The RNA Transcript, March 22, 2021
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This week, March 25–26, 11:00–2:30 pm ET
our 5th Annual RNA Symposium
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Can you match our keynote speakers with their topics? Answer below
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Dear members of the RNA research community,
We are deeply shocked and saddened by the recent attack in Atlanta that resulted in the death of eight people, six of whom are of Asian descent and seven are women. The investigation is examining evidence that this horrific shooting spree might be motivated by misogyny or racism.
We want to extend our deep sympathy and support to all those who are affected by this outrageous act of violence.
The fact is that crimes and aggression against Asian Americans and Pacific Islanders (AAPI) have risen steeply in the last year. Any and all racist and xenophobic behavior has no place in our world.
The University of Michigan Center for RNA Biomedicine, with the University community, condemns such behavior, and stands in solidarity with the AAPI community. We welcome all and believe that diversity makes us better people. Together, we do better science.
With warm regards,
Nils G. Walter and Mats Ljungman
Co-directors of the University of Michigan Center for RNA Biomedicine
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Neurology, Medical School - Faculty: Peter Todd, M.D., Ph.D.
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I’m fascinated with how nucleic acid structure dictates various molecular pathways and mechanisms. Currently I’m investigating how GC-rich RNA repeat expansions promote an aberrant form of translation (RAN translation) and how this process contributes to neurodegenerative disease. I am also investigating how cellular stress regulates RAN translation in a number of neurodegenerative disease models.
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FEATURING OUR KEYNOTE SPEAKERS
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Friday, March 26, 11:05–12:00 pm
Distinguished Professor of Biochemistry University of Utah
“Distinguishing self and non-self dsRNA in vertebrates and invertebrates”
TALK ABSTRACT: When a virus infects an animal cell, including a human cell, double-stranded RNA (dsRNA) matching the viral sequence is found in the cell. Viral dsRNA is recognized as foreign and an immune response is mounted. Recently it has been realized that animal cells encode and synthesize their own dsRNA ....
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Of our five keynote speakers, which scientist is most likely to talk about RNA Splicing?
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Choose below - See the answer next week!
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LAST WEEK QUESTION: Of our five keynote speakers, which scientist is most likely to talk about "RNA destruction?"
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Sponsored by the University of Michigan Biosciences Initiative, and Lexogen.
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Tuesday, March 23, 1:00–2:00 pm ET | U-M, 10x Genomics and University of Michigan Advanced Genomics Core
Featured speaker:
Adriana Suarez, Ph.D., Science & Technology Advisor, 10x Genomics
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Wednesday, March 24, 9:00 am–1:50 pm ET | U-M, College of LSA, College of Engineering & Rackham Graduate School
"Picture a Scientist" by Ian Cheney and Sharon Shattuck. This film spotlights women scientists in academia and chronicles the harassment and discrimination they have faced, as well as their ideas and recommendations to make the STEM fields more diverse, equitable, and inclusive for everyone.
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Wednesday, March 24, 3:00 pm ET | Harvard Medical School Initiative for RNA Medicine Technology Showcase
“glycoRNAs: bridging the gap between glycobiology and RNA biology”
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Li Li, Ph.D., “Efficient chemical RNA copying with 2-aminoimidazole activated nucleotides”
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Monday, April 5, 4:00 pm ET | U-M Center for RNA Biomedicine RNA Innovation Seminar Series
“Direct binding of ESRP1 to regulated transcripts is required for position-dependent splicing regulation”
Postdoctoral Researcher – Carstens Lab/Lynch Lab
Department of Medicine/Department of Biochemistry and Molecular Biophysics, University of Pennsylvania
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Matching our symposium keynote speakers with their topics
Answer from above
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Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below are recent highlights.
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Keywords: ATP hydrolysis; group I intron ribozyme; RNA chaperone; RNA folding
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What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics. Juhlin, C.C., Bertherat, J., Giordano, T.J. et al. Endocr Pathol (2021). https://doi.org/10.1007/s12022-021-09667-0
Abstract: We herein review the histological, genetic, and epigenetic landscapes of benign and malignant adrenal cortical neoplasia from a modern surgical endocrine pathology perspective and highlight key mechanisms of value for diagnostic and prognostic purposes.
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Junior Group Leader Position at the "Genome Integrity, RNA and Cancer" Unit, Institut Curie, France
The "Genome Integrity, RNA and Cancer" Unit is broadly interested in genome integrity and gene expression. This Unit is in a unique position to describe molecular/cellular mechanisms that underlie genome biology at unprecedented levels thanks to in-house complementary expertise in DNA replication, recombination and repair, RNA biology, cytoskeleton, control of cell division and cancer biology. Web site of the Unit. Deadline: April 25th, 2021
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and comments,
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