Developing & advancing new HP MRI technology to better
detect, understand, and treat human diseases worldwide

2024 Highlights & 2025 Workshop Announcement

As we welcome the fall season, we are reflecting on 2024 and some of the great advances in HP C-13 MRI Technology accomplished over the past year. In this newsletter we highlight recent seminar presentations and present recent publication releases by the HMTRC in developing and advancing HP C-13 MR technology to better identify and understand human diseases and ultimately to improve patient care.


Also, announcing our 2025 HMTRC Workshop dates! See below for details! Registration and event details to be released Winter 2024.


Wishing you all a great fall season,

The HMTRC team & Collaborators



Save-the-Date: HMTRC Workshop for

Hyperpolarized Carbon-13 MRI Technology Development

April 3rd-4th 2025, Pre-meeting Events April 2nd Afternoon

The April 2025 Hyperpolarized Carbon-13 MRI Technology Development Workshop includes lectures, hands-on training and discussions on dissolution DNP methodology, polarizer instrumentation, MR Sequence and Acquisitions, Pre-clinical HP Chemistry Preps, Human HP Investigational Dose Formulation & Production, Clinical Translation Methods, Clinical Trial Research, and Analysis & Display Software.

Visit Events on our Website for Updates

The HMTRC Website. What's New?

Recently Released: HP C-13 MRI Seminar Presentations

View All Video Talks & Tutorials
HMTRC Recent Research Publications
Recent journal articles supported by the center
to inspire & drive your basic and clinical research

Dual hyperpolarized [1-13C]pyruvate and [13C]urea magnetic resonance imaging of prostate cancer

de Kouchkovsky I, Nguyen H, Chen HY, Liu X, Qin H, Stoher BA, Delos Santos R, Ohliger MA,Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Gebrezgiabhier D, Cooperberg M, Vigneron DB, Kurhanewicz J, Aggarwal R


JMRO

October 2024

A pharmacokinetic model for hyperpolarized 13C-pyruvate MRI when using metabolite-specific bSSFP sequence

Sahin S, Garnæs MF, Bennett A, Dwork N, Tang S, Liu X, Vaidya M, Wang ZJ, Larson PEZ  


Magn Reson Med

October 2024

Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumors

Mu C, Liu X, Riselli A, Slater J, Escobar E, Dang D, Drapeau S, Delos Santos R, Andosca S, Nguyen H, Larson PEZ, Bok R, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR


STAR Protoc

June 2024

Detection of early-stage NASH using non-invasive hyperpolarized 13C metabolic imaging

von Morze C, Blazey T, Shaw A, Spees WM, Shoghi KI, Ohliger MA


Sci Rep

June 2024

Brain metabolism after therapeutic hypothermia for murine hypoxia-ischemia using hyperpolarized [1-13C] pyruvate magnetic resonance spectroscopy. 

Liu X, Manninen T, Capper AM, Jiang X, Ellison J, Kim Y, Gurler G, Xu D, Ferriero DM


NMR Biomed

June 2024

Visit HMTRC Research Publications

Call for Seminar Presenters

We are currently looking for presenters for our International HP C-13 MRI Seminar for November & December 2024. Present new findings, publications, or other work in preclinical and human research. Presentations are 25 minutes with a 5-minute Q&A. Email us at hyperpolarizedmri@ucsf.edu.

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The Hyperpolarized MRI Technology Resource Center (HMTRC) is supported by the National Institute of Biomedical Imaging and Bioengineering
(NIH P41EB013598) and focuses on the development and dissemination of new advances in dissolution DNP techniques and instrumentation, specialized data acquisition methodology, and analysis software for biomedical research. 
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