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Impact of stretching exercises vs. bedding pillows on positional head deformities in young infants
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Positional head deformities in early infancy frequently cause concern, particularly since babies have been placed on their backs to sleep. Primary prevention includes varying the babies' head position during sleep, while physical therapy (particularly neck muscle stretching exercises) positioning devices and bedding pillows (to remove pressure on the occiput during sleep) may be utilized at 5 months of age as secondary therapies.
50 children, aged 5 moths or younger with plagiocephaly, brachycephaly or a combination, were randomly assigned to 2 treatment arms; bedding pillow alone or with stretching exercising for 6 weeks. Measurements of the cranial vault were taken and asymmetry analyzed.
Bedding pillows and stretching exercising both result in improvements in positional cranial deformation.
Journal of Pediatrics
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Toll-like receptors (TLR) in neonatal sepsis
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Toll-like receptors are a class of protein receptors, expressed by macrophages (and other cells) that recognize broadly shared pathogen associated wall molecular patterns, which activate host cellular immune responses. TLR 2 and 4 are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.
TLR's play an important role in initiating immune responses and their potential modulation during neonatal sepsis may play an important role in reducing neonatal morbidity/mortality.
Acta Paediatrica
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