Newsletter | July 2025

In 2025, the PhRMA Foundation (PhF) is celebrating our 60th anniversary. Since our founding in 1965, we have awarded more than $100 million in grants to over 2,700 researchers at hundreds of U.S. universities and institutions.

Celebrating 60 Years of Launching Careers

Read Our Anniversary Report

On May 31, 1965, the PhRMA Foundation was established to support promising researchers and their novel ideas to foster biopharmaceutical innovation.





Meet the Researchers

Hear directly from our 2025 award recipients about their research and career paths.

Dr. Elizabeth Brunk: Leveraging AI and Single Cell Sequencing to Prevent Harmful DNA Adaptations in Cancer

Ameya Chaudhari: Designing Innovative Meshes for Accelerated Diabetic Wound Healing

Dr. Erick Rodriguez-Palma: Targeting Ion Channels for Fibromyalgia Treatment

Shruti Dharmaraj: Developing Molecules to Treat Allergic Reactions

Dr. Zhimin Huang: Engineering

a Noninvasive, Targeted Approach

to Treating Brain Diseases

Two Pharma Leaders Join Foundation Board

Patrizia Cavazzoni, MD

Chief Medical Officer and Executive Vice President, Pfizer


Dr. Cavazzoni oversees regulatory, pharmacovigilance, safety, epidemiology, and medical research functions at Pfizer. Previously, she served as the director of the U.S. Food and Drug Administration’s Center for Drug Evaluation and Research, where she led regulatory and policy decisions on prescription and over-the-counter medicines. Her extensive pharmaceutical industry experience includes senior executive roles at Pfizer, Eli Lilly, and Sanofi.

Fiona H. Marshall, PhD

President of Biomedical Research, Novartis


Dr. Marshall leads a global team across nine Novartis research sites, where she drives the discovery of high-impact medicines. Previously, she was Senior Vice President and Global Head of Discovery Sciences, Preclinical Development, and Translational Medicine at Merck. Prior to that, she co-founded Heptares Therapeutics, a UK-based biotech focused on structure-based drug design, and held senior scientific roles at Millennium Pharmaceuticals and GSK.

From the Blog

Eliciting Patient Preferences to Assess the Value of Breast and Prostate Cancer Therapies

The U.S. spends billions of dollars each year on medicines to treat 320,000 new cases of breast cancer and 314,00 new cases of prostate cancer. But health care stakeholders — patients, providers, and payers — often have differing opinions when it comes to the “value” of new medicines.


William Padula, PhD, of the University of Southern California received a $500,000 Frontier Award in Value Assessment from the PhRMA Foundation to conduct research on the value of therapies for metastatic breast and prostate cancers, with a focus on the inclusion of patient perspectives. Read our latest blog to learn how Padula is engaging patients in his research.

Awardee Publications

Congrats to these Foundation-funded researchers on their recent work.

**Indicates research directly supported by a PhRMA Foundation award.

**RNApysoforms: fast rendering interactive visualization of RNA isoform structure and expression in Python, Bioinformatics Advances

Bernardo Aguzzoli Heberle (PhF25) and Mark T. W. Ebbert (PhF17), University of Kentucky

**A novel structural modeling magnitude and orientation radiomic descriptor for evaluating response to neoadjuvant therapy in rectal cancers via MRI, NPJ Precision Oncology

Charlems Alvarez-Jimenez, PhD (PhF24), Case Western Reserve University

**Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions, Nature

Brian M. Andersen, MD, PhD (PhF22), Brigham and Women’s Hospital, Harvard Medical School


**Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity, Nature

Brian M. Andersen, MD, PhD (PhF22), Brigham and Women’s Hospital, Harvard Medical School


**CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model, Nature Neuroscience

Brian M. Andersen, MD, PhD (PhF22), Brigham and Women’s Hospital, Harvard Medical School

**Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas, Advanced Materials

Chandrabali Bhattacharya, PhD (PhF24), University of Nevada, Las Vegas

**EHBP1 Suppresses Liver Fibrosis in Metabolic Dysfunction-associated Steatohepatitis, Cell Metabolism

Bishuang Cai, PhD (PhF21), Icahn School of Medicine at Mount Sinai


**Resolvin D1–mediated cellular crosstalk protects against metabolic dysfunction-associated steatohepatitis, JHEP Reports

Bishuang Cai, PhD (PhF21), Icahn School of Medicine at Mount Sinai

**Harnessing and delivering microbial metabolites as therapeutics via advanced pharmaceutical approaches, Pharmacology & Therapeutics

Shijie Cao, PhD (PhF24), University of Washington

**Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection, Nature Communications

Anh T.Q. Cong, MS (PhF25), Mayo Clinic

**Glioma-neuronal circuit remodeling induces regional immunosuppression, Nature Communications

Andy G. S. Daniel, PhD (PhF22), University of California, San Francisco


Gabapentinoids confer survival benefit in human glioblastoma, Nature Communications

Andy G. S. Daniel, PhD (PhF22), University of California, San Francisco


Predicting therapeutic clinical trial enrollment for adult patients with low- and high-grade glioma using supervised machine learning, Science Advances

Andy G. S. Daniel, PhD (PhF22), University of California, San Francisco

Racial Disparities in Longitudinal Frailty State Transitions Among Older Cancer Survivors, Journal of Geriatric Oncology

Emilie Duchesneau, PhD, MSPH, (PhF24) Wake Forest University

**Discovery of 2,4,5-Substituted Benzoxazole Derivatives as Pks13 Inhibitors via the Scaffold Hopping Strategy, ACS Infectious Diseases

