The RNA Transcript, April 12, 2021
Department of Neurology, University of Michigan Medical School

“There is so much to learn in school,
and there is nothing else I’d rather be doing.”

A Ph.D. dissertation is a huge accomplishment, resulting from four, five or more years of intense research and training. To become a Ph.D. is a remarkable challenge both scientifically and intellectually that requires a deep personal and emotional commitment. A doctoral defense is not only the culmination of years of hard work, but it also raises the question of “what’s next for me?” after years on the schooling and training track.

On March 22, 2021, Ahmed Malik defended his Ph.D. thesis in Dr. Barmada’s lab, Department of Neurology, University of Michigan Medical School. For him, the “what’s next?” question finds answers in his passionate quest for knowledge and bioscience exploration. “There is so much to learn in school, and there is nothing else I’d rather be doing,” he said only a few days after defending his Ph.D. thesis.


Tuesday, April 13, 3:00 pm EST | Harvard Medical School Initiative for RNA Medicine Seminar 
ZOOM, Password: 759932; Meeting ID: 922 0571 6546

“Regulation of mRNA translation and decay”
David Bartel, Ph.D., Professor of Biology, MIT, Member, Whitehead Institute Investigator, Howard Hughes Medical Institute
Tuesday, April 13, 4:00 pm EST | U-M Center for Cell Plasticity and Organ Design, and Department of Human Genetics

"RNA regulation in proteotoxic stress and genetic neurological disorders”
Stephanie Moon, Ph.D., Assistant Professor of Human Genetics Faculty Scholar of the Center for RNA Biomedicine Affiliate Faculty, Biological Chemistry, University of Michigan
Monday, April 19, 4:00 pm ET | U-M Center for RNA Biomedicine, RNA Innovation Seminar Series

“Structural insights into mRNA translation initiation in humans”
Jailson (Jay) Brito Querido, Ph.D., Postdoctoral Scientist, MRC Laboratory of Molecular Biology, Cambridge, UK

Dr. Querido has been featured in the Member Spotlight Series of The RNA Society.

 
Contact Elisabeth Paymal for press releases and blog articles of your upcoming top journal publications.

Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below are recent highlights.
Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders

Key Points:
  • An innovative digital assay technology enables rapid, point-of-care measurement of multiple protein biomarkers in blood.
  • Continuous monitoring of protein blood biomarker profiles is shown for critically ill human patients with a digital assay.
A glomerular transcriptomic landscape of APOL1 in Black patients with focal segmental glomerulosclerosis, Michelle. M. McNulty, Damian Fermin, Felix Eichinger, Dongkeun Jang, Matthias Kretzler, Noel Burtt, Martin R. Pollak, Jason Flannick, David J. Friedman, Nephrotic Syndrome Study Network (NEPTUNE), Matthew G. Sampson

Abstract:
Apolipoprotein L1 (APOL1)-associated focal segmental glomerulosclerosis (FSGS) is the dominant form of FSGS in Black people. There are no targeted therapies for this condition, in part because the molecular mechanisms underlying APOL1’s pathogenic contribution to FSGS are incompletely understood. ....
For Fun
The precise study of color as generalized from visible light to all bands of the electromagnetic spectrum is called...
(answer next week!)
Spectroscopy
Spectrography
Chromatography
Impressionism
LAST WEEK QUESTION:
Approximately, how much of the weight of a human cell is RNA?

ANSWER:
About 5% of the weight of a human cell is RNA. Only about 1% of a cell consists of DNA. (source)
(source)

RNAi Post-Doctoral Research Fellow – April 7, 2021
Position Overview A postdoctoral research position employed by Terminix in collaboration with the USDA National Wildlife Research Center (NWRC). The position will be based in Fort Collins, CO. The position is under the toxicology research group at NWRC which is responsible for developing and testing novel toxicants to control vertebrate pest wildlife species to reduce human/wildlife conflict and protect agriculture. The NWRC Principle Investigator will coordinate and oversee research activities. Research will include laboratory studies on RNAi efficacy and timeline of effects, off-target effects, and possible immune activation. Further studies using animal models will be done to determine in-vivo efficacy. MORE INFO APPLY HERE
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