Weekly Updates in Pediatrics         October 3, 2012 

EDITOR:  Jack Wolfsdorf, MD, FAAP 


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Bocavirus in acute gastroenteritis (AGE) in children

Human bocavirus (HBoV) (hosts: bovine and ca

nine) is a parvovirus identified in 2005, which appears to be the fourth most common virus found causing lower respiratory infection in humans. Recently, it has been found to be associated with AGE in children.

HBoV of any type is found in 9.7% of children with AGE (and 5.4% of controls), but in only 1.8% of cases as a single infection. HBoV2 is the most common (50%) single type identified. HBoVs are rarely found alone in children with AGE.


Source: Acta Paediatrica

Risk factors for sedation in infants undergoing magnetic resonance imaging (MRI) in the Emergency Department (ED)

Chloral hydrate is frequently used to sedate children undergoing MRI. Success rates between 80-100% have been reported. The success rate however, may vary with age, weight and underlying disease.


It appears that successful chloral hydrate sedation most commonly occurs in infants younger than 18 mths. of age and who weigh <11.4kg. Adverse events (10%) associated with sedation increase above 18 mths. of age, and older infants (24 mths.) with neurological disease.


Source: The American Jounal of Emergency Medicine

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Viruses in bronchiolitis


While we recognize the importance of Respiratory Syncitial Virus (RSV) in the etiology or bronchiolitis, human rhinovirus (HRV-the agent for the common cold) either alone or as a co-infector, frequently plays an important role in affecting severity of clinical respiratory disease and length of hospital stay (HRVs may be shed from the respiratory track for up to 4 weeks in the newborn).


Molecular biological advances will soon open the door to clinical correlation with not only RSV and HRV infections but also to information on parainfluenza, influenza, novelinfluenza A (H1N1) and human metapneumovirus and clinical role all these viruses play in the presentation of respiratory illness in young children.


Source: Archives of Pediatric & Adolescent Medicine

Video Feature



 Dr. MDK via YouTube 

Does Simultaneous bilingual upbringing aggravate children's language disorders?


56, 5-7 year old children with language problems who are brought up in a bilingual home environment were assessed for expressive language, comprehension, repetition and verbal memory and compared to a similar group raised in a monolingual home.


It appears the simultaneous bilingualism in a home does not aggravate specific language problems, but may result in slower vocabulary development.


Source:  Acta Paediatrica 

Ambulatory Health-Related Quality of Life (HRQL) in children with myelomeningocle (MMC)


The parents of 62 children (mean age 12.5 yrs.) with MMC completed a questionnaire (which was compared to a normal control group) and which examined general health-related quality of life issues of their children. Most (68%) MMC children were non-ambulatory, using wheelchairs to get around.


Parents of ALL MMC children perceived significantly poorer HRQL for their children; MMC children who could walk reported a better quality of life in the physical domain compared to those who couldn't.  


Source:  Acta Paediatrica  

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