“Bad fat” suppresses killer T cells from attacking cancer |
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In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized “killer” T cells. Salk researchers led by Professor Susan Kaech have found that the environment inside tumors (the tumor microenvironment) contains an abundance of oxidized fat molecules, which, when ingested by the killer T cells, suppresses their ability to kill cancer cells. The work suggests new pathways for safeguarding the immune system’s ability to fight cancer and could lead to the development of novel immunotherapies.
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Research advances one step closer to stem cell therapy for type 1 diabetes |
Type 1 diabetes, which arises when the pancreas doesn’t create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure and is difficult for most patients to manage. Salk scientists led by Professor Juan Carlos Izpisua Belmonte published a promising approach in the journal Nature Communications for treating it: using stem cells to create insulin-producing cells (called beta cells) that could replace nonfunctional pancreatic cells.
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Inhibitory neurons target the weakest-responding neurons in the brain to facilitate transmission of signals |
A new study led by Professor Tatyana Sharpee and published in the journal Cell Reports shows that inhibitory neurons do more than just inhibit neuron activity like an off-switch; they actually increase the amount of information transmitted through the nervous system when it needs to be flexible. The work could help scientists better understand and treat conditions such as anxiety and attention deficit disorders.
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How plants quickly adapt to shifting environmental conditions
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A paper from the labs of Salk Professors and Howard Hughes Medical Institute Investigators Joanne Chory and Joseph Ecker offers a new understanding of how gene activity directs plant growth, and how quickly plants respond to their environment—with shifting light conditions triggering molecular changes in as little as five minutes. The findings may help farmers increase yield and safeguard world food production as climate change shrinks the planet’s arable land.
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Photo credit: Chan Yul Yoo, Meng Chen lab, UC Riverside
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“Witnesses are often wrong”: The case against eyewitness ID
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Neurons made from fibroblasts keep imprint of Alzheimer's, aging
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HPI’s suberin strategy mentioned in The Washington Post's climate solutions quiz
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The 10 most important health breakthroughs you missed during the pandemic
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Scientists discover how stem cells trigger muscle regeneration
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Late night cravings? Blame it on your hormones
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Panda lab's Postdoctoral Researcher Emily Manoogian gives a TEDxGateway talk on "Body Clocks and the Importance of Timing"
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Salk Institute receives Charity Navigator’s highest rating for tenth consecutive time |
For the tenth consecutive time, the Salk Institute has earned the highest ranking—4 out of 4 stars—from Charity Navigator, America’s largest independent charity and nonprofit evaluator. Only three percent of the roughly 10,000 nonprofits evaluated have achieved this recognition ten consecutive times. The coveted ranking indicates the Salk Institute has demonstrated strong financial health and commitment to accountability and transparency, outperforming most other charities in America in regard to executing best fiscal practices and carrying out its mission in a financially efficient way. |
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NOMIS Center for Immunobiology and Microbial Pathogenesis has announced its 2021 NOMIS Fellows |
Congratulations to Dan Chen, Lidia Jiménez, Andre Mu and Jan Pencik. Click on the button below to learn more about their research.
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Postdoc receives Pathway to Independence Award |
Congratulations to Laura Newman, a postdoctoral fellow in the Shadel lab, for being awarded an NIH Pathway to Independence award for a 5-year study of the role of mitochondrial/ER contacts in the regulation of mtDNA release from mitochondria, innate immune signaling, and responses to viral infection. |
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Salk mourns postdoc Swati Tyagi |
The Salk Institute mourns the loss of Swati Tyagi, PhD, a postdoctoral researcher in the Hetzer lab, who was struck by a person driving a car while cycling on June 23. Swati is survived by her husband, Ashim Rai, and her 11-month-old son, Miransh. Tyagi joined Salk in 2016 as a research associate and since then, received numerous recognitions including the 2017 Salk Women & Science Special Award.
A GoFundMe page has been created to provide interested individuals with a way to help Tyagi’s family with a financial gift of support. (Please note that this donation page is organized by Tyagi’s colleagues at the Salk Institute, but it is not a Salk Institute program. Donations made are not tax-deductible.)
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In memoriam: Salk mourns a longtime donor |
The leadership, faculty, and staff of the Salk Institute for Biological Studies mourn the passing of great friend and generous philanthropist Edward Streim. Ed was a man of charm, wit and intellectual curiosity. Salk is forever grateful for his many contributions to the advancement of science and innovation, which made a significant impact on the groundbreaking research for which the Institute is renowned. Salk extends its deepest sympathy to Ed's wife, Lynn, and to the entire family. |
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Sponsorships are now available to the 25th annual Symphony at Salk. The event will feature a spectacular evening of music featuring a performance by the legendary Josh Groban and the talented San Diego Symphony. Experience warm camaraderie, gourmet food and drink, a breathtaking sunset and refreshing ocean breezes, all against the backdrop of one of the world’s most striking architectural masterpieces. Symphony at Salk is the cultural event of the summer and sponsoring the event is currently the only way to take part in this extraordinary experience. Individual tickets are not available at this time due to current capacity restrictions.
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Enjoy Salk science on your devices |
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Looking for a unique background image for your computer, Zoom meeting, iPad or phone?
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