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Prognosis of Liver disease associated with prolonged Parenteral nutrition (PN) |
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Intestinal associated liver disease (ILD) has been reported in 40% to 60% of children receiving PN. 87 infants receiving long term PN for at least 28 days were assessed and 33% of them diagnosed with ILD.
24-month follow up of patients receiving PN with associated ILD indicates that most can be managed medically and that the majority of them reverse their liver disease. Most subsequently can be fed enterally.
Source: Journal of Pediatric Surgery, February 2012 |
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Flumazenil induced seizures |
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Flumazenil is a benzodiazepine (BZ) antagonist frequently used as an antidote in the treatment of BZ overdose (it may also be effective in non-BZ sleep enhancing drug overdose). The most serious side effect of its usage is seizures.
A retrospective study of 83 children (3 mths - 12 years) given Flumazenil primarily for BZ poisoning found NO occurrence of Flumazenil associated seizures.
Source: Pediatric Emergency Care, May 2012 |
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"Distraction" as a technique to diminish pain |
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A study of a "distraction" technique (compared to a control group) using audiovisual (A/V) glasses, on pain perception was undertaken during administration of local anesthesia in 45 healthy, cooperative 5-7 year old children undergoing nerve block anesthesia.
Pain perception using A/V glasses is significantly reduced in children undergoing injection of local anesthesia.
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