Quarterly Newsletter, October 2022
What's going on with POPI?
The past year for POPI has been one of awareness, promotion and opportunity.

From the 3rd annual 2021 McGraw Opioid Innovator Awards, the 1st annual Walk for POPI 5K event and National Opioid and Substance Awareness Day, POPI has been full speed ahead with carrying it's mission!

Read on for details on this year's events and other opportunities for funding and education.
Past Year Highlights
McGraw Opioid Innovator Awards
2021 Marked the 3rd Annual McGraw Family Opioid Awards and Shark Tank Event. The generous support of the McGraw family made way for two very important projects in opioid and pain innovation research to gain its bearings.

1st Place $50,000
Primavera Spagnolo, MD, PhD
Department of Psychiatry & Connors Center for Women's Health and Gender Biology

Project: Endocannabinoids and Opioids: Investigating the effects of palmitoylethanolamide in stress-induced craving, hyperalgesia and negative affect in opioid use disorder

For information on other finalists and their projects Click Here.
2nd Place: $25,000
Anupama Mehta, MD
Medical Director, Burn Program
Department of Anesthesiology, Perioperative and Pain Medicine
Project: Can Olfactory Virtual Reality reduce opioid consumption and improve tolerance in burn patients undergoing dressing changes? A pilot study

The Inaugural Walk for POPI 5K event was held on April 30, 2022 at Boston's Historic Franklin Park. The funds raised for this event help support the POPI's administrative functions and the overall mission of POPI to support it's innovators. This first year event featured BWH and MGH volunteers and participants, free covid test kit give aways, physical therapy sessions with Dimock's Bay State Physical Therapy, LIVE MUSIC and more!

POPI's goal is to make this an annual event. It's not too late to give! Click HERE to GIVE.
Visit our POPI DONATE PAGE HERE to support year round.
National Opioid and Substance Use Awareness Day 2022 - NOSAD

The 3rd Annual National Opioid and Substance Awareness Day (NOSAD) was held September 13th from Noon- 3p.m, Hosted by POPI and BCORE, this virtual event featured remarks from Former Congressman Patrick Kennedy, a panel discussion from HHS, CDC and SAMSHA, presentations from BWH, and testimonials from persons with lived experience. Free online screenings for Substance Use and Mental Health were available to attendees. This event was free and open to the public!
Please visit our landing page HERE for more information about the event and speakers.

View Full Event Below
In the News
Uptick in Fentanyl and OUD Deaths
The aftermath of COVID-19 has cautioned providers and community leaders to zoom in on
the rise in fentanyl and opioid use deaths.

Amongst adolescents, Between 2019 and 2020, overdose mortality increased by 94.03% and from 2020 to 2021 by 20.05%

Drug overdose death rates among Black people living in the United States rose significantly from 2019 to 2020, outpacing the overdose death rates of White people for the first time in over 20 years.

For more information visit attached links or visit cdc.gov for more provisional data.
Federal and Private Funding Opportunities
NOSI seeks applications that will test multifaceted implementation strategies for evidence-based clinical guidelines on opioid prescribing for pain management, in order to (1) increase guideline-concordant clinical care behaviors; (2) generate measurable, timely, and sustainable changes in clinical behavior across entire healthcare systems; and (3) improve patient outcomes.
(FOA) Number: NOT-DA-20-038
Due Date: January 7, 2023
The purpose of this Funding Opportunity Announcement (FOA) is to encourage epidemiological, clinical, and translational research that will increase our understanding of the natural history, prevalence, biological mechanisms, psychological variables, and clinical risk factors responsible for the presence of multiple chronic pain conditions in people with pain. The main objective of this FOA is the formation of research groups with interests bridging expertise in pain mechanisms with translational and clinical expertise to address important unresolved questions about overlapping pain conditions.
(FOA) Number: NOT-DA-20-004
Due Date: May 8, 2023
Specifically, NIDA seeks applications for multi-project RM1 Opioid Use Disorder Quality Measurement and Management Research Centers (OUD-QM2RCs). OUD-QM2RCs will involve researchers and a partner with a deployed or in-development quality measurement strategy for opioid use disorder treatment that rigorous, scientific research could substantially advance. The ultimate goal is the creation of feasible, efficient quality measurement systems that provide meaningful information to help patients, families, and payors fairly compare and select providers and to help clinicians and providers improve patient outcomes. Activities should support the acceptability of the quality measurement and management system to patients, clinicians, and providers; the feasibility, scalability, and sustainability of the system; and equity in clinician/provider selection and treatment delivery.
(FOA) Number: RFA-DA-23-046
Due Date: January 2, 2023
For more OUD and Pain related funding opportunities visit Funding
Featured Innovator Publications
Maria Edelen, PhD - Patient Reported Outcomes Value and Experience (PROVE) Center, Department of Surgery

