The RNA Transcript, October 3, 2022 | |
Explore Single Molecule Imaging at the SMART Center | |
The SMART (Single Molecule Analysis in Real-Time) Center is an NSF-seeded, shared-use facility providing university researchers with single molecule detection and manipulation tools to track and analyze biomolecules with unprecedented detail. The SMART Center provides access to state-of-the-art instrumentation, including single molecule spectroscopy and imaging, laser tweezers, and atomic force microscopy; as well as experienced support in experimental planning and analysis.
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SMART Center Services include:
- Single molecule fluorescent imaging and tracking
- Fluorescence lifetime imaging
- Fluorescence correlation spectroscopy
- Force spectroscopy
- Atomic force microscopy
- Optical tweezers
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Areas of expertise:
- Single molecule techniques
- Fast high-resolution fluorescent imaging
- Single particle fluorescent tracking
- Fluorescence lifetime imaging
- Force spectroscopy
- Experimental planning
- Single molecule data analysis
- Training
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U-M Oral Dissertation Defense | | |
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Development and Analytical Characterization of Lipid-Based Nanoparticles
Minzhi Yu, advisors: Anna Schwendeman and Steve Schwendeman
Monday, October 3, 2022
1:00 - 2:00 p.m.
NCRC Building 10-G065
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Harvard Initiative for RNA Medicine - RNA Technology Showcase | | |
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Removing bottlenecks in mRNA research: Accelerating mRNA workflows through the use of push-button automated solutions, Adam Sanford, Codex DNA
Snapshot of miRNA:mRNA interactome using miR-eCLIP
Sergei Manakov, EclipseBio
Tuesday, October 4, 2022
3:00 - 4:00 p.m.
Zoom
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RNA Collaborative Seminar, NUS-CSI Singapore RNA Biology Center | |
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Wednesday, October 5, 2022
10:00 - 11:00 a.m.
Zoom link
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Weird nuclear noncoding RNAs regulating DNA methylation, mRNA transcription, and DNA replication
Daniel Tenen
Mapping RNA structures in single cells
Yue WAN
Moderator: Polly Chen
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Novel Structure of a Type I Polyketide Synthase Reductive Cassette
Tyler McCullough, Janet Smith Lab
Friday, October 7, 2022
10:00 - 11:00 a.m.
LSI Library
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Midwest Oligonucleotide Therapeutics Symposium | | |
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The Midwest Symposium on Oligonucleotide Therapeutics is a grassroots meeting in Indianapolis supported by an Oligonucleotide Therapeutics Society (OTS) Local Delivery Grant.
October 8 – 9, 2022
Indianapolis, IN
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U-M RNA Innovation Seminar | | |
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Roadblocks on mRNAs? Gene Expression Regulation by Upstream Open Reading Frames in Plants
Polly Hsu, Michigan State University
Monday, October 10, 2022
4:00 - 5:00 p.m.
BSRB, ABC with zoom option
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25th anniversary screening of GATTACA with Panel Discussion | | |
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Co-sponsored by Neurology, Human Genetics, and the Center for RNA Biomedicine
Monday, October 10, 2022
6pm: Panel Discussion on Science and Ethics of GATTACA in 2022
7pm: Screening of GATTACA (run time 1h 46m)
Michigan Theatre (603 E Liberty St, Ann Arbor)
Please RSVP to sraymo@med.umich.edu
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U-M Biological Chemistry Seminar | | |
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Single-Molecule Cell Biology Reveals the Molecular Mechanisms of Genome Integrity Pathways in Cancer Cells-Department of Biological Chemistry Seminar Series
Jens Schmidt, Michigan State University
Tuesday, October 11, 2022.
12:00 - 1:00 p.m.
5330 Med Sci I
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U-M Microbiology and Immunology Seminar | | |
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mRNA 3’ processing in development and virus-host interactions
Yongsheng Shi, UC Irvine
Faculty Host: Katherine R. Spindler / Flyer in PDF
Thursday, October 13, 2022.
12:00 - 1:00 p.m.
M3330 Med Sci I
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RNA Society of North Carolina Symposium | | |
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The symposium will feature world-class speakers, talks from submitted abstracts, and many great opportunities for networking. Abstract deadlines are Sept 16th (to be considered for talks) and Sept 26th for posters.
October 13–14, 2022
Durham, NC
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The "structural" journey of a ribonucleoprotein complex: From molecules to droplets
Rishav Mitra, James Bardwell Lab
Friday, October 14, 2022
10:00 - 11:00 a.m.
LSI Library
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Rustbelt RNA Meeting 2022 | | |
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October 14–15, 2022
Cleveland OH
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Harvard Initiative for RNA Medicine | | |
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Enhancing miRNA therapeutics through vehicle-free delivery and full chemical modification
Andrea Kasinski, Purdue University
Tuesday, October 18, 2022
3:00 - 4:00 p.m.
Zoom
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Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Magnuson, B., Bedi, K., Narayanan, I. V., Bartkowiak, B., Blinkiewicz, H., Paulsen, M. T., Greenleaf, A., & Ljungman, M. (2022). CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. iScience, 25(9), 105030. doi.org/10.1016/j.isci.2022.105030 | |
McLean, E. K., Nye, T. M., Lowder, F. C., & Simmons, L. A. (2022). The Impact of RNA-DNA Hybrids on Genome Integrity in Bacteria. Annual review of microbiology, 76, 461–480. doi.org/10.1146/annurev-micro-102521-014450 | |
Pham, V. V., Gao, M., Meagher, J. L., Smith, J. L., & D'Souza, V. M. (2022). A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA. Communications biology, 5(1), 819. pubmed.ncbi.nlm.nih.gov/35970937 | |
Liu, Y., Munsayac, A., Hall, I., & Keane, S. C. (2022). Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA. Journal of molecular biology, 167688. Advance online publication. doi.org/10.1016/j.jmb.2022.167688 | | | | | |
