May 2021
Tumor marker may help overcome endocrine treatment-resistant breast cancer

A study led by Svasti Haricharan, Ph.D., has identified a tumor marker that may be used to predict which breast cancer patients will experience resistance to endocrine therapy. The research offers a new approach to selecting patients for therapy that targets HER2—a protein that promotes the growth of cancer cells—to help avoid disease relapse or progression of endocrine-sensitive disease. The research was published in Nature Communications.

Study supports targeting lipid kinases as potential therapy for cancer

By taking a deep dive into lipid kinases, Brooke Emerling, Ph.D., discovered that they are essential to maintaining the energy that cells need to grow and survive. The findings support efforts to target these proteins for diseases that demand excess energy, such as cancer. The study was published in Developmental Cell.

Sanford Burnham Prebys joins call for action to get HPV vaccinations back on track

"The HPV vaccine could prevent more than 90% of cancers caused by the virus, and getting vaccinated can prevent many of these cancers later in life," said Ze'ev Ronai, Ph.D., director of our NCI-designated Cancer Center. The COVID-19 pandemic has slowed vaccination rates, and our Institute joined the NCI's initiative urging physicians, parents and young adults to get HPV vaccinations back on track.

Women at (science) work

Meet three Sanford Burnham Prebys scientists who discuss their careers, successes and what inspires them as women to continue challenging but rewarding careers in biomedical research. 

Insights: An end for Alzheimer's Disease

Of the top 10 causes of death in the United States, Alzheimer's disease is the only one for which no effective or preventive treatment exists. Join us we explore the root cause of the disease and share information about the promise of new therapeutics. The event on Tuesday, June 22, from 1:00 to 2:00 p.m. PT, will be followed by a Q&A session to give you an opportunity to connect with our scientists and have your questions answered.

Immunotherapy – helping our bodies cure cancer

Immunotherapy—empowering our own immune system to kill tumors—has revolutionized the treatment of cancer. However, the treatment doesn't work for everyone. Join us on Tuesday, July 13, from 1:00 to 2:00 p.m. PT, to hear from scientists on the leading edge of immunotherapy research.

Stem Cells – the future is now

It wasn’t long ago when we first heard about the promise of stem cells. They were the wave of the future. Now we are on the path to reap the benefits of our breakthrough research and improve human health. Join us on Thursday, August 5, from 1:00 to 2:00 p.m. PT, for a vibrant discussion on the future of stem cell therapies.

Insights: New hope for an HIV cure

Nearly 40 million people around the world are living with HIV. Antiviral therapy has increased the life spans of people with HIV, but it isn't a cure. Scientists at Sanford Burnham Prebys have created a drug that appears effective at eliminating HIV once and for all. This event included scientists, leaders from the LGBTQIA+ community and HIV patients discussing this novel approach to cure HIV.

Staying strong as we age

Muscle degeneration can occur in many conditions, such as muscular dystrophies, HIV and even aging. Muscle stem cells offer a tremendous hope for future therapies, but there is still much we need to understand. Alessandra Sacco, Ph.D., shared her research on the topic at this presentation held in partnership with the Fleet Science Center.

Infectious disease expert Sumit Chanda debunks myths that COVID-19 vaccinations are to blame for India's recent COVID-19 surge. "There's actually an inverse correlation between those people who got the vaccine and those people who are getting sick," said Chanda.

Sanford Burnham Prebys receives funding from the Leukemia and Lymphoma Society (LLS) in a fundraising campaign inspired by 6-year-old Liam Vest. Liam won his four-year battle with leukemia and was the 2021 LLS Boy of the Year.

At Sanford Burnham Prebys, we're passionate about finding bold new ways to treat disease, and we recognize the importance of sharing our discoveries with the public—especially during this unprecedented time. Find out where and when you can "meet" our scientists virtually and learn about their research in this community event calendar.
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