Pain is highly prevalent among patients in post-acute care (PAC) settings and can affect quality of life, treatment outcomes, and transitions in care. Routine, accurate assessment of pain across settings is important for pain management and care planning; however, existing PAC assessment instruments do not assess patient pain in a standardized manner. Dr. Edelen developed and tested a set of pain interview data elements for use across PAC settings that assesses six pain constructs: presence; frequency; interference with sleep; interference with rehabilitation therapies; interference with daily activities; worst pain; and pain relief from treatments/medications.
Richard Urman MD, MBA - Anesthesiology Perioperative and Pain Medicine

Dr. Richard Urman conducted and published research on the racial and ethnic disparities within OUD. Hispanic and Latin populations have the most significant proportion of youth with OUD and often lack culturally appropriate translation services that allow for effective treatment to combat the disorder. Native Americans have the second highest rate of OUD and often receive care in communities that lack funding for healthcare. African Americans tend to suffer from the criminalization of OUD and are less able to seek treatment. While White patients traditionally receive more pain management, they are also at higher risk of developing OUD.
Beverly Philip, MD - Anesthesiology, Perioperative and Pain Medicine

The US Health and Human Services Pain Management Best Practices Inter-Agency Task Force initiated a public-private partnership which led to the publication of its report in 2019. The report emphasized the need for individualized, multimodal, and multidisciplinary approaches to pain management that decrease the over-reliance on opioids, increase access to care, and promote widespread education on pain and substance use disorders. The Task Force specifically called on specialty organizations to work together to develop evidence-based guidelines. In response to this report's recommendations, a consortium of 14 professional healthcare societies committed to a 2-year project to advance pain management for the surgical patient and improve opioid safety.
Eli Sayegh, MD - Orthopedic Surgery
Christopher Cheung, MD - Anesthesiology, Perioperative and Pain Medicine

Postoperative pain is a common but often inadequately treated condition. Enhanced recovery pathways (ERPs) are increasingly being utilized to standardize perioperative care and improve outcomes. ERPs employ multimodal postoperative pain management strategies that minimize opioid use and promote recovery. While traditional opioid medications continue to play an important role in the treatment of postoperative pain, ERPs also rely on a wide range of non-opioid pharmacologic therapies as well as regional anesthesia techniques to manage pain in the postoperative setting. This article reviews the current evidence and knowledge gaps pertaining to commonly utilized modalities for postoperative pain management in ERPs.
To learn read more publications by Brigham and Women's POPI Innovators visit - Publications
Upcoming Events

4th Annual McGraw Opioid Innovator Awards
Tuesday, October 25th
4 p.m. - 6 p.m.
Click HERE to RSVP!

View this year's competing innovators HERE
Walk for POPI 5K
September 2, 2023

POPI is gearing up for it's 2nd Annual Walk for POPI 5K event. The location is still TBD.

This year's event will be held on September 2nd 2023 to help jumpstart Substance Use Awareness Month.

Please stay tuned to the POPI events page for more information on the logistics for this event.

Remember it's never too late or early too donate!!

Click HERE for the 2022 donation page andHERE for the general POPI donate page.

We are looking forward to seeing you walk with us next year!


The next POPI Meeting will be held
Wednesday October 12th
3:00PM - 4:00 PM
Hale Building Floor 2
VTC - 2006b Conference Room

If you would like to attend please RSVP to the right.

Complete a Brief Survey to Help us make POPI better!

For additional information Contact:
POPI Quarterly and Strategic Planning Meeting
Hale Building 2nd Floor, Room - VTC - 2006b Conference Room

10/12/22 3:00pm - 10/12/22 4:00pm

Updates on POPI strategic plan and timeline line of events.
I'll be there!
I can't make it
BWH Program in Opioid and Pain Innovation (POPI)- 2022