October 29, 2026

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BioPharmGuy

Spent some time in the Rocky Mountains this past week. The local oyster seems to be an endangered species. Bummer. My kid was excited to try them.


Finally

Local theater didn't screen the new Nathan Fielder documentary about Elizabeth Holmes when it was released. They got it last week, but I was traveling.


Good news though. If you are reading this shortly after receiving it, I am currently watching it at my local theater. Based on what I know about Fielder and Holmes, I will have some thoughts to share next week.


-BPG


Weekly BioPharmGuy Directory Edits

This week we added 15 companies and removed zero.


Best New Name:

Carnyx Therapeutics


Worst New Name:

Seragy


Subscribe to our Weekly Update to have the full list of newly added companies sent directly to you each Thursday.

Industry

Heavily Orchestrated Takeover

OpenAI acquired Orchestra Bio and when we saw the news, we thought, wow, they’re really acquiring a drug company and going to use scientists with industry experience to advance their goals of drug discovery. Get ready!


Then we realized Orchestra Bio and Orchestra Biomed are not the same company.


“Orchestra Bio is a platform where people and AI agents work together to advance drug programs”


Ah, so an AI company acquired an AI company. #notnews


Irrelevant

Regenerative dermatology companies are rightly interested in sharing why their advisory board members bring expertise germane to the business. Education, job experience? Yes. Sports played? No.


Robles BioCeutics leads off their PR piece on Mark Skeels by mentioning he is a former professional baseball player.


Having followed baseball for many years and not recognizing his name, we checked the best freely available baseball information resource: baseball reference.


Looks like he made it to high A ball, which is three levels below MLB.


Better than most, but not worth bragging about 32 years later. Maybe stick with the 'Skeels' that are relevant to the job.


#glorydays


Dated Name

We were given a tip that Hinge Bio had relocated at some point this year. When trying to figure out when this happened, we realized Hinge Bio is one of the least Googleable biotech names.


All the results talk about creating a profile for a certain dating app.


Whoever came up with that company name is a Bumbleing fool!


Kentucky Fried Dodo

Good news - Colossal has accelerated their dodo de-extinction timeline, meaning we will be eating dodos sooner than we thought.


Best case will still be about 10 years, but sooner is sooner.


And by the way, what Colossal did has nothing to do with birthing an animal, they just had AI analyze a bunch of genetic stuff. And that has been happening for a long time.


Doing the easy part more efficiently isn't a game changer, y'all. Artificial wombs are the real sticking point in all this de-extinction stuff.


Anyways, back to envisioning our Dod Au Vin recipe.


Funding Finale

Well, this is something you don’t see enough of - a company said they have enough funding and it's time to make money by selling something.


Wow what a concept.


Now technically, they didn't say that. They said this will fund them indefinitely.


But same thing, right?


Any Other Place

This one has been lurking since 2014 and we never heard of it, but man, what a freakin' name: Immagina Biotech.


Perhaps not pronounced how it looks but will always be pronounced that way to us.


ProAbTech

Always a sucker for a weird company name origin, we learned of ProAbTech and were filled with inspiration and joy.


Pro means professional, which is expected.


Then things derailed. In a biotech context, Ab pretty much always means 'Antibody' .


Not for this company. No, Ab stands for 'Above standard of quality'.


Weird.


And Tech doesn't stand for technology, it's 'technological innovation'. Which is just another way of saying technology, but whatever.


Bringing it all together, ProAbTech stands for:


"Professional above standard of quality technological innovation"


If that's really where the name comes from, better off not telling anyone because that is ridiculous.

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Health & Science

USA!

Things are sure great in America, at least assuming you are MEASLES.


Measles is having a hell of a year thanks to idiots.


We now have double the cases of last year with over two months to go. 


USA! USA!


USSR!

Well Russia did it. They transplanted a spinal cord from a Putin supporter into a patient with spinal cord damage.


Sounds impressive, right? Well, no one knows if it worked.


And if it didn't, then it's not one bit impressive because anyone can try to transplant a body part. That's easy enough. It's success that matters.


Will it work?


Spoiler: No. No, it won't.


Sabatini Unsabotaged

A jury awarded former MIT professor David Sabatini $6M in damages from a former graduate student/lover who accused him of forcing her into a nonconsensual relationship.


After the accusations, Sabatini was stripped of tenure at MIT and summarily dismissed.


Was he wrong for being in an intimate relationship with a grad student over which he exerted authority? According to MIT’s policies, yes.


So, while the dismissal may have been proper, the jury clearly felt the defamation of character afterwards which nearly cost him his career went too far. 


How a college professor will pay a $6M verdict is another question.


Doubt It

In what sounds an awful lot like a “chocolate is healthy” news piece, a headline said prenatal depression may benefit baby brain development. 


Sure would be nice, but the bullshit detector is screaming over here.


Cold Cuts

Freezing organs for later use sounds like science fiction, but it is getting closer to science fact.


A University of Minnesota team cryogenically froze pig kidneys and upon thawing, found they were functioning for a couple hours.


The kidneys were perfused with silica-coated iron oxide nanoparticles prior to cooling, enabling them to be rewarmed evenly using an alternating electromagnetic field.


Very cool technology that seems to have real potential. Nice!


Big Stuff

Epulopiscium is one of the largest bacteria in the world. In fact, it can be up to 300 times the size of common ones, which is downright giant.


Scientists announced the discovery of these monsters in human guts, where no one expected to find them.


Upon further investigation, they realized what they had actually found were partially chewed Doritos.

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