-Director: Ketan K. Badani, MD, Professor of Urology
Register with special code to waive the fee: MSHS18
For more information, contact Margaret Wolf
Cancer is front and center in a new Mount Sinai Health System ad campaign built around the theme: “Which hospital you choose can make all the difference in the world.” The ads appear on the Long Island Rail Road, Metro-North, and New York City subway and buses. Examples of ads to date:
Mount Sinai News

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    TCI Connections     is a monthly publication of The Tisch Cancer Institute.
Ramon Parsons, MD, PhD, TCI Director
Co-editors: Janet Aronson and Rhaisili Rosario
Past issues of    TCI Connections    are available on the TCI website.