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November 20, 2023

TODAY - RNA Innovation Seminar Series


“The Invisible Dance of CRISPR-Cas9 through Molecular Space and Time”


George Lisi, Ph.D.

Thomas J. & Alice M. Tisch Assistant Professor

Department of Molecular Biology, Cell Biology & Biochemistry

Brown University


Monday, November 20, 4:00 PM - 5:00 PM ET

BSRB ABC Seminar Rooms, Hybrid Link

Affiliated Seminars

Penn Institute for RNA Innovation, University of Pennsylvania


Title: TBA

Speaker: Mohamad-Gabriel Alameh

Co-Director of the mRNA Core, University of Pennsylvania, PA, USA


Moderator: Russell Roberts, Senior Communications Specialist, University of Pennsylvania, PA, USA


Wednesday, November 22, 2023, 4 PM ET  Zoom Registration

Oral Defenses

U-M Oral Dissertations

"Development of Multidisciplinary Methods for Identifying Small Molecules With FMN Riboswitch Binding Capacity"


Liz Tidwell, Biophysics

Advisor: Markos Koutmos


November 27, 2023 10:00 AM

RACKHAM EAST CONFERENCE ROOM, FOURTH FLOOR HYBRID PASSCODE: FMN

"Evolutionary Constraints and Potential of the Influenza A Virus RNA-dependent RNA Polymerase"


Yuan Li, Microbiology & Immunology

Advisor: Adam Lauring



November 30, 2023, 1:00 PM

AUDITORIUM 3330, MED SCI 1 and Zoom

For more information and to view the full schedule of upcoming U-M Oral Defenses, please visit the Rackham Graduate School Oral Defenses website.

RNA SOCIETY

New Blog Post: Lexogen RNA Expertise Blog Series

November 8, 2023


Lexogen’s LUTHOR HD Application Note has been published in Nature: Advancing High-Definition Single-Cell RNA Sequencing

In the News

Stephen Goutman, Stuart Batterman, and Eva Feldman publish paper on blood test to assess ALS development risk

Recent study shows how examining toxins and pollutants in blood samples can measure risk of ALS, or amyotrophic lateral sclerosis, development.


RNA plays a pivotal role in ALS neurodegeneration. Could this hold promise for RNA therapeutic development? Read more from Sami Barmada, M.D., Ph.D.

Meetings

There's Still Time to Join Us for the Joint Meeting on RNA Modifications and Regulatory RNAs

Click the photo above to download the program flyer.

Keystone Symposia's joint meeting on RNA Modifications in Health and Disease and Regulatory RNAs: Emerging Mechanisms is coming up this December 12-15 in Banff, AB, Canada. Even though most deadlines have passed, we want to let you know that it's not too late to register for two conferences for the price of one!


For more information and to register, visit: Keystone Symposia

HIRM 2024 Symposium, April 25 - Save the Date

2024 Symposium

 

HIRM 10 Year Anniversary Symposium

Thursday, April 25, 2024

 

Joseph B. Martin Conference Center

77 Avenue Louis Pasteur

Boston, MA 02115


Our members' publications are available through Altmetric. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights. Bold denotes CRB member.

Hatfield BM, Weidmann CA, Weeks KM. Measuring Proximity-Mediated Function of mRNA Regulatory Proteins by Engineered Tethering. Methods Mol Biol. 2024;2723:143-159. doi: 10.1007/978-1-0716-3481-3_9. PMID: 37824069; PMCID: PMC10621603. https://doi.org/10.1007/978-1-0716-3481-3_9

Goutman SA, Boss J, Jang DG, Mukherjee B, Richardson RJ, Batterman S, Feldman EL. Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort. J Neurol Neurosurg Psychiatry. 2023 Sep 27:jnnp-2023-332121. doi: 10.1136/jnnp-2023-332121. Epub ahead of print. PMID: 37758454. https://doi.org/10.1136/jnnp-2023-332121

