The RNA Transcript, October 5, 2020
TODAY, Monday, October 5, 4:00–5:00 pm


UM RNA Innovation Seminar Series

“Defining functional hubs in RNA-protein interaction networks”
Chase Weidmann, Ph.D., Washington University School of Medicine in St. Louis

Keywords: mRNA regulation, noncoding RNA, RNA Structure, RNP granules
RNA Translated, our annual magazine and brief report is out!

We are pleased to share with you RNA Translated, the Center for RNA Biomedicine's annual magazine and brief report.

RNA Translated's main focus is on "2020, the year of the RNA viruses," with representative contributions from 10 RNA faculty members. We also feature our two Research Cores and broadly report on the Center's activity with a few highlights. With this publication, we aim to showcase the outstanding achievements and deep impact of the scientific collaborations emerging from the U-M RNA research community.

Special thanks to our all contributors.

We hope you enjoy the read!


Congratulations, Peter Todd, M.D., Ph.D., member of our Executive Committee!

Dr. Todd will serve as co-director of a Fragile X Center without walls with investigators at Michigan, Baylor College of Medicine, and Emory University. This Fragile X Center is one of three recently funded by National Institutes of Health (NIH). Fragile X syndrome is the most common inherited form of intellectual and developmental disability (IDD), and the repeat that causes Fragile X Syndrome can also result in neurodegeneration and premature ovarian failure. The center will receive $9 million over the next 5 years. See Dr. Todd's "featured scientist" profile.
 
Monday, October 5, 4:00–5:00 pm | U-M Center for RNA Biomedicine,
UM RNA Innovation Seminar Series

Chase Weidmann, Ph.D., Washington University School of Medicine in St. Louis
“Defining functional hubs in RNA-protein interaction networks”
Wednesday, October 7, 4:00–5:00 pm EDT | RNA Collaborative Seminar Series, hosted by The RNA Institute, The University at Albany

Joseph Wade, Ph.D. “Pervasive translation in Mycobacterium tuberculosis” 
Scott Tenenbaum, Ph.D., “sxRNA: The Engineering of trans-Acting 3-Way Junctions for Function” 
Moderator: Thomas Begely, Ph.D. 
Wednesday and Thursday, October 7–8 | EMBL Symposium
Thursday, October 8, 4:00–5:00 pm | U-M Center for RNA Biomedicine
UM RNA Student and Postdoc Council - Journal Club

In preparation for RNA Innovation Seminar of Oct 19, 4:00–5:00, (seminar registration required) with Gene Yeo, Ph.D., Professor, Dept of Cellular and Molecular Medicine, UCSD, Co-Director, UCSD Bioinformatics and Systems Biology Graduate 
"Systematic discovery of molecular and cellular functions of RNA binding proteins"
Monday, October 19, 4:00–5:00 pm | U-M Center for RNA Biomedicine
UM RNA Innovation Seminar Series

Gene Yeo, Ph.D., Professor, Dept of Cellular and Molecular Medicine, UCSD
"Systematic discovery of molecular and cellular functions of RNA binding proteins"

Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below are recent highlights.
Translational control in aging and neurodegeneration
Geena Skariah, Peter K. Todd, 20 September 2020, Wires RNA Wiley, https://doi.org/10.1002/wrna.1628

These new findings point to nodes in posttranscriptional gene regulation that both contribute to aging and offer targets for therapy.
Transcriptome analysis of primary podocytes reveals novel calcium regulated regulatory networks

Comparison of the ex vivo transcriptional response from the primary podocyte culture with glomerular transcripts across a wide spectrum of CKD disease confirmed co‐regulation of transcript sets, establishing the disease relevance of the model system. Our findings demonstrate novel [Ca2+] regulated gene networks in podocytes deepening our understanding of podocyte biology and disease.
Diversity, Equity and Inclusion
Join the 900+ scholars from more than 200 iNstitutions across the world to:

The National Center for Institutional Diversity (NCID) invites all tenured, tenure-track, clinical and research faculty (including lecturers), research staff, and postdoctoral fellows dedicated to diversity scholarship to become a member of the Diversity Scholars Network (DSN)!

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