Minneapolis Heart Institute Foundation

Structural Research / Valve Science Center Update

Q1 2025

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Celebrating Our Impact in 2024

Recognized for scientific excellence by the Cardiac Research Foundation (CRF)
Authored 116 publications
Presented 120+ talks around the world

Study Spotlight: Evolut EXPAND II

Description

Study randomizing participants with heart failure and moderate aortic stenosis to TAVR with the Evolut PRO+ or Evolut FX System, or GDMT alone.

Contact

Amanda Folberg

Amanda.Folberg@allina.com

Principal Investigator:

Dr. Paul Sorajja

Enrolling Clinical Studies

Aortic

Study

Device

Evolut EXPAND ll

Medtronic

TAVR - Mod. Aortic Stenosis

Dr. Paul Sorajja

ALIGN AR

JenaValve

TAVR – Aortic Regurgitation

Dr. Paul Sorajja

Mitral

AltaValve Pivotal 4C Medical Technologies	TMV Replacement	Dr. Paul Sorajja
REPAIR MR Abbott Medical Devices	MitraClip vs. Surgical Repair	Dr. Paul Sorajja
SUMMIT Abbott Medical Devices	TMV Replacement – MAC arm only	Dr. Paul Sorajja
APOLLO Medtronic	TMV Replacement	Dr. Paul Sorajja

Tricuspid

VISTA-US

Vdyne, Inc

TTV Replacement

Dr. Paul Sorajja

Intrepid TTVR EFS

Medtronic

TTV Replacement

Dr. Vinnie Bapat

TANDEM II

CroiValve Limited

DUO Transcatheter Tricuspid Coaptation Valve System

Dr. Paul Sorajja

Left Atrial Appendage

LeAPPS

AtriCure

LAA Exclusion Device (Clip)

Dr. Vinnie Bapat

Other

PROTECT H2H

Emboline

Emboliner vs. Sentinel – Cerebral Embolic Protection during TAVR

Dr. Paul Sorajja

PARADIGM

Abbott

Amplatzer Valvular Plug III (AVP III) for significant PVLs following surgical aortic or mitral valve replacement

Dr. Paul Sorajja

Pipeline Studies

TRICAV ll

P+F Products

TricValve Bicaval Valve System to treat tricuspid regurgitation and caval reflux

Dr. Paul Sorajja

LAA=Left Atrial Appendage; MAC=Mitral Annular Calcification; PI=Principal Investigator; PVL=Paravalvular Leak; TAVR = Transcatheter Aortic Valve Replacement; TMV = Transcatheter Mitral Valve; TTV = Transcatheter Tricuspid Valve

For more information, please contact Nikki Degeneffe at Nicole.Degeneffe@allina.com; Ph: 612-863-6286