October 2019

WCRG Matters
A newsletter to keep members and partners informed.
Caesar's Windsor Supports WCRG Again!
WCRG is thankful once again for the support of Caesars Windsor Concerts for A Cure campaign! $1 from every ticket sold in October and November will go towards purchasing advanced imaging equipment to keep driving discoveries forward.  A list of events included in the Concerts  for A Cure Series can be found on the  Caesars Windsor website .
Play For A Cure Exceeds Expectations!
Play for A Cure 2019 was a huge success exceeding all expectations and raising almost $285,000! Part of the money raised will go to the new Cancer Research Incentive Fund and Cancer Care Grants. This announcement kicks off plans for the next Play for A Cure tournament in 2020, scheduled to take place  March 26-27 at Caesars Windsor and the Vollmer Complex in LaSalle. A big thank you to Jeff Casey, Chair of Play for A Cure, and his entire team for their continued commitment to WCRG and cancer research in Windsor-Essex! More information about the event can be found on the Play for a Cure website.

Think Tank Series - Mark your Calendars for 2020
On Friday October 18th, WE-SPARK Health Institute hosted the last health research Think Tank of 2019. The event featured three presenters focused on collaborative teams in children's mental health, unique opportunities in 18F Generation PET imaging, and smart mobility for an aging population.

Fast Facts about this Think Tank: There were 43 participants representing 10 organizations and 20 disciplines. Participants, on average, rated the event 4.8 out of 5.
There will be six opportunities in 2020 to participate, collaborate, and connect! Mark your calendars for the next Think Tank on January 24th, 2020. 
WCRG Researcher Snapdshot
WCRG continues to partner with snapd Windsor to highlight our WCRG cancer researchers through a feature called "WCRG Researcher Snapdshot". Interviews can be found in the print edition of snapd Windsor and on the WCRG website. The goal of these "Snapdshots" is to raise awareness about the cancer research conducted in Windsor-Essex and stimulate new research collaborations. Be sure to pick up the latest edition of snapd Windsor! See the latest researchers featured  on the WCRG website.
Connecting with the Community
We have had a busy Fall! A new semester has started for our students and the CURE Team has been actively engaging the community at several events including:
  • Open Streets Windsor
  • Schulich Medical Student Open House
  • Multiple Myeloma Walk
  • WRH Cancer Education Day
  • Run for a Cure
For pictures from the events check out Flickr 
Meet Our WCRG Project Leaders
Ryan Palazzolo, Alex Rodzinka, Kaila Wilson 
WCRG has 3 new Project Leaders: Ryan, Alex, and Kaila! All are CURE graduates and will be important in moving WCRG priorities ahead in 2020. Each will gain hands-on experience in cancer education - mentoring students and organizing community engagement events, all while learning the inner workings of WCRG. We look forward to the upcoming year and the energy they bring to moving cancer research forward.
Member Highlights
Letting us know about  the accomplishments of you and your colleagues allows us to  celebrate the great work being done in our region and further  build collaborations. Here are just a few of your latest successes.

John Trant (University of Windsor, Department of Chemistry and Biochemistry) ($100,000). Ministry of Economic Development, Job Creation, and Trade's Early Researcher Award program. The University of Windsor will contribute an additional $50,000 toward the award.
Funded Projects/Clinical Trials 
REC.4 (PROSPER RCC): A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Localized Renal Cell Carcinoma Undergoing Nephrectomy; ID: NCT03055013 
Dora Cavallo-Medved and Lisa Porter. University of Windsor U ndergraduate Research Experience Grant. Investigating the Impact of Experiential Learning in Undergraduate Cancer Research and Education.
Bakht MK, Stringer KF, Lovnicki JM, Pillon A, Shahbazi-Raz F, Hayward JJ, Oh S, Trant JF, Cheon G, Kwak C, Jeong C, Kang K, Wang Y, Dong X, Porter LA. (2019).  Loss of PSMA during neuroendocrine differentiation of prostate cancer is associated with elevation of metabotropic glutamate receptors as an alternative diagnostic target. Eur J Nucl Med Mol Imaging,  46 (Suppl 1): S695
Lepore R, Kryshtafovych A, Alahuhta M, Veraszto HA, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Grusaran M, Gutche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Mischalska K, Mir-Sanchis I, Mitra A, Moult J, Phillips GN Jr, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T. (2019). Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins. doi: 10.1002/prot.25805
Bozelli JC Jr, Yune J, Hou YH, Chatha P, Fernandes A, Cao Z, Tong Y, Epand RM. 2019. Regulation of DGKε Activity and Substrate Acyl Chain Specificity by Negatively Charged Phospholipids. Biophys J S0006-3495(19)30782-9. doi: 10.1016/j.bpj.2019.09.008
Caroline Hamm (Medical Oncology, Windsor Regional Cancer Program). Patient-Centred Clinical Trials Access: The Clinical Trials Navigator. Canadian Cancer Research Conference (CCRC), Ottawa, Ontario: November 3 -5, 2019 
Ming Pan (Radiation Oncology, Windsor Regional Cancer Program). Can We Use Hounsfield Unit Ranges as Surrogates for Functional Lung Avoidance in 4-Dimensional Comterized Tomography Simulation Datasets: A Pilot Study. Canadian Association for Radiation Oncology, Halifax, Nova Scotia: October 2-5, 2019.
Members in the News
A recent edition of BioSpace highlights the importance of a local initiative spearheaded by Dr. Caroline Hamm. The Clinical Trial Navigator pilot program, through the  Canadian Cancer Clinical Trial Network (3CTN), allows patients to connect with a navigator to  help them find potential clinical trials.  
Be sure to submit any news items as they happen and we will include them. Pictures and links to details are welcome!