The RNA Transcript, January 4, 2021 |
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Only a couple of weeks after defending her Ph.D. thesis in November, Sarah Owen, a graduate student in Chemical Engineering in Dr. Sunitha Nagrath’s lab, landed her dream job. “It all went very fast,” she explained, “I had a seven-hour zoom interview on Thursday, and they offered me the job the following Monday!”
In January 2021, Owen will join Seagen, a biomedical company that seeks to improve the lives of people with cancer through innovative targeted therapies. As a Process Scientist, she will develop novel ways to test and characterize drug compounds after their R&D phase, and before clinical trials.
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2,021 FOLLOWERS to WELCOME 2021! @umichRNA
Thank you to all our followers, colleagues, and friends for your comments, likes, and retweets! To celebrate 2021, we are grateful to our 2,021 followers!
Click below to follow and share with your RNA community!
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Tuesday, January 5, 3:00 pm EST | Harvard Medical School, Initiative for RNA Medicine Seminar
“Role and mechanism of action of miRNAs in skeletal development and dysplasias”
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Wednesday–Friday, January 6–8, 2021 | Intersections Science Fellows Symposium
This multi-institutional symposium will showcase the work of mid- to late stage postdocs in biomedical science on January 6-8th, 2021, virtually. This exciting symposium aims to showcase the science of outstanding postdocs specially those who are from backgrounds historically underrepresented in academia to advance diversity, equity and inclusion in academic science.
For more information, please visit our website and follow us on Twitter @InterSciFellows.
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“Ribosome collisions and sites of quality control revealed by ribosome profiling”
“CRISPR screening to identify biologically important microRNA targets”
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Monday, January 25, 4:00–5:00 pm EST | U-M Center for RNA Biomedicine, RNA Innovation Seminar Series
Title TBA
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5th RNA SYMPOSIUM SCHEDULE
Thursday, March 25, 2021
11:00-11:05 / Welcome
12:00-12:10 / short break
1:05-1:35 / Data Blitz (part 1)
2:30-2:30 / Brief close
Friday, March 26, 2021
11:00-11:05 / Welcome
12:00-12:10 / short break
1:05-1:35 / Data Blitz (part 2)
1:35-2:25 / Panel
2:25-2:30 / Closing
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Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below is a recent highlight.
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High-throughput screening to discover inhibitors of the CarD·RNA polymerase protein–protein interaction, Stefan, M.A., Velazquez, G.M. & Garcia, G.A. in Mycobacterium tuberculosis. Sci Rep 10, 21309 (2020). https://doi.org/10.1038/s41598-020-78269-3
Significance
We expect that the development of a new and improved anti-TB compound with a novel mechanism of action will relieve the burden of resistance. This CarD FP assay is amenable to HTS and is an enabling tool for future novel therapeutic discovery.
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Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, Yujing Song, Erin Sandford, Yuzi Tian, Qingtian Yin, Andrew G. Kozminski, Shiuan-Haur Su,Tao Cai, Yuxuan Ye, Meng Ting Chung, Ryan Lindstrom, Annika Goicochea, Jenny Barabas,Mary Olesnavich, Michelle Rozwadowski, Yongqing Li, Hasan B. Alam, Benjamin H. Singer,Monalisa Ghosh, Sung Won Choi, Muneesh Tewari, Katsuo Kurabayashi, Blood blood.2019004399. https://doi.org/10.1182/blood.2019004399
Key Points
- An innovative digital assay technology enables rapid, point-of-care measurement of multiple protein biomarkers in blood.
- Continuous monitoring of protein blood biomarker profiles is demonstrated for critically ill human patients with a digital assay.
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