Smith TJ, Giles RN, Koutmou KS. Anticodon stem-loop tRNA modifications influence codon decoding and frame maintenance during translation. Semin Cell Dev Biol. 2024 Feb 15;154(Pt B):105-113. doi: 10.1016/j.semcdb.2023.06.003. Epub 2023 Jun 28. PMID: 37385829. https://doi.org/10.1016/j.semcdb.2023.06.003

Wilhelm CA, Mallik L, Kelly AL, Brotzman S, Mendoza J, Anders AG, Leskaj S, Castillo C, Ruotolo BT, Cianfrocco MA, Koutmos M. Bacterial RNA-free RNase P: structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. J Biol Chem. 2023 Oct 6:105327. doi: 10.1016/j.jbc.2023.105327. Epub ahead of print. PMID: 37806495. https://doi.org/10.1016/j.jbc.2023.105327

Hou Q, Chatterjee S, Lund PE, Suddala KC, Walter NG. Single-molecule FRET observes opposing effects of urea and TMAO on structurally similar meso- and thermophilic riboswitch RNAs. Nucleic Acids Res. 2023 Oct 19:gkad866. doi: 10.1093/nar/gkad866. Epub ahead of print. PMID: 37855661. https://doi.org/10.1093/nar/gkad866

U-M CRB Faculty - remember to share your stories with us!

Don't forget to send us your posts and we'll help you get the word out about exciting developments on the RNA Research & Therapeutics front to help grow engagement.


Fill out the Communication and News Update Form located under the "Resources" tab on the home page of our website, and we'll assess how your story can best be promoted!

Job Postings

Postdoctoral Fellow UMich Department of Pathology


The laboratory of Dr. Sethu Pitchiaya, Assistant Professor, Department of Urology, Department of Pathology at the University of Michigan seeks to hire an enthusiastic Postdoctoral fellow to work on exciting projects related to mammalian stress response mechanisms. Learn more.

University of Michigan BIBC Tenure Track Faculty Search


The University of Michigan has launched a Tenure Track Faculty Search for the BioInnovations in Brain Cancer Initiative (BIBC), led by Center for RNA Biomedicine Faculty Member Dr. Maria G. Castro and Dr. Steven Schwendeman. Learn more.

The University of California Irvine (UCI), Department of Ophthalmology

Full-Time Position


Inviting applicants focused on the development of genetic engineering and genome editing technologies. Learn more.

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan


Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

Research Technician and Post-Doctoral Research Fellow | Fred Hutchinson Cancer Center | The Lapointe Lab


Seeking to fill two positions: Research Technician and Post-Doctoral Research Fellow. Learn more.

Research Technician - Yadavalli Lab



Seeking full-time technician or research scientist to perform cutting-edge research in RNA biology using high-throughput sequencing methods. Learn more.

Postdoctoral Position - Maquat Lab


A postdoctoral position is open. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology. Learn more.

Postdoctoral Position - Cooperman Laboratory


Seeking postdoctoral student with a strong interest in understanding the mechanism and regulation of cytoplasmic eukaryotic protein synthesis. Learn more.

Recruitment Opportunities

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website

Save the Date

2024 RNA Symposium | March 8, 2024

Unmasking the Power of RNA: From Structure to Medicine

The 8th annual symposium will take place on Friday, March 8, 8:30 a.m. - 4:00 p.m. in the A. Alfred Taubman Biomedical Science Research Bldg., Kahn Auditorium at 109 Zina Pitcher Place in Ann Arbor, Michigan. Registration opens in two weeks on December 4.


Speakers: Drew Weissman, M.D., Ph.D., University of Pennsylvania, 2023 Nobel laureate for Physiology or Medicine for his work on mRNA vaccines; Victoria D'Souza, Ph.D., Harvard University; Brenton R. Graveley, Ph.D., University of Connecticut; Leemor Joshua-Tor, Ph.D., Cold Spring Harbor Laboratory; and Peter Todd, M.D., Ph.D., University of Michigan


Download the 2024 RNA Symposium Flyer

To share your news and comments, please contact

rna-communications@umich.edu

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