August 13, 2019
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Wound Infection and Biofilm Treatment

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In The News
Cellular Engines of Wound Repair Have Distinct Roles
Following tissue injury, fibroblast cells activate, divide and play key roles in both tissue repair and pathological scarring—fibrosis—that can drive organ failure. Vanderbilt investigators have now discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury. "Our work offers a new perspective over the currently held thinking that fibroblasts are a single population of cells working in the same manner to coordinate wound repair," said Pampee Young, MD, Ph.D., adjunct professor of Pathology, Microbiology and Immunology.

 Discordant Themes Exist in Skin Cancer Assessment Outcomes Among Physicians, Patients 
Areas of disagreement between patients and physicians on skin cancer-related outcomes include patient fear of the unknown, recurrence and empowering patients to make treatment choices, according to researchers in Dermatologic Surgery. “The shift from a physician/disease-specific point of view to a patient-oriented one has created a new set of qualitative outcomes,” Anthony M. Rossi, MD, of the dermatology service at Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College in New York, and colleagues wrote.
Researchers Identify Barriers to Fungal Infection Diagnosis
There are several barriers that prevent the consistent use of fungal diagnostic preparations to correctly identify cutaneous fungal infections, according to a survey from a team at the George Washington University (GW). The study is published in the Journal of Drugs in Dermatology. Cutaneous fungal infections account for between 3.5 and 6.5 million dermatologist office visits per year. Despite their frequency, the diverse presentations of fungal infections often lead to misdiagnosis, resulting in additional costs, time, and delays in proper care.
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Heat-Activated Wound Dressing Has Potential to Heal Chronic Wounds, Pressure Sores
Active adhesive dressing technology was created by Harvard biomedical engineers.
Biomedical engineers said they have created a new wound dressing that contracts in response to body heat, is stretchy, adhesive, antimicrobial and helps to speed healing. The material, called active adhesive dressing, closes wounds “significantly faster” than other commonly used materials and prevents bacterial growth without the need for additional apparatus, the engineers reported.

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