Priscila Halicki, PhD (PhF 23), University of Central Florida


**Synthesis and evaluation of Trehalose-Pks13 inhibitor conjugates targeting mycobacteria, Carbohydrate Research

Priscila Halicki, PhD (PhF 23), University of Central Florida

**Risk factors, behaviors, and adverse health outcomes of financial toxicity in adult chronic myeloid leukemia survivors: a theory‑based structural equation model, Supportive Care in Cancer

Ruiqi Jin, RN, MSN, PhD (PhF23), Emory University

Web-Based Cancer Symptom Self-Management System: A Randomized Clinical Trial, JAMA Network Open

Maja Kuharic, MPharm, MSc, PhD (PhF25), Northwestern University


Frequency and severity response scales for pain and discomfort: psychometric insights from EQ-HWB, Quality of Life Research

Maja Kuharic, MPharm, MSc, PhD (PhF25), Northwestern University


Psychometric evaluation of the NoMAD instrument in cancer care settings: assessing factorial validity, measurement invariance, and differential item functioning, Implementation Science Communications

Maja Kuharic, MPharm, MSc, PhD (PhF25), Northwestern University

Roles of AI-Based Synthetic Data in Health Economics and Outcomes Research, Value in Health

Tim C. Lai, BPharm (PhF25) and Surachat Ngorsuraches, PhD (PhF23), Auburn University

**How I individualize treatment for chronic-phase CML, Blood

Ariel Leyte-Vidal (PhF25), University of Miami

Implementing the Generalized Risk-Adjusted Cost-Effectiveness Model for Sickle Cell Disease: A Case Study, Value in Health

Karen Mulligan, PhD (PhF23), University of Southern California

Innate psychological needs of autonomy, competence, and provider communication as determinants of patients' satisfaction and self-rated health, International Journal for Quality in Health Care

Helen Omuya, MPA (PhF23), University of Wisconsin-Madison

Opioid Use Disorder in Older Adults: a Narrative Review, Current Geriatrics Reports

Jarratt Pytell, MD (PhF23), University of Colorado

**Heterogeneous treatment effects of GLP-1RAs and SGLT2is on risk of Alzheimer's disease and related dementia in patients with type 2 diabetes: Insights from a real-world target trial emulation, Alzheimer's & Dementia

Huilin Tang, MS (PhF23), University of Florida


**Glycated hemoglobin and body mass index as mediators of GLP-1RAs and Alzheimer's disease and related dementias in patients with type 2 diabetes, Alzheimer's & Dementia

Huilin Tang, MS (PhF23), University of Florida

**A percolation phase transition controls complement protein coating of surfaces, Cell

Zhicheng Wang, PhD (PhF23), University of Pennsylvania

**Real-world Smartphone Data Predicts Mood After Ischemic Stroke and TIA Symptoms and may Constitute Digital Endpoints: A Proof-of-Concept Study, Mayo Clinic Proceedings: Digital Health

Stephanie Zawada, MS, PhD (PhF23), Mayo Clinic

Awardee News

Eleanor Agosta (PhF25) of Rutgers University received the Massimo Tommasino Award for best presentation from a young researcher at the 7th Meeting on Emerging Issues in Oncogenic Virus Research in June.

Shamimur Akanda, PhD (PhF25) of Washington University in St. Louis received a poster award in Washington University Musculoskeletal Research Symposium for his PhF-supported research.

Brian Andersen, MD, PhD (PhF22) of Brigham and Women’s Hospital received a Career Development Award to establish his own lab as a neuro-oncologist at Boston Veterans Affairs.

Christopher Cadham, MPH, PhD (PhF23) of the University of Michigan successfully defended his dissertation and in the fall will start as an assistant professor at the Fred Hutchinson Cancer Center in Seattle. He also presented his PhF-funded research at the annual meeting of the Society for Medical Decision Making in June.

Shruti Dharmaraj, MS (PhF25) of the University of Maryland, Baltimore, was selected for an oral presentation at the American Association for Immunologists conference in May and her abstract won a trainee award. She was also selected for an oral presentation at the Controlled Release Society Conference in July.

Liang Hao, PhD (PhF23) of Boston University received the 2025 Beckman Young Investigator Award and the Rainin Foundation Innovator Award.

Wesam Ismail, PhD (PhF24) of the University of Iowa successfully defended his dissertation and passed his final exam.

Maja Kuharic, MPharm, MSc, PhD (PhF25) of Northwestern University chaired the 5th EuroQol Early Career Meeting held in March for the second year in a row.

Piaopiao Li (PhF24) of the University of Florida received the Diabetes In Primary Care Interest Group Early Career Abstract Award at the 2025 American Diabetes Association Scientific Sessions in June. She was also interviewed by HCPLive about her work: VA MOVE! Reinforces Why Veteran-Specific Diabetes Prevention Research Matters.

William Padula, PhD (PhF23) was promoted to associate professor with tenure at the University of Southern California. "My grants from PhRMA Foundation over the past several years have played an enormous role in the scholarship carried out to receive that promotion," he said.

Xiaoshu Pan, PhD (PhF23) of the University of Florida gave an oral talk about her PhF-supported research at the American Society of Gene + Cell Therapy annual meeting in May and received the organization's Meritorious Abstract Travel Award.

Wei "Adelyn" Tsai (PhF25) or Mayo Clinic gave a talk featuring preliminary data for my PhF fellowship project at the AD/PD 2025 International Conference in April.

Marek D. Zorawski, PhD (PhF24) of Duke University successfully defended his PhD and presented a poster at the American Association for Cancer Research meeting in April.

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