March 2024 Newsletter

This annual San Francisco Business Times event was another huge success.

Wareham has proudly sponsored the annual Women Who Lead in Life Sciences event since its inception, and have been awed by our tenant leaders and all who have shared the stage over the years. Karen Walker, Chief Technology Officer at Kyverna Therapeutics (fourth from left on panel), shared her remarkable experience and strength. We thank her and the Kyverna team for joining us.

We thank San Francisco Business Times biotech reporter Ron Leuty for leading another great panel. The Wareham team especially thanks publisher Mary Huss for her steadfast, creative, impactful leadership over the years at the San Francisco Business Times. This event is only one of the many gifts she has given the Bay Area over the years. Thank you, Mary!

In addition, we were delighted to read inspiring reports in the accompanying focus section of the March 15 issue about:

• Nobel winner Jennifer Doudna, (a guiding influence for Rachel Haurwitz and Caribou Biosciences) and the HS Chau Women in Enterprising Science Program within the Innovative Genomics Institute founded by Dr. Doudna.
• Heather Turner, CEO, Carmot Therapeutics, was featured in the Women Breaking Through article and whose team has commenced the important next-step Phase 2 clinical trial of its CT-868 in adult participants with type 1 diabetes.

Finally, please take a look at Wareham's ad HERE also in that issue in which we note many of the Women Who Lead in Life Sciences as tenants at our research campuses and celebrate all the women in these companies.

Many thanks to Yasmina Abdiche and Bob Chen of OmniAb

for great presentations at the hybrid

EmeryStation Research Campus Speaker Series.

This noon speaker series attracted 75 people who attended via zoom or who came in person to network with colleagues and enjoy a great free lunch!

Wareham's long-term relationships with our tenants and the greater Bay Area research community make our networking events popular. Besides our two monthly Wareham hybrid luncheon speaker series, we have great venues at our EmeryStation Research Campus and our Aquatic Park Research Campus to host daytime or after-work panel programs or other networking events.

Please contact Judy Wetterer to discuss your ideas for a speaker series lunch* or for other networking opportunities. We look forward to helping you make those ideas happen and to helping you and your team meet your goals.



*Typically, the EmeryStation Research Campus speaker series is held on the first Thursday of every month. The Aquatic Park Research Campus speaker series, co-hosted with Lawrence Berkeley National Laboratory, is held on the third Thursday of each month. The presentations start promptly at noon with free bag lunches provided. Tenants from our research campuses and greater research community are all invited to attend both events. The speaker series are hybrid in-person and Zoom gatherings, unless you prefer an in-person event only.

Other highlights to share as well.

Joint BioEnergy Institute announced that Jay Keasling, PhD, CEO and Director of New Pathway Development, is the recipient of two prestigious awards:



• Humboldt Research Award for his achievements and expertise in biochemistry, genetics of microorganisms, and applied microbiology.
• Bakar Prize to engineer bacteria to produce probiotics to treat skin diseases caused by the bacteria Staphylococcus aureus.

4DMT Molecular Therapeutics

• 4DMT presented positive interim data from Randomized Phase 2 PRISM Clinical Trial of Intravitreal 4D-150 demonstrating favorable tolerability and clinical activity in Wet AMD.
• In interview with Nature Portfolio, CEO David Kirn, MD, expanded on 4DMT's use of directed evolution to significantly improve genetic delivery to target cells and tissues, transforming treatments for patients with severe common diseases.
• 4DMT announced pricing of upsized public offering of common stock (Nasdaq: FDMT).

ABPDU (Advanced Biofuels and Bioproducts Process Development Unit) announced that ABPDU and its partners had developed bio-derived ionic liquids derived from lignin, a natural polymer found in plant cell walls. The research was supported by an award from the U.S. Dept. of Energy's Office of Technology Transitions' Technology Commercialization Fund.

Activate announced in its impact stats for 2023 that last year alone, Activate Fellows raised $263M in follow-on funding, created over 600 jobs, secured 300 corporate partnerships, and won nearly 80 awards. Activate received over 800 fellowship applicants and welcome their most diverse cohort yet, with 37% women and $43 founders of color.

Kyverna Therapeutics

• Kyverna and Stanford University agree to evaluate KYV-101 in patients with non-relapsing and progressive forms of Multiple Sclerosis.
• Kyverna announced closing of its initial public offering and full exercise of underwriters' option to purchase additional shares (Nasdaq: KYTX).

Metagenomi announced the closing of its initial public offering (Nasdaq: MGX).

Nutcracker Therapeutics announced it will present data on mRNA Drug Candidate and Immunomodulatory Cytokine at the 2024 American Association for Cancer Research Annual Meeting.

Pivot Bio was named a Fast Company Most Innovative Company for their work to harness the power of nature to solve one of the biggest challenges facing modern agriculture.

Sangamo Therapeutics

• Announced U.S. FDA Alignment on Abbreviated Pathway to Potential Approval and EMA Prime Eligibility for ST-920 in Fabry Disease.
• Announced their novel neurotropic AAV capsid that demonstrated industry-leading blood brain penetration and brain transduction in non-human primates following intravenous administration.

2024 East Bay EDA Innovations Awards

We look forward to celebrating with our tenants 4D Molecular Therapeutics and Climax Foods, who are both award finalists in different categories. It's always great to learn about and celebrate the incredible innovation in the East Bay.

Please continue to support these popular and loved restaurants serving our campuses and cities.

Check out their websites, call, or order from your favorite restaurant app. Many of them cater your lunches and meetings as well.

warehamdevelopment.com

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for noble and Nobel scientists.

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