Monthly News & Opportunities

 

March 6, 2026 | V3 #3

 

CLOTT 3 Study Aimed to Improve Blood Clot Prevention for Trauma Patients

The CLOTT 3 project, “Implementing Best-Practice, Patient-Centered Venous Thrombo-embolism (VTE) Prevention in Trauma Centers,” built on earlier research showing that targeted education for both nurses and patients can significantly reduce missed doses of VTE prophylaxis medications.


In previous work, a nurse-focused education program paired with a patient education bundle—including discussions, printed materials, and videos—cut missed doses by nearly half.


Led by Elliott R. Haut, MD, PhD, FACS the study brought those proven strategies into real-world practice in 10 trauma centers nationwide. Participating sites, all members of the Coalition of Leaders in Thromboembolism (CLOTT), implemented the education tools and evaluated how they affected missed medication doses and blood clot prevention in injured patients.


By focusing on patient engagement and clinical workflow, the study represented a key step in translating evidence into practice—helping trauma teams reduce preventable complications and improve outcomes for injured patients.

 

EAST Seeks Multicenter Trial Ideas


The EAST Research Division is seeking high-quality multi- center trial ideas for the 2026 cohort. The committee recommends that proposals focus on the following topics areas:

  • NTRAP questions - (NTRAP information)
  • Emergency General Surgery
  • Geriatric Trauma
  • Injury Prevention


The EAST Multicenter Trials Committee will review and select proposals. Those selected will be listed for recruitment on the EAST Multicenter Study website following IRB approval.

Design for Implementation Conference Defines Urgency of the Moment

The third year of the conference series, "Design for Implementation: The Future of Trauma Clinical Guidance," brought partners together for a final time to focus on how the clinical guidance system they envision could become a reality.


"Every day, everywhere, patients experience preventable suffering attributable to their providers having inadequate access to or application of evidence-informed medicine," said conference PI Lacey LaGrone, MD, MPA, MA, FACS, in her welcome message. "This is our core 'why.'"


In the third year, attendees got a crash course on the swiftly changing landscape: learning together about where Artificial Intelligence (AI) is now, how communities of practice are supporting healthcare delivery across the world, and the economics and power dynamics in our current system of evidence dissemination. 


While the conference series has ended, the work continues. In a final panel discussion with members of CNTR's Evidence to Practice Committee, attendees focused on the imperative that medical professionals maintain control over the systems that deliver guidance and outlined a number of next steps.



CNTR Investigator Resources

Learn How to Employ the Platform Trial Design in Your Research

April 20, 2026

CNTR is launching a Research Methodology Webinar Series! In one-hour virtual sessions, you'll get the specialized expertise to help you design and conduct studies with impact. Sessions end with open Q&A and an opportunity to connect. Join us for tools, mentorship, and practical next steps you can apply immediately to your own work. To suggest topics or offer your expertise for a future session, visit HERE.


For our inaugural session, Gerard Slobogean, MD, MPH (UC Irvine) will discuss the state of the science regarding the platform trial approach, which is capable of simultaneously evaluating multiple interventions. Sheila Sprague, PhD, MSc (McMaster University) will follow with information about the Musculoskeletal Adaptive Platform Trial (MAPT), a platform trial protocol that investigators can license to conduct their own interventional trials.


Learn about this innovative trial design and find out how you can license the MAPT master protocol free of charge or engage the investigator support to provide oversight and trial management. 


When: April 20, 2026 | 3:00 p.m. CST

Fiscal Year 2027 Federal Appropriations Updates


Since the start of the year, CNTR has signed on to several requests to House and Senate Appropriations Committees related to FY27 medical research funding.

  • Ad Hoc Group for Medical Research requests an 8.7% increase to NIH ($51.303B)
  • Academy Health requests full funding of AHRQ at $500M and full staffing
  • ARPA-H Coalition requests at least $1.7B through 2029


Community Project Funding requests are currently being accepted in House offices! These are discreet, one-year projects conducted by nonprofit organizations. They must be a good use of taxpayer funds, have public support, and directly benefit constituents of the district.

 
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