Tania Jain, MBBS

Johns Hopkins School of Medicine

Baltimore, MD

Could her project using the molecule SLAMF7 be the breakthrough that transforms patient outcomes? Discover how Jain's relentless quest for answers is bringing new hope to those living with MF. Read more>

MPN Cover Story in Blood 

A research cover story is always exciting for the myeloproliferative neoplasm (MPN) community. The first June issue of the journal Blood features a colorful bone marrow photomicrograph on the cover. Inside is a study plus accompanying commentary that suggests NF-kB as a new, potentially important MPN treatment target. In vivo ablation of NF-κB cascade effectors alleviates disease burden in myeloproliferative neoplasms is authored by Stephen T. Oh, et al.

“The study takes a significant step forward in establishing NF-ĸB as a bona fide target in MPN, to not only address chronic inflammation, but also ameliorate clonal expansion and fibrosis,” writes Angela Fleischman, MD, PhD about the featured article. Both Drs. Oh and Fleischman are recipients of multiple MPN Challenge awards in support of their work in related areas.

Living with MPNs: Patient Stories

Ben Hohenbrink: "How do you even spell ET?"

Ben’s primary care physician sent him to an oncologist at his local hospital when his platelets hit just under one million. Later they peaked at 1.3 million. Still, nobody seemed too alarmed. Read more>

MPN News & Resources

Introducing MPN Pathways:

Empowered Voices in MPN Research

Become a certified MPN Research Advocate!

Join our webinar program, MPN Pathways: Empowered Voices in Research, to explore MPN disease education, drug development, clinical trials, and how patients and caregivers can contribute their insights to MPN research. 

Stay tuned for our first program session, "MPN Research Foundation and Myeloproliferative Neoplasm (MPN) 101," designed to provide essential knowledge on MPN diseases, treatments, and advocacy. Connect with experts and like-minded individuals dedicated to advancing MPN research. 

Keep an eye out for registration information over the next couple of weeks. 

What we know about MPNs in adolescents

and young adults 

Historically, MPNs are diagnosed in adults 60 years or older. In recent years, however, there has been recognition of essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) in adolescents and young adults, often referred to as AYAs.

A recent article in British Journal of Haematology offers a comprehensive review of the literature about AYAs, authored by a number of international leaders in MPNs. 

While reports vary regarding the prevalence of AYA MPNs, the range is approximately 10%-20% of MPN cases that may be attributable to people in this age group (15-39). Out of the classical MPNs, ET is most common, followed by PV, then primary myelofibrosis. Read more>

Research interview opportunity for myelofibrosis

(MF) patients 

In partnership with Pinpoint Patient Recruiting, we are raising awareness about an opportunity for US-based adults diagnosed with myelofibrosis more than 6 months ago. Participation involves a 75-minute online interview. The information gathered will help researchers better understand the experiences of individuals living with myelofibrosis and how they make decisions about their treatments. There is a $125 compensation “thank you” along with the assurance that all information and responses will remain confidential. To find out more and to see if you qualify, visit the pinpoint website here

or contact Julie Knell at julie@pinpointpatientrecruiting.com.    

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MPN RESEARCH FOUNDATION

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Clinical Trial Highlights

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MPN Research Foundation

PO Box 2690 | Carol Stream, IL 60132

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