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DID YOU KNOW that over an average follow-up of 15.4 years, riboflavin, vitamin B6, and folate intake were associated with a significantly reduced risk of disabling dementia, according to a study from the European Journal of Clinical Nutrition?

On the topic of dementia, older adults who did computerized speed-training exercises plus booster sessions had 25% lower risk of dementia diagnosis over 20 years, as reported in Alzheimer’s & Dementia. The effective training required 10 initial sessions over 6 weeks, plus booster sessions at 1 year and 3 years. Skipping the booster sessions erased all benefits, even for those who completed initial training.

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Steve: For decades, Alzheimer's research chased a single culprit - the sticky amyloid-beta plaques that build up in the brain. A growing number of researchers now argue that's because Alzheimer's was never a one-cause problem. A major review in Science China Life Sciences frames it as the combined result of amyloid buildup, tangled Tau protein, genetics, aging, and whole-body health (including blood sugar balance), and calls for treatments that hit several of these targets at once rather than betting on any single one.

While the drug science has greatly underwhelmed, some of the most encouraging findings are about what we can do ourselves, starting with keeping the mind active. A study of nearly 2,000 older adults published in Neurology found that people who stayed intellectually engaged across their whole lives - reading, writing, learning languages, visiting libraries and museums - developed Alzheimer's about five years later, and mild cognitive impairment about seven years later, than those with the least mental stimulation. Remarkably, these benefits held even in people whose brains already showed amyloid and Tau changes at autopsy. A separate study of nearly 4,000 adults published in Scientific Reports reinforced the theme, finding that brain health scores actually improved over three years - in participants ranging from their twenties to their nineties. The strongest predictor of improvement wasn't age or education; it was simply how consistently people engaged with brain-healthy habits.

The body matters as much as the mind. Research in Neurology that used post-World War II British sugar rationing as a natural experiment found that people whose sugar intake was limited during their earliest months of life (in the womb and infancy) had a meaningfully lower risk of dementia decades later - much of it explained by better long-term metabolic health, like lower rates of diabetes and high blood pressure. A large lifestyle trial published in JAMA Network Open showed that a structured program combining exercise, a brain-friendly diet, cognitive training, and social connection helped preserve white matter in the brain - with the clearest benefit in people who started before age 70, underscoring that earlier is better.

Alzheimer's is complex and requires more proven therapies on the medical side, but lifelong learning, sound nutrition, movement, and social connection can all be done right now on the personal side.

Amazon 89.95 (120 caps)

Nutritional Concepts 60.38

Savings: 29.57!!

Amazon 34.50 (60 caps)

Nutritional Concepts 23.20

Savings: 11.30!!

Amazon 74.95 (270 tabs)

Nutritional Concepts 43.94

Savings: 31.01!!

While Amazon is the frequent example, we found similar price disparities with many online retailers. We are authorized retailers of all of our brands while many online retailers are not. Our supplements come directly from the manufacturer and never encounter a third of fourth party.

PureInsight (formerly Genomics) harnesses the science of nutrigenomics so you can understand the relationship between your genes, nutrition, and wellness at the deepest level. Covering 72 genes in 11 trait categories, we've used Pure Insight since 2015 to help clients live longer with better quality of life.

How to Get Started

1. Order a genetic kit directly from Ancestry.com (AncestryDNA for $99) or 23andMe.com (Basic Ancestry for $99) and send back your saliva specimen. When your results are ready, request that we set up a PureInsight account for you. We just need your full name, email address, and date of birth. You will receive an email invitation from PureInsight with a link to set up your account and instructions for how to upload your Ancestry data. You will receive a confirmation from PureInsight when your report is ready and we can then set up an appointment to go over your results.

Twice Weekly eNewsletters with Tons of Extra Content 

Long-form issues on Mondays and Wednesdays address all aspects of wellness including nutrition, mental and emotional health, physical activity, cooking, brand awareness, dietary supplements, medical breakthroughs, and much more.

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Only paid members have exclusive, password protected access to our 48 title Action Plan Library, Natural Foods Shopping List (updated quarterly), and the most recent 100 issues of our email newsletter.

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We keep track of your points automatically. Discounts are automatically applied to your orders or you will be sent a promo code if you order online.

250 points = $5 off

500 = $10

750 = $10

1000 = $15

1500 = $15

2000 = $15

2500 = $20

Each 1000 thereafter = $25

Rewards can only be applied to dietary supplements. NCI Well Rewards start January 1 and ends December 31, 2026. We reserve the right to alter or cancel this offer at any time.

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Bonnie, Steve, Lilo, Cindy, Diana, Sally, and Piper (not pictured)

Nutritional Concepts Inc.

155 Revere Drive, Suite 11

Northbrook, IL 60062

Phone 847-498-3422

Text 847-497-0902

Hours Of Operation

Monday through Friday 9AM to 5PM

Saturday 9AM to 2PM