February 5, 2014   Vol. V, Issue 6
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Severe Kingella kingae Osteoarticular infections in children.

While K. kingae osteoarticular infections in children are frequently clinically mild, a retrospective study of a small series of 10 children (mean age 21 months) who presented with severe osteoarticular infections caused by this organism reminds us that severe bone disease can present without fever or elevated C-reactive protein levels. Delay in diagnosis may result in bony lytic lesions and growth cartilage damage.

Pediatric Infectious Disease Journal 

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Probiotic effects on late-set sepsis in very preterm infants

While probiotic use appears to reduce mortality and necrotizing enterocolitis (NEC) in preterm infants, their effect on late-onset sepsis is unclear.

A randomized control study of a probiotic combination or a placebo given daily (in 1099 mostly breast milk fed very preterm infants), examined the differences found , with & without their use, for late-onset sepsis, NEC and mortality.

Probiotic administration appears to reduce the risk of NEC in preterm infants - it does not appear to reduce late-onset sepsis or mortality.



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Children's sleep duration, food intake, weight and Leptin


Increased sleep duration in school-aged children appears to result in less food intake, lower weight and lower fasting Leptin levels. Decreased sleep times may be one factor contributing to obesity in children.



Late clinical presentation of congenital adrenal hyperplasia (CAH) in older children.


30 children annually (between 1-15 years of age: median 5.8 years) in the UK present for the first time with CAH: Boys presenting in approximately equal numbers to girls. 86% have 21-hydroxylase deficiency and the diagnosis is usually precipitated by pubertal maturation (66%), genital virilisation or the presence of an affected sibling. 57% have an advanced bone age and 30% are obese. Newborn screening avoids the potential of serious clinical manifestation presenting in older children.


Video Feature  
Congenital Adrenal Hyperplasia (CAH)
Congenital Adrenal Hyperplasia (CAH)
via YouTube

Using a "safe taxi service" to transport newborn babies home from the hospital


In many communities parents may not be extensively exposed to television, the internet and/or main stream printed media. They may never have used a car safety seat (CSS) previously, and may be less aware or unable to have a CSS available to them in which to take their newborn babies home.

An interesting study from Israel documents the use of a "safe taxi service" to transport newborn babies home. Drivers are trained to install a hospital lent CSS. At follow-up 4-8 weeks later 86% of parents report using a CSS while traveling in all vehicles (excluding buses), demonstrating the value of this process to increasing car safety awareness.


Acta Paediatrica 

Telemedicine consultations reduce medication errors in rural emergency departments (ED).


A retrospective chart review of seriously ill or injured children

presenting to 8 rural EDs indicates that consultations with a Pediatric critical care physician form an academic hospital significantly reduces the risk of physician-related ED medication errors.



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