April 5, 2017
The long-acting, nonhormonal contraceptive -- for men.
Rabbit reversal study published today
Sperm flow resumed after contraceptive was flushed out
After Vasalgel served as an effective contraceptive in a group of rabbits, researchers succeeded in restoring sperm flow by flushing the gel to clear it from the vas deferens. If you've been following Vasalgel updates, you heard a preview of these findings last year. The full results were published today in the journal Basic and Clinical Andrology .
 
The study followed the progress of seven rabbits that had received injections of Vasalgel, which blocked the release of their sperm for more than a year while causing no significant side effects; those effectiveness results were published last year. In this second part of the study, after the rabbits received injections to clear the Vasalgel, sperm flow was reestablished.

"The results of the Vasalgel reversibility study in rabbits indicate the implant could be removed, resulting in a quick return of sperm flow," said lead author Donald Waller, Ph.D. The results mark an important milestone in the development of Vasalgel: they provide important proof of concept around restoration of sperm flow, and encourage further development work.

You can read the full study online here; Parsemus Foundation policy is to only publish in open-access journals so the results are available free to all. Want a shorter version, with the results in context? Here's the press release.
Reversal in rabbits: what does it mean for men?
Vasalgel gains momentum
Man Upward Rocket
The rabbit results published today were the first evidence supporting development of Vasalgel as a safe, effective, and reversible male contraceptive. Sperm counts and motility were restored, with future studies planned to improve consistency of the flushing technique. The findings provide important momentum for continued development of Vasalgel.

When we surveyed Vasalgel followers a year ago, many respondents said they see Vasalgel as being better than vasectomy due to potential for procedural simplicity and reduced side effects. But most respondents regarded reversibility as important, and 18% called it "essential," which makes these results especially encouraging.

Meanwhile Vasalgel continues to attract interest from the public and the media; the publication in February of a study showing that Vasalgel was effective in rhesus monkeys got international media coverage. Today's publication builds on that momentum, and should increase our ability to raise the funds to pay for the upcoming trials in men (see story below).
Start a Vasalgel fundraiser
New Facebook tool makes it easy
Helping Hands
Vasalgel fans have often asked how they can help bring Vasalgel to market. When we've requested donations, many of you have given generously. While the cost of clinical trials for Vasalgel requires support from mission-oriented social investors, individual donations continue to be an important part of the overall funding mix.

Fortunately, Facebook recently rolled out a tool that makes it easy for individuals to raise funds for nonprofit organizations from their Facebook friends. If you're on Facebook, please consider starting a fundraiser for Parsemus Foundation, the nonprofit organization that's developing Vasalgel.

This link will get you started. Give your fundraiser a title, enter a description of why people should donate, and set a goal amount for the fundraiser. You have the option to set an "end date" too, but we recommend you select "no end date" for now. Thank you!
We're working hard and are grateful for your support!

Sincerely,
the Vasalgelâ„¢ team

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